|
1
|
Fidelity Investments
Boston,
Massachusetts
|
–
|
-$1.08B
|
-7,950,467
|
Closed
|
|
|
2
|
T. Rowe Price Associates
Baltimore,
Maryland
|
–
|
-$747M
|
-5,480,943
|
Closed
|
|
|
3
|
Vanguard Group
Malvern,
Pennsylvania
|
–
|
-$602M
|
-4,414,431
|
Closed
|
|
|
4
|
|
–
|
-$578M
|
-4,237,157
|
Closed
|
|
|
5
|
Baker Bros. Advisors
New York
|
–
|
-$410M
|
-3,009,344
|
Closed
|
|
|
6
|
Wellington Management Group
Boston,
Massachusetts
|
–
|
-$317M
|
-2,324,024
|
Closed
|
|
|
7
|
Avoro Capital Advisors
New York
|
–
|
-$257M
|
-1,885,000
|
Closed
|
|
|
8
|
Perceptive Advisors
New York
|
–
|
-$190M
|
-1,395,017
|
Closed
|
|
|
9
|
|
–
|
-$176M
|
-1,290,801
|
Closed
|
|
|
10
|
Farallon Capital Management
San Francisco,
California
|
–
|
-$167M
|
-1,225,000
|
Closed
|
|
|
11
|
Bellevue Group
Kuesnacht,
Switzerland
|
–
|
-$154M
|
-1,128,400
|
Closed
|
|
|
12
|
State Street
Boston,
Massachusetts
|
–
|
-$146M
|
-1,074,189
|
Closed
|
|
|
13
|
|
–
|
-$128M
|
-936,931
|
Closed
|
|
|
14
|
|
–
|
-$119M
|
-870,000
|
Closed
|
|
|
15
|
Geode Capital Management
Boston,
Massachusetts
|
–
|
-$106M
|
-774,288
|
Closed
|
|
|
16
|
|
–
|
-$103M
|
-753,567
|
Closed
|
|
|
17
|
Janus Henderson Group
London,
|
–
|
-$98.7M
|
-723,989
|
Closed
|
|
|
18
|
Deerfield Management
New York
|
–
|
-$96M
|
-704,000
|
Closed
|
|
|
19
|
HHLR Advisors
Grand Cayman,
Cayman Islands
|
–
|
-$94.2M
|
-690,658
|
Closed
|
|
|
20
|
Pictet Asset Management (UK)
London,
United Kingdom
|
–
|
-$88.2M
|
-647,038
|
Closed
|
|
|
21
|
Northern Trust
Chicago,
Illinois
|
–
|
-$87.1M
|
-638,688
|
Closed
|
|
|
22
|
Eventide Asset Management
Boston,
Massachusetts
|
–
|
-$84.7M
|
-621,000
|
Closed
|
|
|
23
|
Driehaus Capital Management
Chicago,
Illinois
|
–
|
-$70.6M
|
-517,691
|
Closed
|
|
|
24
|
Ameriprise
Minneapolis,
Minnesota
|
–
|
-$69.8M
|
-512,165
|
Closed
|
|
|
25
|
Credit Suisse
Zurich,
Switzerland
|
–
|
-$68.6M
|
-502,861
|
Closed
|
|
