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Monopar Therapeutics

56 hedge funds and large institutions have $354M invested in Monopar Therapeutics in 2025 Q3 according to their latest regulatory filings, with 16 funds opening new positions, 18 increasing their positions, 15 reducing their positions, and 3 closing their positions.

New
Increased
Maintained
Reduced
Closed

433% more first-time investments, than exits

New positions opened: 16 | Existing positions closed: 3

213% more capital invested

Capital invested by funds: $113M → $354M (+$241M)

30% more funds holding

Funds holding: 4356 (+13)

20% more repeat investments, than reductions

Existing positions increased: 18 | Existing positions reduced: 15

18.33% more ownership

Funds ownership: 51.94%70.28% (+18%)

Holders
56
Holders Change
+13
Holders Change %
+30.23%
% of All Funds
0.73%
Holding in Top 10
1
Holding in Top 10 Change
+1
Holding in Top 10 Change %
% of All Funds
0.01%
New
16
Increased
18
Reduced
15
Closed
3
Calls
Puts
Net Calls
Net Calls Change
Name Holding Trade Value Shares
Change
Change in
Stake
Janus Henderson Group
1
Janus Henderson Group
United Kingdom
$105M +$5.14M +115,000 +10%
Adage Capital Partners
2
Adage Capital Partners
Massachusetts
$53.8M +$2.68M +60,000 +10%
RCM
3
RA Capital Management
Massachusetts
$41.8M
Wellington Management Group
4
Wellington Management Group
Massachusetts
$18.9M +$10.3M +231,463 New
Vanguard Group
5
Vanguard Group
Pennsylvania
$17M +$5.44M +121,729 +141%
BlackRock
6
BlackRock
New York
$16.6M -$63.4K -1,418 -0.7%
DM
7
Deerfield Management
New York
$13M +$7.14M +159,765 New
SVCM
8
Saturn V Capital Management
Texas
$12.7M +$6.95M +155,370 New
TCM
9
TCG Crossover Management
California
$12.5M +$6.84M +153,000 New
ACM
10
ADAR1 Capital Management
Texas
$10.6M +$1.3M +29,025 +29%
VC
11
Vivo Capital
California
$7.39M +$4.05M +90,500 New
Geode Capital Management
12
Geode Capital Management
Massachusetts
$6.94M -$535K -11,958 -12%
AAA
13
Affinity Asset Advisors
New York
$6.49M +$536K +11,983 +18%
State Street
14
State Street
Massachusetts
$5.9M +$1.36M +30,412 +73%
DCM
15
Driehaus Capital Management
Illinois
$5.28M +$2.89M +64,636 New
ABG
16
Ally Bridge Group
New York
$5.26M +$1.34M +29,918 +87%
Northern Trust
17
Northern Trust
Illinois
$2.19M -$222K -4,958 -16%
Bank of New York Mellon
18
Bank of New York Mellon
New York
$1.4M +$368K +8,222 +92%
Morgan Stanley
19
Morgan Stanley
New York
$1.28M +$348K +7,779 +98%
Barclays
20
Barclays
United Kingdom
$1.23M +$349K +7,797 +107%
EI
21
EAM Investors
California
$1.19M +$654K +14,629 New
Alyeska Investment Group
22
Alyeska Investment Group
Illinois
$998K +$546K +12,215 New
Charles Schwab
23
Charles Schwab
California
$963K -$64.9K -1,452 -11%
UBS Group
24
UBS Group
Switzerland
$651K -$621K -13,900 -64%
Millennium Management
25
Millennium Management
New York
$599K -$333K -7,455 -50%

MNPR Hedge Fund Activity: Q3 2025 in Review

56 of the 7,621 institutional investors tracked by Wall St. Rank reported a position in Monopar Therapeutics (MNPR) for Q3 2025, worth a combined $354M — up 213% from $113M a quarter earlier.

Buyers outnumbered sellers: 16 funds opened new MNPR positions and 3 closed out — a net gain of 13 holders — while 18 added to existing stakes and 15 trimmed.

The largest buyer was Wellington Management Group, opening a new position worth an estimated $10.3M. The largest seller was Point72 Asset Management, exiting entirely with an estimated $3.72M sold.

  • 56 institutional investors held Monopar Therapeutics (MNPR) as of Q3 2025, up from 43 in Q2 2025.
  • Funds reported $354M of Monopar Therapeutics stock for Q3 2025, up 213% quarter-over-quarter.
  • 16 funds opened new Monopar Therapeutics positions in Q3 2025 and 3 closed out, a net change of +13 holders.
  • The largest Monopar Therapeutics buyer in Q3 2025 was Wellington Management Group, an estimated $10.3M added.
  • The largest Monopar Therapeutics seller in Q3 2025 was Point72 Asset Management, an estimated $3.72M sold.

Based on aggregated 13F filings for Q3 2025.