MeiraGTx Holdings
MGTX
130 hedge funds and large institutions have $518M invested in MeiraGTx Holdings in 2025 Q4 according to their latest regulatory filings, with 20 funds opening new positions, 44 increasing their positions, 34 reducing their positions, and 12 closing their positions.
113% more call options, than puts
Call options by funds: $495K | Put options by funds: $232K
67% more first-time investments, than exits
New positions opened: 20 | Existing positions closed: 12
29% more repeat investments, than reductions
Existing positions increased: 44 | Existing positions reduced: 34
6% more funds holding
Funds holding: 123 → 130 (+7)
1.28% more ownership
Funds ownership: 79.7% → 80.98% (+1.3%)
2% less capital invested
Capital invested by funds: $528M → $518M (-$9.37M)
20% less funds holding in top 10
Funds holding in top 10: 5 → 4 (-1)
Top Buyers
| Rank | Fund | Capital Flow |
|---|---|---|
| 1 |
RCMNY
Rubric Capital Management (New York)
New York
|
+$20.4M |
| 2 |
Millennium Management
New York
|
+$5.12M |
| 3 |
Morgan Stanley
New York
|
+$4.88M |
| 4 |
OM
Opaleye Management
Boston,
Massachusetts
|
+$3.25M |
| 5 |
JFG
Jefferies Financial Group
New York
|
+$2.48M |
Top Sellers
| Rank | Fund | Capital Flow |
|---|---|---|
| 1 |
PA
Perceptive Advisors
New York
|
-$19.1M |
| 2 |
JGC
J. Goldman & Co
New York
|
-$12.3M |
| 3 |
PM
Prosight Management
Dallas,
Texas
|
-$7.31M |
| 4 |
Royal Bank of Canada
Toronto,
Ontario, Canada
|
-$2.41M |
| 5 |
Adage Capital Partners
Boston,
Massachusetts
|
-$1.53M |
MGTX Hedge Fund Activity: Q4 2025 in Review
130 of the 8,223 institutional investors tracked by Wall St. Rank reported a position in MeiraGTx Holdings (MGTX) for Q4 2025, worth a combined $518M — down 1.8% from $528M a quarter earlier.
Buyers outnumbered sellers: 20 funds opened new MGTX positions and 12 closed out — a net gain of 8 holders — while 44 added to existing stakes and 34 trimmed.
The largest buyer was Rubric Capital Management (New York), adding an estimated $20.4M. The largest seller was Perceptive Advisors, cutting an estimated $19.1M.
- 130 institutional investors held MeiraGTx Holdings (MGTX) as of Q4 2025, up from 123 in Q3 2025.
- Funds reported $518M of MeiraGTx Holdings stock for Q4 2025, down 1.8% quarter-over-quarter.
- 20 funds opened new MeiraGTx Holdings positions in Q4 2025 and 12 closed out, a net change of +8 holders.
- The largest MeiraGTx Holdings buyer in Q4 2025 was Rubric Capital Management (New York), an estimated $20.4M added.
- The largest MeiraGTx Holdings seller in Q4 2025 was Perceptive Advisors, an estimated $19.1M sold.
Based on aggregated 13F filings for Q4 2025.