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MacroGenics
MGNX

109 hedge funds and large institutions have $125M invested in MacroGenics in 2026 Q1 according to their latest regulatory filings, with 32 funds opening new positions, 29 increasing their positions, 28 reducing their positions, and 9 closing their positions.

New
Increased
Maintained
Reduced
Closed

1,264% more call options, than puts

Call options by funds: $600K | Put options by funds: $44K

256% more first-time investments, than exits

New positions opened: 32 | Existing positions closed: 9

94% more capital invested

Capital invested by funds: $64.2M → $125M (+$60.6M)

24% more funds holding

Funds holding: 88 → 109 (+21)

4.87% more ownership

Funds ownership: 63.05% → 67.92% (+4.9%)

4% more repeat investments, than reductions

Existing positions increased: 29 | Existing positions reduced: 28

Holders
109
Holders Change
+21
Holders Change %
+23.86%
% of All Funds
1.34%
Holding in Top 10
–
Holding in Top 10 Change
–
Holding in Top 10 Change %
–
% of All Funds
–
New
32
Increased
29
Reduced
28
Closed
9
Calls
$600K
Puts
$44K
Net Calls
+$556K
Net Calls Change
+$432K

Top Buyers

1
RCM
RA Capital Management
Massachusetts
+$3.98M
2
Two Sigma Investments
Two Sigma Investments
New York
+$3.26M
3
Millennium Management
Millennium Management
New York
+$1.75M
4
Marshall Wace
Marshall Wace
United Kingdom
+$1.58M
5
DP
Diadema Partners
New Jersey
+$1.28M

Top Sellers

1
JFG
Jefferies Financial Group
New York
-$2.96M
2
Jane Street
Jane Street
New York
-$1.38M
3
Jacobs Levy Equity Management
Jacobs Levy Equity Management
New Jersey
-$981K
4
AC
Armistice Capital
New York
-$665K
5
Universal-Beteiligungs- und Servicegesellschaft
Universal-Beteiligungs- und Servicegesellschaft
Germany
-$619K
Name Holding Trade Value Shares
Change 		Change in
Stake
AC
1
Armistice Capital
New York
$17.4M -$665K -312,000 -5%
Renaissance Technologies
2
Renaissance Technologies
New York
$8.56M +$117K +54,928 +2%
Millennium Management
3
Millennium Management
New York
$8.08M +$1.75M +819,877 +42%
VCM
4
Vanguard Capital Management
Pennsylvania
$7.67M +$5.66M +2,653,853 New
Acadian Asset Management
5
Acadian Asset Management
Massachusetts
$7.35M +$54.6K +25,590 +1%
Two Sigma Investments
6
Two Sigma Investments
New York
$7.31M +$3.26M +1,528,355 +153%
Bank of America
7
Bank of America
North Carolina
$6.94M +$1.2M +564,094 +31%
Marshall Wace
8
Marshall Wace
United Kingdom
$5.85M +$1.58M +740,963 +58%
RCM
9
RA Capital Management
Massachusetts
$5.39M +$3.98M +1,864,176 New
WA
10
Wasatch Advisors
Utah
$4.51M -$483K -226,655 -13%
VPM
11
Vanguard Portfolio Management
Pennsylvania
$3.49M +$2.58M +1,208,775 New
BlackRock
12
BlackRock
New York
$3.36M +$22.4K +10,497 +0.9%
D.E. Shaw & Co
13
D.E. Shaw & Co
New York
$3.06M +$644K +301,777 +40%
Connor, Clark & Lunn Investment Management (CC&L)
14
Connor, Clark & Lunn Investment Management (CC&L)
British Columbia, Canada
$2.51M +$103K +48,429 +6%
Citadel Advisors
15
Citadel Advisors
Florida
$2.26M -$539K -252,535 -24%
Geode Capital Management
16
Geode Capital Management
Massachusetts
$2.02M +$89.6K +42,021 +6%
Jane Street
17
Jane Street
New York
$1.76M -$1.38M -646,414 -52%
DP
18
Diadema Partners
New Jersey
$1.73M +$1.28M +600,000 New
Mackenzie Financial
19
Mackenzie Financial
Ontario, Canada
$1.73M +$831K +389,563 +187%
AAA
20
Affinity Asset Advisors
New York
$1.45M +$33.5K +15,692 +3%
Susquehanna International Group
21
Susquehanna International Group
Pennsylvania
$1.31M +$818K +383,686 +560%
Jacobs Levy Equity Management
22
Jacobs Levy Equity Management
New Jersey
$1.27M -$981K -459,914 -51%
NAMI
23
Nomura Asset Management International
Pennsylvania
$1.21M – – –
GCP
24
GSA Capital Partners
United Kingdom
$1.1M -$280K -131,357 -26%
VFT
25
Vanguard Fiduciary Trust
Pennsylvania
$983K +$725K +340,089 New
1
2 3 4 5

MGNX Hedge Fund Activity: Q1 2026 in Review

109 of the 8,126 institutional investors tracked by Wall St. Rank reported a position in MacroGenics (MGNX) for Q1 2026, worth a combined $125M — up 94% from $64.2M a quarter earlier.

Buyers outnumbered sellers: 32 funds opened new MGNX positions and 9 closed out — a net gain of 23 holders — while 29 added to existing stakes and 28 trimmed.

The largest buyer was RA Capital Management, opening a new position worth an estimated $3.98M. The largest seller was Jefferies Financial Group, exiting entirely with an estimated $2.96M sold.

  • 109 institutional investors held MacroGenics (MGNX) as of Q1 2026, up from 88 in Q4 2025.
  • Funds reported $125M of MacroGenics stock for Q1 2026, up 94% quarter-over-quarter.
  • 32 funds opened new MacroGenics positions in Q1 2026 and 9 closed out, a net change of +23 holders.
  • The largest MacroGenics buyer in Q1 2026 was RA Capital Management, an estimated $3.98M added.
  • The largest MacroGenics seller in Q1 2026 was Jefferies Financial Group, an estimated $2.96M sold.

Based on aggregated 13F filings for Q1 2026.