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Monopar Therapeutics
MNPR

43 hedge funds and large institutions have $113M invested in Monopar Therapeutics in 2025 Q2 according to their latest regulatory filings, with 19 funds opening new positions, 15 increasing their positions, 4 reducing their positions, and 11 closing their positions.

New
Increased
Maintained
Reduced
Closed

275% more repeat investments, than reductions

Existing positions increased: 15 | Existing positions reduced: 4

73% more first-time investments, than exits

New positions opened: 19 | Existing positions closed: 11

23% more funds holding

Funds holding: 35 → 43 (+8)

4.63% more ownership

Funds ownership: 47.31% → 51.94% (+4.6%)

4% more capital invested

Capital invested by funds: $109M → $113M (+$3.93M)

Holders
43
Holders Change
+8
Holders Change %
+22.86%
% of All Funds
0.57%
Holding in Top 10
–
Holding in Top 10 Change
–
Holding in Top 10 Change %
–
% of All Funds
–
New
19
Increased
15
Reduced
4
Closed
11
Calls
–
Puts
–
Net Calls
–
Net Calls Change
–

Top Buyers

Rank Fund Capital Flow
1
BlackRock
BlackRock
New York
+$6.93M
2
Geode Capital Management
Geode Capital Management
Massachusetts
+$1.76M
3
Janus Henderson Group
Janus Henderson Group
United Kingdom
+$1.38M
4
ABG
Ally Bridge Group
New York
+$1.25M
5
Vanguard Group
Vanguard Group
Pennsylvania
+$1.14M

Top Sellers

Rank Fund Capital Flow
1
Point72 Asset Management
Point72 Asset Management
Connecticut
-$2.33M
2
Millennium Management
Millennium Management
New York
-$1.66M
3
Marshall Wace
Marshall Wace
United Kingdom
-$946K
4
Goldman Sachs
Goldman Sachs
New York
-$673K
5
Jane Street
Jane Street
New York
-$377K
Name Holding Trade Value Shares
Change 		Change in
Stake
Janus Henderson Group
1
Janus Henderson Group
United Kingdom
$41.6M +$1.38M +37,962 +3%
Adage Capital Partners
2
Adage Capital Partners
Massachusetts
$21.4M – – –
RCM
3
RA Capital Management
Massachusetts
$18.3M – – –
BlackRock
4
BlackRock
New York
$7.34M +$6.93M +190,705 +1,318%
Point72 Asset Management
5
Point72 Asset Management
Connecticut
$3.72M -$2.33M -64,141 -38%
ACM
6
ADAR1 Capital Management
Texas
$3.61M +$7.26K +200 +0.2%
Geode Capital Management
7
Geode Capital Management
Massachusetts
$3.47M +$1.76M +48,379 +100%
Vanguard Group
8
Vanguard Group
Pennsylvania
$3.09M +$1.14M +31,255 +57%
AAA
9
Affinity Asset Advisors
New York
$2.42M +$200K +5,500 +9%
State Street
10
State Street
Massachusetts
$1.5M +$945K +26,012 +164%
ABG
11
Ally Bridge Group
New York
$1.24M +$1.25M +34,537 New
Northern Trust
12
Northern Trust
Illinois
$1.14M +$823K +22,652 +247%
UBS Group
13
UBS Group
Switzerland
$783K +$499K +13,752 +169%
Millennium Management
14
Millennium Management
New York
$529K -$1.66M -45,578 -76%
Charles Schwab
15
Charles Schwab
California
$474K +$481K +13,249 New
Bank of New York Mellon
16
Bank of New York Mellon
New York
$320K +$325K +8,948 New
Susquehanna International Group
17
Susquehanna International Group
Pennsylvania
$299K +$303K +8,356 New
Morgan Stanley
18
Morgan Stanley
New York
$284K +$236K +6,508 +457%
Barclays
19
Barclays
United Kingdom
$261K +$264K +7,273 +60,608%
Citadel Advisors
20
Citadel Advisors
Florida
$223K +$226K +6,232 New
RhumbLine Advisers
21
RhumbLine Advisers
Massachusetts
$209K +$212K +5,850 New
GL
22
Gerber LLC
Ohio
$200K – – –
Deutsche Bank
23
Deutsche Bank
Germany
$121K +$123K +3,385 New
New York State Common Retirement Fund
24
New York State Common Retirement Fund
New York
$104K +$105K +2,900 New
MIM
25
MetLife Investment Management
New Jersey
$90.8K +$92.2K +2,538 New
1
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MNPR Hedge Fund Activity: Q2 2025 in Review

43 of the 7,596 institutional investors tracked by Wall St. Rank reported a position in Monopar Therapeutics (MNPR) for Q2 2025, worth a combined $113M — up 3.6% from $109M a quarter earlier.

Buyers outnumbered sellers: 19 funds opened new MNPR positions and 11 closed out — a net gain of 8 holders — while 15 added to existing stakes and 4 trimmed.

The largest buyer was BlackRock, adding an estimated $6.93M. The largest seller was Point72 Asset Management, cutting an estimated $2.33M.

  • 43 institutional investors held Monopar Therapeutics (MNPR) as of Q2 2025, up from 35 in Q1 2025.
  • Funds reported $113M of Monopar Therapeutics stock for Q2 2025, up 3.6% quarter-over-quarter.
  • 19 funds opened new Monopar Therapeutics positions in Q2 2025 and 11 closed out, a net change of +8 holders.
  • The largest Monopar Therapeutics buyer in Q2 2025 was BlackRock, an estimated $6.93M added.
  • The largest Monopar Therapeutics seller in Q2 2025 was Point72 Asset Management, an estimated $2.33M sold.

Based on aggregated 13F filings for Q2 2025.