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Mineralys Therapeutics

224 hedge funds and large institutions have $2.69B invested in Mineralys Therapeutics in 2026 Q2 according to their latest regulatory filings, with 36 funds opening new positions, 88 increasing their positions, 65 reducing their positions, and 22 closing their positions.

New
Increased
Maintained
Reduced
Closed

64% more first-time investments, than exits

New positions opened: 36 | Existing positions closed: 22

41% more call options, than puts

Call options by funds: $46.4M | Put options by funds: $33M

35% more repeat investments, than reductions

Existing positions increased: 88 | Existing positions reduced: 65

11.11% more ownership

Funds ownership: 109.62%120.72% (+11%)

9% more capital invested

Capital invested by funds: $2.46B → $2.69B (+$232M)

5% more funds holding

Funds holding: 214224 (+10)

10% less funds holding in top 10

Funds holding in top 10: 109 (-1)

Holders
224
Holders Change
+10
Holders Change %
+4.67%
% of All Funds
2.71%
Holding in Top 10
9
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-10%
% of All Funds
0.11%
New
36
Increased
88
Reduced
65
Closed
22
Calls
$46.4M
Puts
$33M
Net Calls
+$13.4M
Net Calls Change
+$17.8M
Name Holding Trade Value Shares
Change
Change in
Stake
Russell Investments Group
76
Russell Investments Group
United Kingdom
$3.46M -$2.06M -75,257 -37%
VOYA Investment Management
77
VOYA Investment Management
Georgia
$3.4M -$2.47M -90,098 -42%
Ensign Peak Advisors
78
Ensign Peak Advisors
Utah
$3.19M +$170K +6,192 +6%
2L
79
22NW LP
Washington
$3.07M -$9.07M -330,485 -74%
Swiss National Bank
80
Swiss National Bank
Switzerland
$3.01M +$590K +21,500 +24%
II
81
Ishara Investments
California
$2.77M +$562K +20,500 +25%
MAM
82
Mark Asset Management
New York
$2.73M -$1.2M -43,586 -30%
ECM
83
ExodusPoint Capital Management
New York
$2.73M +$2.77M +101,052 New
TGY2IT
84
Timothy G. Youngquist 2020 Irrevocable Trust
Florida
$2.72M +$2.77M +100,869 New
Citigroup
85
Citigroup
New York
$2.68M +$2.31M +84,247 +558%
SSA
86
Schonfeld Strategic Advisors
New York
$2.57M -$2.26M -82,343 -46%
AA
87
ALPS Advisors
Colorado
$2.4M +$674K +24,557 +38%
Squarepoint
88
Squarepoint
New York
$2.33M -$526K -19,164 -18%
HS
89
HighVista Strategies
Massachusetts
$2.32M +$1.08M +39,307 +84%
BCM
90
BlueCrest Capital Management
Jersey
$2.3M +$2.34M +85,157 New
KCA
91
KVP Capital Advisors
California
$2.27M +$2.31M +84,168 New
UBS AM
92
UBS AM
Illinois
$2.14M -$9.27K -338 -0.4%
Rafferty Asset Management
93
Rafferty Asset Management
New York
$2.11M -$444K -16,172 -17%
State of Wisconsin Investment Board
94
State of Wisconsin Investment Board
Wisconsin
$1.98M +$250K +9,127 +14%
RhumbLine Advisers
95
RhumbLine Advisers
Massachusetts
$1.89M +$350K +12,761 +22%
HWAM
96
Hennion & Walsh Asset Management
New Jersey
$1.88M -$16.7K -609 -0.9%
HF
97
HRT Financial
New York
$1.85M -$751K -27,355 -29%
Wells Fargo
98
Wells Fargo
California
$1.78M +$1.1M +39,976 +153%
PHS
99
PFM Health Sciences
California
$1.68M -$2.2M -80,259 -56%
Barclays
100
Barclays
United Kingdom
$1.65M +$749K +27,313 +81%

MLYS Hedge Fund Activity: Q2 2026 in Review

224 of the 8,274 institutional investors tracked by Wall St. Rank reported a position in Mineralys Therapeutics (MLYS) for Q2 2026, worth a combined $2.69B — up 9.5% from $2.46B a quarter earlier.

Buyers outnumbered sellers: 36 funds opened new MLYS positions and 22 closed out — a net gain of 14 holders — while 88 added to existing stakes and 65 trimmed.

The largest buyer was Deerfield Management, opening a new position worth an estimated $109M. The largest seller was Caligan Partners, exiting entirely with an estimated $75.1M sold.

  • 224 institutional investors held Mineralys Therapeutics (MLYS) as of Q2 2026, up from 214 in Q1 2026.
  • Funds reported $2.69B of Mineralys Therapeutics stock for Q2 2026, up 9.5% quarter-over-quarter.
  • 36 funds opened new Mineralys Therapeutics positions in Q2 2026 and 22 closed out, a net change of +14 holders.
  • The largest Mineralys Therapeutics buyer in Q2 2026 was Deerfield Management, an estimated $109M added.
  • The largest Mineralys Therapeutics seller in Q2 2026 was Caligan Partners, an estimated $75.1M sold.

Based on aggregated 13F filings for Q2 2026.