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Nautilus Biotechnolgy
NAUT

68 hedge funds and large institutions have $48.9M invested in Nautilus Biotechnolgy in 2025 Q3 according to their latest regulatory filings, with 9 funds opening new positions, 8 increasing their positions, 29 reducing their positions, and 12 closing their positions.

New
Increased
Maintained
Reduced
Closed

13% more capital invested

Capital invested by funds: $43.3M → $48.9M (+$5.6M)

0% more funds holding in top 10

Funds holding in top 10: 3 → 3 (0)

1.53% less ownership

Funds ownership: 47.37% → 45.84% (-1.5%)

4% less funds holding

Funds holding: 71 → 68 (-3)

25% less first-time investments, than exits

New positions opened: 9 | Existing positions closed: 12

72% less repeat investments, than reductions

Existing positions increased: 8 | Existing positions reduced: 29

Holders
68
Holders Change
-3
Holders Change %
-4.23%
% of All Funds
0.89%
Holding in Top 10
3
Holding in Top 10 Change
–
Holding in Top 10 Change %
–
% of All Funds
0.04%
New
9
Increased
8
Reduced
29
Closed
12
Calls
–
Puts
–
Net Calls
–
Net Calls Change
–

Top Buyers

Rank Fund Capital Flow
1
Renaissance Technologies
Renaissance Technologies
New York
+$285K
2
Acadian Asset Management
Acadian Asset Management
Massachusetts
+$128K
3
CGL
Clarius Group LLC
Washington
+$110K
4
CA
Crewe Advisors
Utah
+$100K
5
GCP
GSA Capital Partners
United Kingdom
+$60.5K

Top Sellers

Rank Fund Capital Flow
1
AI
ArchPoint Investors
Florida
-$451K
2
BlackRock
BlackRock
New York
-$314K
3
ST
Sentinel Trust
Texas
-$203K
4
YIH
Y-Intercept (HK)
Hong Kong
-$163K
5
Goldman Sachs
Goldman Sachs
New York
-$145K
Name Holding Trade Value Shares
Change 		Change in
Stake
BCM
26
Bridgeway Capital Management
Texas
$106K – – –
Northern Trust
27
Northern Trust
Illinois
$99.6K -$22.5K -30,631 -21%
Goldman Sachs
28
Goldman Sachs
New York
$99.5K -$145K -197,222 -63%
Qube Research & Technologies (QRT)
29
Qube Research & Technologies (QRT)
United Kingdom
$43.7K -$7.7K -10,471 -17%
Barclays
30
Barclays
United Kingdom
$40.8K -$7.23K -9,835 -17%
HSBC Holdings
31
HSBC Holdings
United Kingdom
$40.1K – – –
XT
32
XTX Topco
Cayman Islands
$38.6K -$15K -20,470 -31%
Fayez Sarofim & Co
33
Fayez Sarofim & Co
Texas
$38K – – –
ATPW
34
Ashton Thomas Private Wealth
Arizona
$38K +$33.1K +45,000 New
PWM
35
Palumbo Wealth Management
New York
$35.6K +$335 +456 +1%
PCM
36
Presidio Capital Management
California
$29.3K – – –
BPWM
37
Badgley Phelps Wealth Managers
Washington
$25.3K – – –
Morgan Stanley
38
Morgan Stanley
New York
$21.7K -$21.2K -28,849 -53%
VF
39
Virtu Financial
New York
$17K +$14.5K +19,683 New
PAS
40
Point72 Asia (Singapore)
Singapore
$13.7K -$12K -16,306 -50%
CFO
41
Callan Family Office
Pennsylvania
$12.5K -$25K -34,064 -70%
CG
42
Caprock Group
Idaho
$11.6K +$12.6K +17,090 New
VCWA
43
Vanguard Capital Wealth Advisors
Colorado
$11.4K -$1.84K -2,500 -16%
FIA
44
FNY Investment Advisers
New York
$11K – – –
Fidelity Investments
45
Fidelity Investments
Massachusetts
$7.32K -$11.6K -15,838 -65%
TRCT
46
Tower Research Capital (TRC)
New York
$4.73K -$11.7K -15,978 -74%
Rockefeller Capital Management
47
Rockefeller Capital Management
New York
$4.22K +$3.67K +5,000 New
JP Morgan Chase
48
JP Morgan Chase
New York
$1.79K -$151 -206 -9%
BNP Paribas Financial Markets
49
BNP Paribas Financial Markets
France
$1.24K -$1.44K -1,963 -57%
Royal Bank of Canada
50
Royal Bank of Canada
Ontario, Canada
$1K -$354 -482 -21%
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NAUT Hedge Fund Activity: Q3 2025 in Review

68 of the 7,621 institutional investors tracked by Wall St. Rank reported a position in Nautilus Biotechnolgy (NAUT) for Q3 2025, worth a combined $48.9M — up 13% from $43.3M a quarter earlier.

Sellers outnumbered buyers: 12 funds closed out of NAUT and 9 opened new positions — a net loss of 3 holders — while 29 trimmed existing stakes and 8 added.

The largest buyer was Renaissance Technologies, adding an estimated $285K. The largest seller was ArchPoint Investors, exiting entirely with an estimated $451K sold.

  • 68 institutional investors held Nautilus Biotechnolgy (NAUT) as of Q3 2025, down from 71 in Q2 2025.
  • Funds reported $48.9M of Nautilus Biotechnolgy stock for Q3 2025, up 13% quarter-over-quarter.
  • 9 funds opened new Nautilus Biotechnolgy positions in Q3 2025 and 12 closed out, a net change of -3 holders.
  • The largest Nautilus Biotechnolgy buyer in Q3 2025 was Renaissance Technologies, an estimated $285K added.
  • The largest Nautilus Biotechnolgy seller in Q3 2025 was ArchPoint Investors, an estimated $451K sold.

Based on aggregated 13F filings for Q3 2025.