|
1
|
Fidelity Investments
Boston,
Massachusetts
|
$263M
|
+$146M
|
+2,809,789
|
+109%
|
|
|
2
|
Wellington Management Group
Boston,
Massachusetts
|
$163M
|
+$11.2M
|
+214,857
|
+7%
|
|
|
3
|
T. Rowe Price Associates
Baltimore,
Maryland
|
$97.5M
|
+$32.5M
|
+624,243
|
+45%
|
|
|
4
|
|
$88.1M
|
-$6.01M
|
-115,596
|
-6%
|
|
|
5
|
Vanguard Group
Malvern,
Pennsylvania
|
$81.1M
|
+$33.1M
|
+637,519
|
+62%
|
|
|
6
|
Deerfield Management
New York
|
$52.2M
|
+$3.53M
|
+68,000
|
+7%
|
|
|
7
|
Farallon Capital Management
San Francisco,
California
|
$50.7M
|
+$9.13M
|
+175,546
|
+20%
|
|
|
8
|
PFM Health Sciences
San Francisco,
California
|
$46.4M
|
-$17.9M
|
-343,449
|
-27%
|
|
|
9
|
TRV GP II
Boston,
Massachusetts
|
$43.2M
|
-$104M
|
-2,000,000
|
-69%
|
|
|
10
|
Perceptive Advisors
New York
|
$40.7M
|
+$6.44M
|
+123,953
|
+17%
|
|
|
11
|
Cormorant Asset Management
Boston,
Massachusetts
|
$37.4M
|
-$1.7M
|
-32,637
|
-4%
|
|
|
12
|
Hillhouse Investment Management
Grand Cayman,
Cayman Islands
|
$37M
|
+$15M
|
+289,340
|
+62%
|
|
|
13
|
TRV GP III
Boston,
Massachusetts
|
$33.2M
|
-$42.4M
|
-816,326
|
-55%
|
|
|
14
|
|
$27.3M
|
–
|
–
|
–
|
|
|
15
|
State Street
Boston,
Massachusetts
|
$23.7M
|
+$815K
|
+15,679
|
+3%
|
|
|
16
|
Credit Suisse
Zurich,
Switzerland
|
$20.2M
|
+$8.35M
|
+160,613
|
+63%
|
|
|
17
|
Foresite Capital Management III
Larkspur,
California
|
$19.2M
|
+$4.55M
|
+87,602
|
+29%
|
|
|
18
|
Foresite Capital Management IV
Larkspur,
California
|
$19.1M
|
+$4.29M
|
+82,598
|
+27%
|
|
|
19
|
|
$18.6M
|
-$5.33M
|
-102,548
|
-21%
|
|
|
20
|
Pictet Asset Management (UK)
London,
United Kingdom
|
$16M
|
-$113K
|
-2,168
|
-0.7%
|
|
|
21
|
Baker Bros. Advisors
New York
|
$14.2M
|
-$3.38M
|
-65,000
|
-18%
|
|
|
22
|
Fernwood Investment Management
Quincy,
Massachusetts
|
$13.6M
|
+$791K
|
+15,219
|
+6%
|
|
|
23
|
|
$12.7M
|
+$104K
|
+2,007
|
+0.8%
|
|
|
24
|
TimesSquare Capital Management
New York
|
$12.5M
|
+$13.3M
|
+256,315
|
New
|
|
|
25
|
Wells Fargo
San Francisco,
California
|
$12M
|
-$5.68M
|
-109,295
|
-31%
|
|
