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Mineralys Therapeutics

224 hedge funds and large institutions have $2.69B invested in Mineralys Therapeutics in 2026 Q2 according to their latest regulatory filings, with 36 funds opening new positions, 88 increasing their positions, 65 reducing their positions, and 22 closing their positions.

New
Increased
Maintained
Reduced
Closed

64% more first-time investments, than exits

New positions opened: 36 | Existing positions closed: 22

41% more call options, than puts

Call options by funds: $46.4M | Put options by funds: $33M

35% more repeat investments, than reductions

Existing positions increased: 88 | Existing positions reduced: 65

11.11% more ownership

Funds ownership: 109.62%120.72% (+11%)

9% more capital invested

Capital invested by funds: $2.46B → $2.69B (+$232M)

5% more funds holding

Funds holding: 214224 (+10)

10% less funds holding in top 10

Funds holding in top 10: 109 (-1)

Holders
224
Holders Change
+10
Holders Change %
+4.67%
% of All Funds
2.71%
Holding in Top 10
9
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-10%
% of All Funds
0.11%
New
36
Increased
88
Reduced
65
Closed
22
Calls
$46.4M
Puts
$33M
Net Calls
+$13.4M
Net Calls Change
+$17.8M
Name Holding Trade Value Shares
Change
Change in
Stake
RPAM
51
Rhenman & Partners Asset Management
Sweden
$11.2M +$4.21M +153,300 +58%
CM
52
Caption Management
Oklahoma
$11.1M +$11.3M +413,087 New
Jennison Associates
53
Jennison Associates
New York
$10.3M -$24.2M -883,427 -70%
PHP
54
Parkman Healthcare Partners
Connecticut
$10.3M +$5.95K +217 +0.1%
Renaissance Technologies
55
Renaissance Technologies
New York
$10.2M -$123K -4,500 -1%
CP
56
CenterBook Partners
Connecticut
$9.86M +$7.58M +276,300 +309%
UBS Group
57
UBS Group
Switzerland
$9.76M +$7.23M +263,567 +269%
Susquehanna International Group
58
Susquehanna International Group
Pennsylvania
$9.59M +$9.32M +339,800 +2,155%
D.E. Shaw & Co
59
D.E. Shaw & Co
New York
$9.52M -$14.7M -534,463 -60%
EP
60
Eversept Partners
New York
$8.36M +$8.5M +309,689 New
Schroder Investment Management Group
61
Schroder Investment Management Group
United Kingdom
$8.26M +$4.85M +176,622 +135%
ACM
62
ADAR1 Capital Management
Texas
$8.06M +$3.96M +144,200 +93%
LP
63
Longaeva Partners
Illinois
$7.58M +$7.71M +281,104 New
Nuveen
64
Nuveen
North Carolina
$7.42M +$4.47M +162,836 +145%
Qube Research & Technologies (QRT)
65
Qube Research & Technologies (QRT)
United Kingdom
$6.74M -$18.2M -664,952 -73%
TCM
66
TimesSquare Capital Management
New York
$6.36M -$2.82M -102,940 -30%
SCM
67
Suvretta Capital Management
New York
$4.69M -$37.4M -1,364,776 -89%
TI
68
Trexquant Investment
Connecticut
$4.58M +$3.09M +112,515 +197%
Two Sigma Investments
69
Two Sigma Investments
New York
$4.37M -$4.1M -149,406 -48%
Bank of New York Mellon
70
Bank of New York Mellon
New York
$4.28M +$784K +28,586 +22%
BHCM
71
Brevan Howard Capital Management
Jersey
$4.15M +$1.72M +62,793 +69%
AQR Capital Management
72
AQR Capital Management
Connecticut
$4.11M +$93.8K +3,418 +2%
BGM
73
Burkehill Global Management
New York
$4.05M
BFM
74
Boothbay Fund Management
New York
$3.98M -$23.4M -854,326 -85%
AGP
75
Artia Global Partners
Florida
$3.72M

MLYS Hedge Fund Activity: Q2 2026 in Review

224 of the 8,274 institutional investors tracked by Wall St. Rank reported a position in Mineralys Therapeutics (MLYS) for Q2 2026, worth a combined $2.69B — up 9.5% from $2.46B a quarter earlier.

Buyers outnumbered sellers: 36 funds opened new MLYS positions and 22 closed out — a net gain of 14 holders — while 88 added to existing stakes and 65 trimmed.

The largest buyer was Deerfield Management, opening a new position worth an estimated $109M. The largest seller was Caligan Partners, exiting entirely with an estimated $75.1M sold.

  • 224 institutional investors held Mineralys Therapeutics (MLYS) as of Q2 2026, up from 214 in Q1 2026.
  • Funds reported $2.69B of Mineralys Therapeutics stock for Q2 2026, up 9.5% quarter-over-quarter.
  • 36 funds opened new Mineralys Therapeutics positions in Q2 2026 and 22 closed out, a net change of +14 holders.
  • The largest Mineralys Therapeutics buyer in Q2 2026 was Deerfield Management, an estimated $109M added.
  • The largest Mineralys Therapeutics seller in Q2 2026 was Caligan Partners, an estimated $75.1M sold.

Based on aggregated 13F filings for Q2 2026.