MeiraGTx Holdings
MGTX
133 hedge funds and large institutions have $583M invested in MeiraGTx Holdings in 2026 Q1 according to their latest regulatory filings, with 20 funds opening new positions, 49 increasing their positions, 39 reducing their positions, and 14 closing their positions.
43% more first-time investments, than exits
New positions opened: 20 | Existing positions closed: 14
26% more repeat investments, than reductions
Existing positions increased: 49 | Existing positions reduced: 39
13% more capital invested
Capital invested by funds: $518M → $583M (+$64.8M)
2.74% more ownership
Funds ownership: 80.98% → 83.72% (+2.7%)
2% more funds holding
Funds holding: 130 → 133 (+3)
25% less funds holding in top 10
Funds holding in top 10: 4 → 3 (-1)
40% less call options, than puts
Call options by funds: $251K | Put options by funds: $417K
Top Buyers
| Rank | Fund | Capital Flow |
|---|---|---|
| 1 |
OM
Opaleye Management
Boston,
Massachusetts
|
+$13.2M |
| 2 |
RCMNY
Rubric Capital Management (New York)
New York
|
+$6.26M |
| 3 |
KCM
Kennedy Capital Management
St Louis,
Missouri
|
+$5.98M |
| 4 |
LGM
Logos Global Management
San Francisco,
California
|
+$5.32M |
| 5 |
Millennium Management
New York
|
+$2.2M |
Top Sellers
| Rank | Fund | Capital Flow |
|---|---|---|
| 1 |
2L
22NW LP
Seattle,
Washington
|
-$4.66M |
| 2 |
PM
Prosight Management
Dallas,
Texas
|
-$4.4M |
| 3 |
SC
Stempoint Capital
New York
|
-$2.29M |
| 4 |
Morgan Stanley
New York
|
-$1.82M |
| 5 |
RA
Royce & Associates
New York
|
-$1.4M |
MGTX Hedge Fund Activity: Q1 2026 in Review
133 of the 8,126 institutional investors tracked by Wall St. Rank reported a position in MeiraGTx Holdings (MGTX) for Q1 2026, worth a combined $583M — up 13% from $518M a quarter earlier.
Buyers outnumbered sellers: 20 funds opened new MGTX positions and 14 closed out — a net gain of 6 holders — while 49 added to existing stakes and 39 trimmed.
The largest buyer was Opaleye Management, adding an estimated $13.2M. The largest seller was 22NW LP, exiting entirely with an estimated $4.66M sold.
- 133 institutional investors held MeiraGTx Holdings (MGTX) as of Q1 2026, up from 130 in Q4 2025.
- Funds reported $583M of MeiraGTx Holdings stock for Q1 2026, up 13% quarter-over-quarter.
- 20 funds opened new MeiraGTx Holdings positions in Q1 2026 and 14 closed out, a net change of +6 holders.
- The largest MeiraGTx Holdings buyer in Q1 2026 was Opaleye Management, an estimated $13.2M added.
- The largest MeiraGTx Holdings seller in Q1 2026 was 22NW LP, an estimated $4.66M sold.
Based on aggregated 13F filings for Q1 2026.