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MoonLake Immunotherapeutics

147 hedge funds and large institutions have $1.17B invested in MoonLake Immunotherapeutics in 2026 Q1 according to their latest regulatory filings, with 40 funds opening new positions, 49 increasing their positions, 43 reducing their positions, and 21 closing their positions.

New
Increased
Maintained
Reduced
Closed

265% more call options, than puts

Call options by funds: $34M | Put options by funds: $9.32M

90% more first-time investments, than exits

New positions opened: 40 | Existing positions closed: 21

58% more capital invested

Capital invested by funds: $743M → $1.17B (+$431M)

14% more repeat investments, than reductions

Existing positions increased: 49 | Existing positions reduced: 43

13% more funds holding

Funds holding: 130147 (+17)

0% more funds holding in top 10

Funds holding in top 10: 33 (0)

0.5% less ownership

Funds ownership: 88.47%87.97% (-0.5%)

Holders
147
Holders Change
+17
Holders Change %
+13.08%
% of All Funds
1.81%
Holding in Top 10
3
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
0.04%
New
40
Increased
49
Reduced
43
Closed
21
Calls
$34M
Puts
$9.32M
Net Calls
+$24.7M
Net Calls Change
+$770K
Name Holding Trade Value Shares
Change
Change in
Stake
Two Sigma Advisers
151
Two Sigma Advisers
New York
-$1.74M -131,700 Closed
Ameriprise
152
Ameriprise
Minnesota
-$1.73M -130,964 Closed
Walleye Trading
153
Walleye Trading
New York
-$1.15M -87,390 Closed
QC
154
Quadrature Capital
United Kingdom
-$662K -50,217 Closed
WP
155
Woodline Partners
California
-$648K -49,168 Closed
CCM
156
Cinctive Capital Management
New York
-$490K -37,194 Closed
AI
157
Axiom Investors
Connecticut
-$343K -25,998 Closed
BIG
158
Brooklyn Investment Group
New York
-$204K -14,920 Closed
CCIA
159
Campbell & Co Investment Adviser
Maryland
-$177K -13,448 Closed
CC
160
Centiva Capital
New York
-$204K -12,291 Closed
HSBC Holdings
161
HSBC Holdings
United Kingdom
-$147K -11,095 Closed
PAP
162
Persistent Asset Partners
Hong Kong
-$112K -8,523 Closed
T. Rowe Price Investment Management
163
T. Rowe Price Investment Management
Maryland
-$47K -3,557 Closed
KAS
164
Kestra Advisory Services
Texas
-$26.4K -2,000 Closed
ACM
165
ACT Capital Management
Pennsylvania
-$19.8K -1,500 Closed
TRCT
166
Tower Research Capital (TRC)
New York
-$9.28K -704 Closed
WA
167
WPG Advisers
Maryland
-$40 -3 Closed
IA
168
IFP Advisors
Florida
-$13 -1 Closed

MLTX Hedge Fund Activity: Q1 2026 in Review

147 of the 8,126 institutional investors tracked by Wall St. Rank reported a position in MoonLake Immunotherapeutics (MLTX) for Q1 2026, worth a combined $1.17B — up 58% from $743M a quarter earlier.

Buyers outnumbered sellers: 40 funds opened new MLTX positions and 21 closed out — a net gain of 19 holders — while 49 added to existing stakes and 43 trimmed.

The largest buyer was MPM BioImpact, opening a new position worth an estimated $30M. The largest seller was BVF Inc, cutting an estimated $62.1M.

  • 147 institutional investors held MoonLake Immunotherapeutics (MLTX) as of Q1 2026, up from 130 in Q4 2025.
  • Funds reported $1.17B of MoonLake Immunotherapeutics stock for Q1 2026, up 58% quarter-over-quarter.
  • 40 funds opened new MoonLake Immunotherapeutics positions in Q1 2026 and 21 closed out, a net change of +19 holders.
  • The largest MoonLake Immunotherapeutics buyer in Q1 2026 was MPM BioImpact, an estimated $30M added.
  • The largest MoonLake Immunotherapeutics seller in Q1 2026 was BVF Inc, an estimated $62.1M sold.

Based on aggregated 13F filings for Q1 2026.