|
1
|
Fidelity Investments
Boston,
Massachusetts
|
$169M
|
+$1.08M
|
+76,809
|
+0.7%
|
|
|
2
|
T. Rowe Price Associates
Baltimore,
Maryland
|
$152M
|
-$24K
|
-1,700
|
-0%
|
|
|
3
|
|
$69.4M
|
-$10.9M
|
-775,300
|
-14%
|
|
|
4
|
Perceptive Advisors
New York
|
$68.3M
|
-$275K
|
-19,500
|
-0.4%
|
|
|
5
|
BB Biotech
Schaffhausen,
Switzerland
|
$45.8M
|
+$1.27M
|
+90,000
|
+3%
|
|
|
6
|
BlackRock Fund Advisors
San Francisco,
California
|
$38.2M
|
-$3.26M
|
-231,213
|
-8%
|
|
|
7
|
Vanguard Group
Malvern,
Pennsylvania
|
$32.9M
|
-$84.5K
|
-5,985
|
-0.3%
|
|
|
8
|
Franklin Resources
San Mateo,
California
|
$32.7M
|
–
|
–
|
–
|
|
|
9
|
State Street
Boston,
Massachusetts
|
$32.2M
|
-$1.01M
|
-71,769
|
-3%
|
|
|
10
|
BlackRock Institutional Trust
San Francisco,
California
|
$30.8M
|
-$61.5K
|
-4,359
|
-0.2%
|
|
|
11
|
Visium Asset Management
New York
|
$26.5M
|
-$3.06M
|
-216,514
|
-11%
|
|
|
12
|
ArrowMark Colorado Holdings
Denver,
Colorado
|
$24.6M
|
+$5.65M
|
+400,252
|
+32%
|
|
|
13
|
Great Point Partners
Greenwich,
Connecticut
|
$22.4M
|
+$12.6M
|
+892,103
|
+144%
|
|
|
14
|
Capital World Investors
Los Angeles,
California
|
$17.1M
|
–
|
–
|
–
|
|
|
15
|
Loomis, Sayles & Company
Boston,
Massachusetts
|
$15.7M
|
+$2.67M
|
+188,869
|
+22%
|
|
|
16
|
BlackRock Advisors
Wilmington,
Delaware
|
$15.4M
|
-$369K
|
-26,171
|
-2%
|
|
|
17
|
Northern Trust
Chicago,
Illinois
|
$13.6M
|
-$1.16M
|
-81,883
|
-8%
|
|
|
18
|
|
$13.2M
|
–
|
–
|
–
|
|
|
19
|
Wellington Management Group
Boston,
Massachusetts
|
$12.6M
|
+$4.02M
|
+284,520
|
+50%
|
|
|
20
|
Deutsche Bank
Frankfurt Am Main Ge,
Germany
|
$12.5M
|
+$1.49M
|
+105,483
|
+14%
|
|
|
21
|
Tekla Capital Management
Boston,
Massachusetts
|
$11.7M
|
+$5.12M
|
+362,700
|
+85%
|
|
|
22
|
Janus Henderson Investors US
Denver,
Colorado
|
$10.7M
|
+$675K
|
+47,824
|
+7%
|
|
|
23
|
Thrivent Financial for Lutherans
Minneapolis,
Minnesota
|
$9.96M
|
-$6.03K
|
-427
|
-0.1%
|
|
|
24
|
|
$9.23M
|
-$1.69M
|
-119,491
|
-16%
|
|
|
25
|
Baker Bros. Advisors
New York
|
$8.23M
|
+$1.51M
|
+106,716
|
+24%
|
|
