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MoonLake Immunotherapeutics

134 hedge funds and large institutions have $270M invested in MoonLake Immunotherapeutics in 2025 Q3 according to their latest regulatory filings, with 49 funds opening new positions, 33 increasing their positions, 41 reducing their positions, and 45 closing their positions.

New
Increased
Maintained
Reduced
Closed

130% more call options, than puts

Call options by funds: $33.1M | Put options by funds: $14.4M

3% more funds holding

Funds holding: 130134 (+4)

9% more first-time investments, than exits

New positions opened: 49 | Existing positions closed: 45

20% less repeat investments, than reductions

Existing positions increased: 33 | Existing positions reduced: 41

33.32% less ownership

Funds ownership: 92.59%59.27% (-33%)

83% less funds holding in top 10

Funds holding in top 10: 61 (-5)

90% less capital invested

Capital invested by funds: $2.77B → $270M (-$2.5B)

Holders
134
Holders Change
+4
Holders Change %
+3.08%
% of All Funds
1.76%
Holding in Top 10
1
Holding in Top 10 Change
-5
Holding in Top 10 Change %
-83.33%
% of All Funds
0.01%
New
49
Increased
33
Reduced
41
Closed
45
Calls
$33.1M
Puts
$14.4M
Net Calls
+$18.7M
Net Calls Change
+$16.8M
Name Holding Trade Value Shares
Change
Change in
Stake
BI
1
BVF Inc
California
$142M
ACA
2
Avoro Capital Advisors
New York
$14.3M -$112M -2,150,000 -52%
CAM
3
Cormorant Asset Management
Massachusetts
$14.3M -$339M -6,499,978 -77%
Balyasny Asset Management
4
Balyasny Asset Management
Illinois
$12.2M +$66.5M +1,276,065 +302%
Adage Capital Partners
5
Adage Capital Partners
Massachusetts
$10.8M +$78.2M +1,500,000 New
SSA
6
Schonfeld Strategic Advisors
New York
$6.92M +$50.3M +965,405 New
T. Rowe Price Associates
7
T. Rowe Price Associates
Maryland
$5.9M -$93.3M -1,790,276 -69%
Fidelity Investments
8
Fidelity Investments
Massachusetts
$5.21M -$261M -5,003,617 -87%
N
9
Nuveen
North Carolina
$4.56M -$8.12M -155,856 -20%
Two Sigma Investments
10
Two Sigma Investments
New York
$3.26M +$23.7M +454,268 New
IC
11
Ikarian Capital
Texas
$3.12M +$22.7M +435,839 New
Goldman Sachs
12
Goldman Sachs
New York
$2.6M -$47.6M -912,698 -72%
Marshall Wace
13
Marshall Wace
United Kingdom
$2.3M -$10.8M -208,102 -39%
Verition Fund Management
14
Verition Fund Management
Connecticut
$1.96M +$13M +249,241 +1,059%
FTM
15
First Turn Management
California
$1.88M +$13.7M +262,643 New
BFM
16
Boothbay Fund Management
New York
$1.86M +$13.5M +258,779 New
Morgan Stanley
17
Morgan Stanley
New York
$1.84M +$11.1M +213,416 +494%
BCM
18
Boxer Capital Management
California
$1.79M +$13M +250,000 New
RPAM
19
Rhenman & Partners Asset Management
Sweden
$1.48M +$8.44M +162,000 +360%
Susquehanna International Group
20
Susquehanna International Group
Pennsylvania
$1.4M +$10.1M +194,741 New
DC
21
Decheng Capital
California
$1.3M
EAM
22
Exome Asset Management
New York
$1.28M +$9.28M +178,084 New
JP Morgan Chase
23
JP Morgan Chase
New York
$1.25M +$7.02M +134,764 +342%
Schroder Investment Management Group
24
Schroder Investment Management Group
United Kingdom
$1.22M +$9.18M +176,100 +908%
ACM
25
ADAR1 Capital Management
Texas
$1.09M +$6.11M +117,181 +341%

MLTX Hedge Fund Activity: Q3 2025 in Review

134 of the 7,620 institutional investors tracked by Wall St. Rank reported a position in MoonLake Immunotherapeutics (MLTX) for Q3 2025, worth a combined $270M — down 90% from $2.77B a quarter earlier.

Buyers outnumbered sellers: 49 funds opened new MLTX positions and 45 closed out — a net gain of 4 holders — while 33 added to existing stakes and 41 trimmed.

The largest buyer was Adage Capital Partners, opening a new position worth an estimated $78.2M. The largest seller was Cormorant Asset Management, cutting an estimated $339M.

  • 134 institutional investors held MoonLake Immunotherapeutics (MLTX) as of Q3 2025, up from 130 in Q2 2025.
  • Funds reported $270M of MoonLake Immunotherapeutics stock for Q3 2025, down 90% quarter-over-quarter.
  • 49 funds opened new MoonLake Immunotherapeutics positions in Q3 2025 and 45 closed out, a net change of +4 holders.
  • The largest MoonLake Immunotherapeutics buyer in Q3 2025 was Adage Capital Partners, an estimated $78.2M added.
  • The largest MoonLake Immunotherapeutics seller in Q3 2025 was Cormorant Asset Management, an estimated $339M sold.

Based on aggregated 13F filings for Q3 2025.