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Mineralys Therapeutics

224 hedge funds and large institutions have $2.69B invested in Mineralys Therapeutics in 2026 Q2 according to their latest regulatory filings, with 36 funds opening new positions, 88 increasing their positions, 65 reducing their positions, and 22 closing their positions.

New
Increased
Maintained
Reduced
Closed

64% more first-time investments, than exits

New positions opened: 36 | Existing positions closed: 22

41% more call options, than puts

Call options by funds: $46.4M | Put options by funds: $33M

35% more repeat investments, than reductions

Existing positions increased: 88 | Existing positions reduced: 65

11.11% more ownership

Funds ownership: 109.62%120.72% (+11%)

9% more capital invested

Capital invested by funds: $2.46B → $2.69B (+$232M)

5% more funds holding

Funds holding: 214224 (+10)

10% less funds holding in top 10

Funds holding in top 10: 109 (-1)

Holders
224
Holders Change
+10
Holders Change %
+4.67%
% of All Funds
2.71%
Holding in Top 10
9
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-10%
% of All Funds
0.11%
New
36
Increased
88
Reduced
65
Closed
22
Calls
$46.4M
Puts
$33M
Net Calls
+$13.4M
Net Calls Change
+$17.8M
Name Holding Trade Value Shares
Change
Change in
Stake
SG Americas Securities
101
SG Americas Securities
New York
$1.65M -$4.52M -164,870 -73%
Man Group
102
Man Group
United Kingdom
$1.61M +$1.36M +49,501 +488%
DZ Bank
103
DZ Bank
Germany
$1.6M
Deutsche Bank
104
Deutsche Bank
Germany
$1.59M +$515K +18,761 +47%
DP
105
Diadema Partners
New Jersey
$1.52M +$823K +30,000 +114%
JP Morgan Chase
106
JP Morgan Chase
New York
$1.4M -$63.3K -2,307 -4%
Canada Pension Plan Investment Board
107
Canada Pension Plan Investment Board
Ontario, Canada
$1.39M
XT
108
XTX Topco
Cayman Islands
$1.29M -$569K -20,754 -30%
EAM
109
Erste Asset Management
Austria
$1.21M
DCM
110
DAFNA Capital Management
California
$1.2M +$165K +6,000 +16%
PA
111
Profund Advisors
Maryland
$1.06M -$75.7K -2,759 -7%
Vanguard Asset Management
112
Vanguard Asset Management
$1.06M +$273K +9,934 +34%
Legal & General Group
113
Legal & General Group
United Kingdom
$1.03M -$11.6K -423 -1%
Simplex Trading
114
Simplex Trading
Illinois
$971K +$450K +16,417 +84%
Mirae Asset Global ETFs Holdings
115
Mirae Asset Global ETFs Holdings
Hong Kong
$957K +$174K +6,325 +22%
Verition Fund Management
116
Verition Fund Management
Connecticut
$937K -$1.66M -60,390 -63%
Victory Capital Management
117
Victory Capital Management
Texas
$914K +$20.4K +742 +2%
WG
118
Winton Group
United Kingdom
$912K +$927K +33,800 New
MIM
119
MetLife Investment Management
New Jersey
$911K +$190K +6,929 +26%
Manulife (Manufacturers Life Insurance)
120
Manulife (Manufacturers Life Insurance)
Ontario, Canada
$864K +$154K +5,596 +21%
MF
121
Magnetar Financial
Illinois
$818K +$323K +11,788 +64%
GCM
122
Greenland Capital Management
New York
$809K -$755K -27,500 -48%
QCM
123
Quantinno Capital Management
New York
$799K +$249K +9,088 +44%
Creative Planning
124
Creative Planning
Kansas
$788K +$135K +4,914 +20%
JT
125
Jupiter Topco
New York
$773K +$786K +28,648 New

MLYS Hedge Fund Activity: Q2 2026 in Review

224 of the 8,274 institutional investors tracked by Wall St. Rank reported a position in Mineralys Therapeutics (MLYS) for Q2 2026, worth a combined $2.69B — up 9.5% from $2.46B a quarter earlier.

Buyers outnumbered sellers: 36 funds opened new MLYS positions and 22 closed out — a net gain of 14 holders — while 88 added to existing stakes and 65 trimmed.

The largest buyer was Deerfield Management, opening a new position worth an estimated $109M. The largest seller was Caligan Partners, exiting entirely with an estimated $75.1M sold.

  • 224 institutional investors held Mineralys Therapeutics (MLYS) as of Q2 2026, up from 214 in Q1 2026.
  • Funds reported $2.69B of Mineralys Therapeutics stock for Q2 2026, up 9.5% quarter-over-quarter.
  • 36 funds opened new Mineralys Therapeutics positions in Q2 2026 and 22 closed out, a net change of +14 holders.
  • The largest Mineralys Therapeutics buyer in Q2 2026 was Deerfield Management, an estimated $109M added.
  • The largest Mineralys Therapeutics seller in Q2 2026 was Caligan Partners, an estimated $75.1M sold.

Based on aggregated 13F filings for Q2 2026.