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Nautilus Biotechnolgy

71 hedge funds and large institutions have $43.3M invested in Nautilus Biotechnolgy in 2025 Q2 according to their latest regulatory filings, with 12 funds opening new positions, 25 increasing their positions, 17 reducing their positions, and 28 closing their positions.

New
Increased
Maintained
Reduced
Closed

47% more repeat investments, than reductions

Existing positions increased: 25 | Existing positions reduced: 17

0% more funds holding in top 10

Funds holding in top 10: 33 (0)

2.39% less ownership

Funds ownership: 49.76%47.37% (-2.4%)

19% less funds holding

Funds holding: 8871 (-17)

20% less capital invested

Capital invested by funds: $54M → $43.3M (-$10.7M)

57% less first-time investments, than exits

New positions opened: 12 | Existing positions closed: 28

Holders
71
Holders Change
-17
Holders Change %
-19.32%
% of All Funds
0.93%
Holding in Top 10
3
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
0.04%
New
12
Increased
25
Reduced
17
Closed
28
Calls
$115K
Puts
Net Calls
+$115K
Net Calls Change
+$95K
Name Holding Trade Value Shares
Change
Change in
Stake
GCP
26
GSA Capital Partners
United Kingdom
$128K +$124K +164,396 +1,314%
Northern Trust
27
Northern Trust
Illinois
$108K -$257K -342,587 -70%
Susquehanna International Group
28
Susquehanna International Group
Pennsylvania
$107K +$60.3K +80,204 +119%
BCM
29
Bridgeway Capital Management
Texas
$90.6K +$56.3K +75,000 +150%
Squarepoint
30
Squarepoint
New York
$73.8K +$58.5K +77,923 +326%
MA
31
MYDA Advisors
New York
$55.4K +$57.4K +76,413 New
LCM
32
Landscape Capital Management
New Jersey
$51.7K +$53.6K +71,301 New
Acadian Asset Management
33
Acadian Asset Management
Massachusetts
$48K +$5.61K +7,473 +12%
XT
34
XTX Topco
Cayman Islands
$48K +$23K +30,641 +86%
CSS
35
Cubist Systematic Strategies
Connecticut
$45.2K +$46.8K +62,347 New
Qube Research & Technologies (QRT)
36
Qube Research & Technologies (QRT)
United Kingdom
$45K +$46.7K +62,138 New
Barclays
37
Barclays
United Kingdom
$42.1K -$32.2K -42,878 -42%
Morgan Stanley
38
Morgan Stanley
New York
$39.6K -$88.3K -117,584 -68%
HSBC Holdings
39
HSBC Holdings
United Kingdom
$36.3K -$4.17K -5,549 -10%
CFO
40
Callan Family Office
Pennsylvania
$35.4K +$36.7K +48,894 New
JG
41
Jain Global
New York
$32.7K +$33.9K +45,100 New
Fayez Sarofim & Co
42
Fayez Sarofim & Co
Texas
$32.6K
AQR Capital Management
43
AQR Capital Management
Connecticut
$30.5K +$15.5K +20,650 +96%
PWM
44
Palumbo Wealth Management
New York
$30.2K +$375 +499 +1%
PCM
45
Presidio Capital Management
California
$25.1K +$18.5K +24,664 +247%
PAS
46
Point72 Asia (Singapore)
Singapore
$23.6K +$24.5K +32,577 New
BPWM
47
Badgley Phelps Wealth Managers
Washington
$21.7K
Fidelity Investments
48
Fidelity Investments
Massachusetts
$17.8K +$9.45K +12,584 +106%
TRCT
49
Tower Research Capital (TRC)
New York
$15.6K +$8.13K +10,827 +101%
GSC
50
Ground Swell Capital
South Carolina
$14.5K +$15.1K +20,061 New

NAUT Hedge Fund Activity: Q2 2025 in Review

71 of the 7,596 institutional investors tracked by Wall St. Rank reported a position in Nautilus Biotechnolgy (NAUT) for Q2 2025, worth a combined $43.3M — down 20% from $54M a quarter earlier.

Sellers outnumbered buyers: 28 funds closed out of NAUT and 12 opened new positions — a net loss of 16 holders — while 17 trimmed existing stakes and 25 added.

The largest buyer was Millennium Management, adding an estimated $727K. The largest seller was BlackRock, cutting an estimated $1.63M.

  • 71 institutional investors held Nautilus Biotechnolgy (NAUT) as of Q2 2025, down from 88 in Q1 2025.
  • Funds reported $43.3M of Nautilus Biotechnolgy stock for Q2 2025, down 20% quarter-over-quarter.
  • 12 funds opened new Nautilus Biotechnolgy positions in Q2 2025 and 28 closed out, a net change of -16 holders.
  • The largest Nautilus Biotechnolgy buyer in Q2 2025 was Millennium Management, an estimated $727K added.
  • The largest Nautilus Biotechnolgy seller in Q2 2025 was BlackRock, an estimated $1.63M sold.

Based on aggregated 13F filings for Q2 2025.