Mirum Pharmaceuticals
MIRM
214 hedge funds and large institutions have $2.44B invested in Mirum Pharmaceuticals in 2025 Q1 according to their latest regulatory filings, with 34 funds opening new positions, 85 increasing their positions, 67 reducing their positions, and 24 closing their positions.
42% more first-time investments, than exits
New positions opened: 34 | Existing positions closed: 24
27% more repeat investments, than reductions
Existing positions increased: 85 | Existing positions reduced: 67
12% more capital invested
Capital invested by funds: $2.19B → $2.44B (+$253M)
4% more funds holding
Funds holding: 205 → 214 (+9)
0.11% more ownership
Funds ownership: 110.36% → 110.47% (+0.11%)
0% more funds holding in top 10
Funds holding in top 10: 11 → 11 (0)
49% less call options, than puts
Call options by funds: $2.43M | Put options by funds: $4.78M
Top Buyers
| Rank | Fund | Capital Flow |
|---|---|---|
| 1 |
PCH
Polar Capital Holdings
London,
United Kingdom
|
+$23.6M |
| 2 |
D.E. Shaw & Co
New York
|
+$18.2M |
| 3 |
Macquarie Group
Sydney, NSW 2000,
Australia
|
+$17.3M |
| 4 |
Federated Hermes
Pittsburgh,
Pennsylvania
|
+$16.2M |
| 5 |
BNP Paribas Financial Markets
Paris,
France
|
+$11.2M |
Top Sellers
| Rank | Fund | Capital Flow |
|---|---|---|
| 1 |
APM
Avidity Partners Management
Dallas,
Texas
|
-$29.5M |
| 2 |
RSCM
Rock Springs Capital Management
Baltimore,
Maryland
|
-$24.5M |
| 3 |
MB
MPM BioImpact
Boston,
Massachusetts
|
-$24.4M |
| 4 |
Barclays
London,
United Kingdom
|
-$8.04M |
| 5 |
BBA
Baker Bros. Advisors
New York
|
-$7.88M |
MIRM Hedge Fund Activity: Q1 2025 in Review
214 of the 7,457 institutional investors tracked by Wall St. Rank reported a position in Mirum Pharmaceuticals (MIRM) for Q1 2025, worth a combined $2.44B — up 12% from $2.19B a quarter earlier.
Buyers outnumbered sellers: 34 funds opened new MIRM positions and 24 closed out — a net gain of 10 holders — while 85 added to existing stakes and 67 trimmed.
The largest buyer was Polar Capital Holdings, adding an estimated $23.6M. The largest seller was Avidity Partners Management, cutting an estimated $29.5M.
- 214 institutional investors held Mirum Pharmaceuticals (MIRM) as of Q1 2025, up from 205 in Q4 2024.
- Funds reported $2.44B of Mirum Pharmaceuticals stock for Q1 2025, up 12% quarter-over-quarter.
- 34 funds opened new Mirum Pharmaceuticals positions in Q1 2025 and 24 closed out, a net change of +10 holders.
- The largest Mirum Pharmaceuticals buyer in Q1 2025 was Polar Capital Holdings, an estimated $23.6M added.
- The largest Mirum Pharmaceuticals seller in Q1 2025 was Avidity Partners Management, an estimated $29.5M sold.
Based on aggregated 13F filings for Q1 2025.