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MoonLake Immunotherapeutics

147 hedge funds and large institutions have $1.17B invested in MoonLake Immunotherapeutics in 2026 Q1 according to their latest regulatory filings, with 40 funds opening new positions, 49 increasing their positions, 43 reducing their positions, and 21 closing their positions.

New
Increased
Maintained
Reduced
Closed

265% more call options, than puts

Call options by funds: $34M | Put options by funds: $9.32M

90% more first-time investments, than exits

New positions opened: 40 | Existing positions closed: 21

58% more capital invested

Capital invested by funds: $743M → $1.17B (+$431M)

14% more repeat investments, than reductions

Existing positions increased: 49 | Existing positions reduced: 43

13% more funds holding

Funds holding: 130147 (+17)

0% more funds holding in top 10

Funds holding in top 10: 33 (0)

0.5% less ownership

Funds ownership: 88.47%87.97% (-0.5%)

Holders
147
Holders Change
+17
Holders Change %
+13.08%
% of All Funds
1.81%
Holding in Top 10
3
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
0.04%
New
40
Increased
49
Reduced
43
Closed
21
Calls
$34M
Puts
$9.32M
Net Calls
+$24.7M
Net Calls Change
+$770K
Name Holding Trade Value Shares
Change
Change in
Stake
Mariner
76
Mariner
Kansas
$838K +$411K +24,791 +123%
Qube Research & Technologies (QRT)
77
Qube Research & Technologies (QRT)
United Kingdom
$800K +$711K +42,917 New
N
78
Nuveen
North Carolina
$623K -$10M -604,017 -95%
BHCM
79
Brevan Howard Capital Management
Jersey
$606K -$764K -46,131 -59%
California State Teachers Retirement System (CalSTRS)
80
California State Teachers Retirement System (CalSTRS)
California
$546K
SSA
81
Schonfeld Strategic Advisors
New York
$535K -$4.86M -293,579 -91%
Barclays
82
Barclays
United Kingdom
$515K -$375K -22,649 -45%
Dimensional Fund Advisors
83
Dimensional Fund Advisors
Texas
$490K -$2.6M -157,245 -86%
OF
84
Optimize Financial
California
$455K +$404K +24,419 New
VAM
85
Vanguard Asset Management
$444K +$395K +23,828 New
Group One Trading
86
Group One Trading
Illinois
$402K -$148K -8,913 -29%
QL
87
Quarry LP
New York
$396K +$352K +21,250 New
GCM
88
Graham Capital Management
Connecticut
$393K -$53.1K -3,203 -13%
Legal & General Group
89
Legal & General Group
United Kingdom
$383K +$74.2K +4,481 +28%
Northern Trust
90
Northern Trust
Illinois
$363K +$16.5K +998 +5%
AC
91
AXQ Capital
New Jersey
$359K +$319K +19,241 New
Zurich Cantonal Bank
92
Zurich Cantonal Bank
Switzerland
$358K +$93.4K +5,637 +41%
VIA
93
Virtus Investment Advisers
Connecticut
$344K +$7.44K +449 +2%
VA
94
Vident Advisory
Georgia
$339K +$45.8K +2,764 +18%
Acadian Asset Management
95
Acadian Asset Management
Massachusetts
$305K +$274K +16,527 New
Osaic Holdings
96
Osaic Holdings
Arizona
$296K +$115K +6,920 +77%
WG
97
Winton Group
United Kingdom
$292K +$260K +15,670 New
JG
98
Jain Global
New York
$286K -$915K -55,249 -78%
FRM
99
Fox Run Management
Connecticut
$280K -$918K -55,444 -77%
Citigroup
100
Citigroup
New York
$255K +$212K +12,781 +1,405%

MLTX Hedge Fund Activity: Q1 2026 in Review

147 of the 8,126 institutional investors tracked by Wall St. Rank reported a position in MoonLake Immunotherapeutics (MLTX) for Q1 2026, worth a combined $1.17B — up 58% from $743M a quarter earlier.

Buyers outnumbered sellers: 40 funds opened new MLTX positions and 21 closed out — a net gain of 19 holders — while 49 added to existing stakes and 43 trimmed.

The largest buyer was MPM BioImpact, opening a new position worth an estimated $30M. The largest seller was BVF Inc, cutting an estimated $62.1M.

  • 147 institutional investors held MoonLake Immunotherapeutics (MLTX) as of Q1 2026, up from 130 in Q4 2025.
  • Funds reported $1.17B of MoonLake Immunotherapeutics stock for Q1 2026, up 58% quarter-over-quarter.
  • 40 funds opened new MoonLake Immunotherapeutics positions in Q1 2026 and 21 closed out, a net change of +19 holders.
  • The largest MoonLake Immunotherapeutics buyer in Q1 2026 was MPM BioImpact, an estimated $30M added.
  • The largest MoonLake Immunotherapeutics seller in Q1 2026 was BVF Inc, an estimated $62.1M sold.

Based on aggregated 13F filings for Q1 2026.