|
1
|
Fidelity Investments
Boston,
Massachusetts
|
$178M
|
+$187K
|
+12,515
|
+0.1%
|
|
|
2
|
T. Rowe Price Associates
Baltimore,
Maryland
|
$156M
|
-$4.06M
|
-271,600
|
-3%
|
|
|
3
|
|
$90.8M
|
+$16.7M
|
+1,117,900
|
+24%
|
|
|
4
|
Perceptive Advisors
New York
|
$71.5M
|
-$517K
|
-34,600
|
-0.8%
|
|
|
5
|
BB Biotech
Schaffhausen,
Switzerland
|
$48.8M
|
+$448K
|
+30,000
|
+1%
|
|
|
6
|
BlackRock Fund Advisors
San Francisco,
California
|
$40.1M
|
-$298K
|
-19,944
|
-0.8%
|
|
|
7
|
Vanguard Group
Malvern,
Pennsylvania
|
$35.8M
|
+$1.03M
|
+68,679
|
+3%
|
|
|
8
|
State Street
Boston,
Massachusetts
|
$34.7M
|
+$646K
|
+43,254
|
+2%
|
|
|
9
|
BlackRock Institutional Trust
San Francisco,
California
|
$32.5M
|
-$56K
|
-3,748
|
-0.2%
|
|
|
10
|
Franklin Resources
San Mateo,
California
|
$28.8M
|
-$5.47M
|
-365,800
|
-17%
|
|
|
11
|
Visium Asset Management
New York
|
$28M
|
+$42.4K
|
+2,840
|
+0.2%
|
|
|
12
|
ArrowMark Colorado Holdings
Denver,
Colorado
|
$24.2M
|
-$1.68M
|
-112,094
|
-7%
|
|
|
13
|
Tekla Capital Management
Boston,
Massachusetts
|
$20.1M
|
+$7.35M
|
+491,460
|
+62%
|
|
|
14
|
Great Point Partners
Greenwich,
Connecticut
|
$18.2M
|
-$5.24M
|
-350,364
|
-23%
|
|
|
15
|
Capital World Investors
Los Angeles,
California
|
$18M
|
–
|
–
|
–
|
|
|
16
|
Loomis, Sayles & Company
Boston,
Massachusetts
|
$16.2M
|
-$357K
|
-23,874
|
-2%
|
|
|
17
|
Janus Henderson Investors US
Denver,
Colorado
|
$15.7M
|
+$4.15M
|
+277,667
|
+38%
|
|
|
18
|
Deutsche Bank
Frankfurt Am Main Ge,
Germany
|
$14.9M
|
+$1.66M
|
+111,004
|
+13%
|
|
|
19
|
BlackRock Advisors
Wilmington,
Delaware
|
$14.8M
|
-$1.38M
|
-92,418
|
-9%
|
|
|
20
|
Citadel Advisors
Miami,
Florida
|
$14.7M
|
+$9.97M
|
+667,174
|
+249%
|
|
|
21
|
Northern Trust
Chicago,
Illinois
|
$14.6M
|
+$248K
|
+16,626
|
+2%
|
|
|
22
|
|
$14.6M
|
+$590K
|
+39,500
|
+4%
|
|
|
23
|
Wellington Management Group
Boston,
Massachusetts
|
$13.6M
|
+$216K
|
+14,440
|
+2%
|
|
|
24
|
Cormorant Asset Management
Boston,
Massachusetts
|
$13.3M
|
+$8.22M
|
+550,000
|
+183%
|
|
|
25
|
Thrivent Financial for Lutherans
Minneapolis,
Minnesota
|
$10.3M
|
-$232K
|
-15,500
|
-2%
|
|
