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MoonLake Immunotherapeutics

130 hedge funds and large institutions have $2.77B invested in MoonLake Immunotherapeutics in 2025 Q2 according to their latest regulatory filings, with 23 funds opening new positions, 37 increasing their positions, 52 reducing their positions, and 27 closing their positions.

New
Increased
Maintained
Reduced
Closed

19% more capital invested

Capital invested by funds: $2.34B → $2.77B (+$434M)

5% more call options, than puts

Call options by funds: $39.6M | Put options by funds: $37.7M

0% more funds holding in top 10

Funds holding in top 10: 66 (0)

2.06% less ownership

Funds ownership: 94.65%92.59% (-2.1%)

4% less funds holding

Funds holding: 136130 (-6)

15% less first-time investments, than exits

New positions opened: 23 | Existing positions closed: 27

29% less repeat investments, than reductions

Existing positions increased: 37 | Existing positions reduced: 52

Holders
130
Holders Change
-6
Holders Change %
-4.41%
% of All Funds
1.71%
Holding in Top 10
6
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
0.08%
New
23
Increased
37
Reduced
52
Closed
27
Calls
$39.6M
Puts
$37.7M
Net Calls
+$1.9M
Net Calls Change
-$10.4M
Name Holding Trade Value Shares
Change
Change in
Stake
BI
1
BVF Inc
California
$932M
CAM
2
Cormorant Asset Management
Massachusetts
$401M
Fidelity Investments
3
Fidelity Investments
Massachusetts
$270M -$24.3M -596,465 -9%
ACA
4
Avoro Capital Advisors
New York
$196M +$56.2M +1,379,900 +50%
T. Rowe Price Associates
5
T. Rowe Price Associates
Maryland
$123M -$14.7M -360,597 -12%
Citadel Advisors
6
Citadel Advisors
Florida
$79M +$7.96M +195,406 +13%
Goldman Sachs
7
Goldman Sachs
New York
$60.2M -$694K -17,039 -1%
Westfield Capital Management
8
Westfield Capital Management
Massachusetts
$59.4M -$7.14M -175,394 -12%
Federated Hermes
9
Federated Hermes
Pennsylvania
$58.9M -$846K -20,778 -2%
AllianceBernstein
10
AllianceBernstein
Tennessee
$53.7M +$7M +171,932 +18%
PBA
11
Paradigm Biocapital Advisors
New York
$41.5M +$10.2M +250,900 +40%
N
12
Nuveen
North Carolina
$37.4M +$4.82M +118,212 +18%
RI
13
RTW Investments
New York
$35M +$30.2M +741,090 New
HRCM
14
Hood River Capital Management
Florida
$31.9M +$508K +12,462 +2%
VPC
15
Vestal Point Capital
New York
$26M +$14.3M +350,000 +175%
Marshall Wace
16
Marshall Wace
United Kingdom
$25M -$4.55M -111,706 -17%
SL
17
Siren LLC
Connecticut
$24M +$20.7M +508,267 New
Balyasny Asset Management
18
Balyasny Asset Management
Illinois
$20M +$14M +344,335 +437%
BlackRock
19
BlackRock
New York
$15.5M +$1.68M +41,133 +14%
MB
20
MPM BioImpact
Massachusetts
$14.8M -$101K -2,478 -0.8%
WP
21
Woodline Partners
California
$14.7M +$589K +14,454 +5%
FAM
22
Fred Alger Management
New York
$14M -$14.1M -347,258 -54%
SVCM
23
Saturn V Capital Management
Texas
$13.7M -$2.16M -53,065 -15%
5VM
24
5AM Venture Management
California
$13.3M
PCH
25
Polar Capital Holdings
United Kingdom
$11.7M -$34.7M -852,500 -78%

MLTX Hedge Fund Activity: Q2 2025 in Review

130 of the 7,595 institutional investors tracked by Wall St. Rank reported a position in MoonLake Immunotherapeutics (MLTX) for Q2 2025, worth a combined $2.77B — up 19% from $2.34B a quarter earlier.

Sellers outnumbered buyers: 27 funds closed out of MLTX and 23 opened new positions — a net loss of 4 holders — while 52 trimmed existing stakes and 37 added.

The largest buyer was Avoro Capital Advisors, adding an estimated $56.2M. The largest seller was Polar Capital Holdings, cutting an estimated $34.7M.

  • 130 institutional investors held MoonLake Immunotherapeutics (MLTX) as of Q2 2025, down from 136 in Q1 2025.
  • Funds reported $2.77B of MoonLake Immunotherapeutics stock for Q2 2025, up 19% quarter-over-quarter.
  • 23 funds opened new MoonLake Immunotherapeutics positions in Q2 2025 and 27 closed out, a net change of -4 holders.
  • The largest MoonLake Immunotherapeutics buyer in Q2 2025 was Avoro Capital Advisors, an estimated $56.2M added.
  • The largest MoonLake Immunotherapeutics seller in Q2 2025 was Polar Capital Holdings, an estimated $34.7M sold.

Based on aggregated 13F filings for Q2 2025.