|
1
|
Baker Bros. Advisors
New York
|
$27.6M
|
–
|
–
|
–
|
|
|
2
|
Redmile Group
San Francisco,
California
|
$25.4M
|
-$3.15M
|
-20,600
|
-11%
|
|
|
3
|
|
$19.3M
|
+$234K
|
+1,526
|
+1%
|
|
|
4
|
Pictet Asset Management (Switzerland)
Geneva 73,
Switzerland
|
$19.3M
|
+$20.4M
|
+133,225
|
New
|
|
|
5
|
Vanguard Group
Malvern,
Pennsylvania
|
$11.6M
|
+$130K
|
+850
|
+1%
|
|
|
6
|
Boxer Capital
San Diego,
California
|
$10.9M
|
–
|
–
|
–
|
|
|
7
|
Opaleye Management
Boston,
Massachusetts
|
$7.57M
|
-$834K
|
-5,445
|
-9%
|
|
|
8
|
Point72 Asset Management
Stamford,
Connecticut
|
$7.23M
|
+$895K
|
+5,845
|
+13%
|
|
|
9
|
EcoR1 Capital
San Francisco,
California
|
$6.22M
|
-$11.5M
|
-74,909
|
-64%
|
|
|
10
|
Candriam SCA
Strassen, Luxembourg,
Luxembourg
|
$6.2M
|
+$2.65M
|
+17,308
|
+68%
|
|
|
11
|
Renaissance Technologies
New York
|
$5.47M
|
+$1.38M
|
+9,045
|
+31%
|
|
|
12
|
Geode Capital Management
Boston,
Massachusetts
|
$4.47M
|
+$269K
|
+1,760
|
+6%
|
|
|
13
|
State Street
Boston,
Massachusetts
|
$4.41M
|
-$4.78M
|
-31,234
|
-51%
|
|
|
14
|
|
$4.32M
|
-$256K
|
-1,675
|
-5%
|
|
|
15
|
Alkeon Capital Management
New York
|
$3.62M
|
–
|
–
|
–
|
|
|
16
|
Northern Trust
Chicago,
Illinois
|
$2.54M
|
-$100K
|
-656
|
-4%
|
|
|
17
|
Millennium Management
New York
|
$2.03M
|
+$938K
|
+6,127
|
+78%
|
|
|
18
|
ACT Capital Management
Wayne,
Pennsylvania
|
$1.73M
|
–
|
–
|
–
|
|
|
19
|
Bank of America
Charlotte,
North Carolina
|
$1.36M
|
+$28.6K
|
+187
|
+2%
|
|
|
20
|
Two Sigma Advisers
New York
|
$1.26M
|
+$880K
|
+5,745
|
+192%
|
|
|
21
|
Nuveen
Charlotte,
North Carolina
|
$1.16M
|
-$4.9K
|
-32
|
-0.5%
|
|
|
22
|
Royce & Associates
New York
|
$1.05M
|
–
|
–
|
–
|
|
|
23
|
Granahan Investment Management
Waltham,
Massachusetts
|
$906K
|
-$534K
|
-3,487
|
-36%
|
|
|
24
|
Bank of New York Mellon
New York
|
$887K
|
+$58.3K
|
+381
|
+7%
|
|
|
25
|
Two Sigma Investments
New York
|
$869K
|
+$621K
|
+4,056
|
+207%
|
|
