MacroGenics
MGNX
About: Macrogenics Inc is a biotechnology company focused on discovering and developing antibody-based therapeutics for the treatment of cancer. Its product includes MARGENZA, which is for the treatment of adult patients with metastatic HER2-positive breast cancer. It's a pipeline of product candidates designed to target either various tumor-associated antigens or immune checkpoint molecules. The company has three proprietary product candidates in clinical development: lorigerlimab, a bispecific DART molecule that targets checkpoint inhibitors PD-1 and CTLA-4; MGC026, an ADC that targets B7-H3 and delivers a novel topoisomerase I inhibitor (TOP1i)-based linker-payload, and MGC028, an ADC that targets ADAM9 and delivers a novel TOP1i-based linker-payload.
Employees: 341
Fund manager confidence
Based on 2025 Q2 regulatory disclosures by fund managers ($100M+ AUM)
66% more call options, than puts
Call options by funds: $83K | Put options by funds: $50K
8.77% less ownership
Funds ownership: 85.26% [Q1] → 76.49% (-8.77%) [Q2]
12% less funds holding
Funds holding: 127 [Q1] → 112 (-15) [Q2]
14% less capital invested
Capital invested by funds: $68.3M [Q1] → $58.4M (-$9.84M) [Q2]
24% less repeat investments, than reductions
Existing positions increased: 26 | Existing positions reduced: 34
37% less first-time investments, than exits
New positions opened: 26 | Existing positions closed: 41
Research analyst outlook
1 Wall Street Analyst provided 1 year price targets over the past 3 months
1 analyst rating
Leerink Partners
|
$5
|
Outperform
Maintained
|
15 Aug 2025 |
Financial journalist opinion