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Mirum Pharmaceuticals
MIRM

311 hedge funds and large institutions have $6.29B invested in Mirum Pharmaceuticals in 2026 Q1 according to their latest regulatory filings, with 69 funds opening new positions, 114 increasing their positions, 88 reducing their positions, and 34 closing their positions.

New
Increased
Maintained
Reduced
Closed

1,208% more call options, than puts

Call options by funds: $19.9M | Put options by funds: $1.52M

103% more first-time investments, than exits

New positions opened: 69 | Existing positions closed: 34

45% more funds holding in top 10

Funds holding in top 10: 11 → 16 (+5)

31% more capital invested

Capital invested by funds: $4.82B → $6.29B (+$1.47B)

30% more repeat investments, than reductions

Existing positions increased: 114 | Existing positions reduced: 88

11% more funds holding

Funds holding: 281 → 311 (+30)

5.62% less ownership

Funds ownership: 118.72% → 113.1% (-5.6%)

Holders
311
Holders Change
+30
Holders Change %
+10.68%
% of All Funds
3.83%
Holding in Top 10
16
Holding in Top 10 Change
+5
Holding in Top 10 Change %
+45.45%
% of All Funds
0.2%
New
69
Increased
114
Reduced
88
Closed
34
Calls
$19.9M
Puts
$1.52M
Net Calls
+$18.4M
Net Calls Change
+$15.9M

Top Buyers

1
Fidelity Investments
Fidelity Investments
Massachusetts
+$124M
2
TCM
TCG Crossover Management
California
+$94.1M
3
FLSM
Frazier Life Sciences Management
California
+$83.2M
4
Janus Henderson Group
Janus Henderson Group
United Kingdom
+$82.8M
5
Capital World Investors
Capital World Investors
California
+$68.1M

Top Sellers

1
D.E. Shaw & Co
D.E. Shaw & Co
New York
-$73.4M
2
EAM
Eventide Asset Management
Massachusetts
-$64.4M
3
PCH
Polar Capital Holdings
United Kingdom
-$48M
4
Arrowstreet Capital
Arrowstreet Capital
Massachusetts
-$28.7M
5
PA
Perceptive Advisors
New York
-$20.5M
Name Holding Trade Value Shares
Change 		Change in
Stake
Lord, Abbett & Co
26
Lord, Abbett & Co
New Jersey
$57M +$3.49M +37,081 +6%
Bank of New York Mellon
27
Bank of New York Mellon
New York
$54M +$1.78M +18,944 +3%
Renaissance Technologies
28
Renaissance Technologies
New York
$53.8M +$13.5M +143,000 +33%
WP
29
Woodline Partners
California
$52.5M – – –
Balyasny Asset Management
30
Balyasny Asset Management
Illinois
$49.8M +$23.8M +253,161 +89%
Morgan Stanley
31
Morgan Stanley
New York
$48.5M +$9.3M +98,881 +23%
Federated Hermes
32
Federated Hermes
Pennsylvania
$46.8M +$2.28M +24,250 +5%
UBS Group
33
UBS Group
Switzerland
$45.7M +$16.4M +174,211 +54%
Connor, Clark & Lunn Investment Management (CC&L)
34
Connor, Clark & Lunn Investment Management (CC&L)
British Columbia, Canada
$44.3M -$3.97M -42,176 -8%
Loomis, Sayles & Company
35
Loomis, Sayles & Company
Massachusetts
$43.9M -$3.73M -39,657 -8%
N
36
Nuveen
North Carolina
$43.8M -$2.71M -28,818 -6%
CS
37
Candriam SCA
Luxembourg
$42.9M -$9.91M -105,374 -18%
BBA
38
Baker Bros. Advisors
New York
$41.2M +$42M +445,975 New
Charles Schwab
39
Charles Schwab
California
$39.5M +$1.67M +17,804 +4%
Pictet Asset Management
40
Pictet Asset Management
Switzerland
$39.1M -$14.5M -153,763 -27%
BCM
41
Boone Capital Management
Georgia
$38.9M – – –
NAMI
42
Nomura Asset Management International
Pennsylvania
$37.4M -$1.55M -16,524 -4%
FTM
43
First Turn Management
California
$37M -$7.63M -81,100 -17%
SCM
44
Soleus Capital Management
Connecticut
$37M -$16.3M -173,308 -30%
EA
45
Emerald Advisers
Pennsylvania
$36.7M +$2.83M +30,129 +8%
Northern Trust
46
Northern Trust
Illinois
$36.5M +$1.89M +20,056 +5%
NCGI
47
Next Century Growth Investors
Minnesota
$35.6M +$1.65M +17,504 +5%
TCM
48
TimesSquare Capital Management
New York
$34.8M -$1.82M -19,354 -5%
Adage Capital Partners
49
Adage Capital Partners
Massachusetts
$34.6M -$8.7M -92,468 -20%
Millennium Management
50
Millennium Management
New York
$34M +$11.7M +124,302 +51%
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MIRM Hedge Fund Activity: Q1 2026 in Review

311 of the 8,126 institutional investors tracked by Wall St. Rank reported a position in Mirum Pharmaceuticals (MIRM) for Q1 2026, worth a combined $6.29B — up 31% from $4.82B a quarter earlier.

Buyers outnumbered sellers: 69 funds opened new MIRM positions and 34 closed out — a net gain of 35 holders — while 114 added to existing stakes and 88 trimmed.

The largest buyer was Fidelity Investments, adding an estimated $124M. The largest seller was D.E. Shaw & Co, cutting an estimated $73.4M.

  • 311 institutional investors held Mirum Pharmaceuticals (MIRM) as of Q1 2026, up from 281 in Q4 2025.
  • Funds reported $6.29B of Mirum Pharmaceuticals stock for Q1 2026, up 31% quarter-over-quarter.
  • 69 funds opened new Mirum Pharmaceuticals positions in Q1 2026 and 34 closed out, a net change of +35 holders.
  • The largest Mirum Pharmaceuticals buyer in Q1 2026 was Fidelity Investments, an estimated $124M added.
  • The largest Mirum Pharmaceuticals seller in Q1 2026 was D.E. Shaw & Co, an estimated $73.4M sold.

Based on aggregated 13F filings for Q1 2026.