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MoonLake Immunotherapeutics

134 hedge funds and large institutions have $270M invested in MoonLake Immunotherapeutics in 2025 Q3 according to their latest regulatory filings, with 49 funds opening new positions, 33 increasing their positions, 41 reducing their positions, and 45 closing their positions.

New
Increased
Maintained
Reduced
Closed

130% more call options, than puts

Call options by funds: $33.1M | Put options by funds: $14.4M

3% more funds holding

Funds holding: 130134 (+4)

9% more first-time investments, than exits

New positions opened: 49 | Existing positions closed: 45

20% less repeat investments, than reductions

Existing positions increased: 33 | Existing positions reduced: 41

33.32% less ownership

Funds ownership: 92.59%59.27% (-33%)

83% less funds holding in top 10

Funds holding in top 10: 61 (-5)

90% less capital invested

Capital invested by funds: $2.77B → $270M (-$2.5B)

Holders
134
Holders Change
+4
Holders Change %
+3.08%
% of All Funds
1.76%
Holding in Top 10
1
Holding in Top 10 Change
-5
Holding in Top 10 Change %
-83.33%
% of All Funds
0.01%
New
49
Increased
33
Reduced
41
Closed
45
Calls
$33.1M
Puts
$14.4M
Net Calls
+$18.7M
Net Calls Change
+$16.8M
Name Holding Trade Value Shares
Change
Change in
Stake
Citadel Advisors
51
Citadel Advisors
Florida
$354K -$84.7M -1,624,707 -97%
Royal Bank of Canada
52
Royal Bank of Canada
Ontario, Canada
$346K +$1.38M +26,441 +121%
Northern Trust
53
Northern Trust
Illinois
$323K +$1.6M +30,701 +214%
PCM
54
Prelude Capital Management
New York
$321K +$2.33M +44,779 New
TC
55
TwinBeech Capital
New York
$314K +$2.28M +43,735 New
Swiss National Bank
56
Swiss National Bank
Switzerland
$308K +$36.5K +700 +2%
VCM
57
Voleon Capital Management
California
$289K +$2.1M +40,273 New
Two Sigma Advisers
58
Two Sigma Advisers
New York
$282K +$2.05M +39,324 New
TSS
59
Two Sigma Securities
New York
$261K +$1.9M +36,405 New
BG
60
Bellevue Group
Switzerland
$251K +$1.67M +32,052 +1,068%
CSS
61
Cubist Systematic Strategies
Connecticut
$243K -$225K -4,326 -11%
Franklin Resources
62
Franklin Resources
California
$241K +$1.75M +33,577 New
XT
63
XTX Topco
Cayman Islands
$231K +$1.68M +32,245 New
HT
64
HAP Trading
New York
$223K +$1.62M +31,073 New
AA
65
ALPS Advisors
Colorado
$221K -$184K -3,534 -10%
Squarepoint
66
Squarepoint
New York
$220K +$684K +13,119 +75%
SCM
67
Silverarc Capital Management
Massachusetts
$215K -$2.71M -52,023 -63%
RSCM
68
Rock Springs Capital Management
Maryland
$202K +$1.47M +28,200 New
AI
69
Axiom Investors
Connecticut
$181K +$1.31M +25,180 New
JFG
70
Jefferies Financial Group
New York
$179K +$1.03M +19,811 +382%
Jane Street
71
Jane Street
New York
$158K +$1.15M +21,978 New
Legal & General Group
72
Legal & General Group
United Kingdom
$150K
Hudson Bay Capital Management
73
Hudson Bay Capital Management
Connecticut
$143K -$4.43M -85,000 -81%
HS
74
HighVista Strategies
Massachusetts
$137K -$98.7K -1,894 -9%
California State Teachers Retirement System (CalSTRS)
75
California State Teachers Retirement System (CalSTRS)
California
$136K

MLTX Hedge Fund Activity: Q3 2025 in Review

134 of the 7,620 institutional investors tracked by Wall St. Rank reported a position in MoonLake Immunotherapeutics (MLTX) for Q3 2025, worth a combined $270M — down 90% from $2.77B a quarter earlier.

Buyers outnumbered sellers: 49 funds opened new MLTX positions and 45 closed out — a net gain of 4 holders — while 33 added to existing stakes and 41 trimmed.

The largest buyer was Adage Capital Partners, opening a new position worth an estimated $78.2M. The largest seller was Cormorant Asset Management, cutting an estimated $339M.

  • 134 institutional investors held MoonLake Immunotherapeutics (MLTX) as of Q3 2025, up from 130 in Q2 2025.
  • Funds reported $270M of MoonLake Immunotherapeutics stock for Q3 2025, down 90% quarter-over-quarter.
  • 49 funds opened new MoonLake Immunotherapeutics positions in Q3 2025 and 45 closed out, a net change of +4 holders.
  • The largest MoonLake Immunotherapeutics buyer in Q3 2025 was Adage Capital Partners, an estimated $78.2M added.
  • The largest MoonLake Immunotherapeutics seller in Q3 2025 was Cormorant Asset Management, an estimated $339M sold.

Based on aggregated 13F filings for Q3 2025.