|
1
|
Fidelity Investments
Boston,
Massachusetts
|
$343M
|
+$33.9M
|
+648,994
|
+10%
|
|
|
2
|
|
$208M
|
–
|
–
|
–
|
|
|
3
|
Deerfield Management
New York
|
$170M
|
+$34.4M
|
+659,138
|
+24%
|
|
|
4
|
Commodore Capital
New York
|
$167M
|
+$7.83M
|
+150,000
|
+5%
|
|
|
5
|
Wellington Management Group
Boston,
Massachusetts
|
$144M
|
+$63.9M
|
+1,224,573
|
+74%
|
|
|
6
|
|
$130M
|
+$14.9M
|
+286,198
|
+12%
|
|
|
7
|
Paradigm Biocapital Advisors
New York
|
$123M
|
+$22.7M
|
+435,103
|
+22%
|
|
|
8
|
Franklin Resources
San Mateo,
California
|
$118M
|
+$7.85M
|
+150,341
|
+7%
|
|
|
9
|
Federated Hermes
Pittsburgh,
Pennsylvania
|
$100M
|
-$20.5M
|
-392,000
|
-16%
|
|
|
10
|
Boxer Capital
San Diego,
California
|
$94.9M
|
–
|
–
|
–
|
|
|
11
|
Lynx1 Capital Management
San Juan,
Puerto Rico
|
$89.6M
|
+$30.7M
|
+587,159
|
+49%
|
|
|
12
|
|
$82.2M
|
+$6.25M
|
+119,660
|
+8%
|
|
|
13
|
Holocene Advisors
New York
|
$81.8M
|
+$3.35M
|
+64,122
|
+4%
|
|
|
14
|
Driehaus Capital Management
Chicago,
Illinois
|
$67.9M
|
-$9.97M
|
-191,041
|
-12%
|
|
|
15
|
Avoro Capital Advisors
New York
|
$67.7M
|
–
|
–
|
–
|
|
|
16
|
|
$67.4M
|
-$7.93M
|
-151,831
|
-10%
|
|
|
17
|
T. Rowe Price Associates
Baltimore,
Maryland
|
$64M
|
-$5.39M
|
-103,236
|
-7%
|
|
|
18
|
Polar Capital Holdings
London,
United Kingdom
|
$63.3M
|
–
|
–
|
–
|
|
|
19
|
Woodline Partners
San Francisco,
California
|
$59.2M
|
+$11.8M
|
+226,156
|
+24%
|
|
|
20
|
Marshall Wace
London,
United Kingdom
|
$56.1M
|
+$8.57M
|
+164,151
|
+17%
|
|
|
21
|
Pictet Asset Management
Carouge,
Switzerland
|
$50.6M
|
+$8.77M
|
+167,974
|
+20%
|
|
|
22
|
|
$45.4M
|
-$18.5M
|
-355,251
|
-28%
|
|
|
23
|
Rock Springs Capital Management
Baltimore,
Maryland
|
$44.6M
|
-$5.67M
|
-108,524
|
-11%
|
|
|
24
|
T. Rowe Price Investment Management
Baltimore,
Maryland
|
$41.5M
|
+$5.72M
|
+109,592
|
+15%
|
|
|
25
|
|
$38.5M
|
+$3.29M
|
+63,006
|
+9%
|
|
