|
1
|
Fidelity Investments
Boston,
Massachusetts
|
$368M
|
+$221M
|
+4,562,387
|
+274%
|
|
|
2
|
|
$247M
|
+$2.91M
|
+60,000
|
+1%
|
|
|
3
|
Commodore Capital
New York
|
$189M
|
-$56.2M
|
-1,160,000
|
-27%
|
|
|
4
|
Deerfield Management
New York
|
$163M
|
+$4.84M
|
+100,000
|
+4%
|
|
|
5
|
Federated Hermes
Pittsburgh,
Pennsylvania
|
$142M
|
+$7.26M
|
+150,000
|
+7%
|
|
|
6
|
|
$138M
|
+$12M
|
+247,605
|
+12%
|
|
|
7
|
Franklin Resources
San Mateo,
California
|
$125M
|
+$11.3M
|
+232,915
|
+12%
|
|
|
8
|
Paradigm Biocapital Advisors
New York
|
$120M
|
+$97.8M
|
+2,019,814
|
New
|
|
|
9
|
Boxer Capital
San Diego,
California
|
$112M
|
–
|
–
|
–
|
|
|
10
|
Wellington Management Group
Boston,
Massachusetts
|
$98.4M
|
+$20.1M
|
+414,301
|
+33%
|
|
|
11
|
Holocene Advisors
New York
|
$93.1M
|
+$30.7M
|
+634,290
|
+68%
|
|
|
12
|
Driehaus Capital Management
Chicago,
Illinois
|
$91.7M
|
+$15.7M
|
+323,518
|
+26%
|
|
|
13
|
|
$90.3M
|
+$2.8M
|
+57,825
|
+4%
|
|
|
14
|
|
$88.9M
|
+$25.4M
|
+523,795
|
+54%
|
|
|
15
|
T. Rowe Price Associates
Baltimore,
Maryland
|
$82M
|
+$9.68M
|
+199,862
|
+17%
|
|
|
16
|
Avoro Capital Advisors
New York
|
$80.2M
|
+$22.6M
|
+466,112
|
+52%
|
|
|
17
|
BVF Inc
San Francisco,
California
|
$75.7M
|
+$5.17M
|
+106,800
|
+9%
|
|
|
18
|
Polar Capital Holdings
London,
United Kingdom
|
$75M
|
+$61.4M
|
+1,267,052
|
New
|
|
|
19
|
|
$74.7M
|
-$25.5M
|
-527,000
|
-29%
|
|
|
20
|
Lynx1 Capital Management
San Juan,
Puerto Rico
|
$71.4M
|
-$14.6M
|
-302,300
|
-20%
|
|
|
21
|
Janus Henderson Group
London,
|
$60.2M
|
+$23M
|
+474,427
|
+87%
|
|
|
22
|
Rock Springs Capital Management
Baltimore,
Maryland
|
$59.2M
|
-$7.05M
|
-145,487
|
-13%
|
|
|
23
|
Woodline Partners
San Francisco,
California
|
$56.7M
|
+$13.9M
|
+287,970
|
+43%
|
|
|
24
|
Marshall Wace
London,
United Kingdom
|
$56.7M
|
+$41.3M
|
+853,060
|
+813%
|
|
|
25
|
Logos Global Management
San Francisco,
California
|
$50.3M
|
+$41.2M
|
+850,000
|
New
|
|
