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MacroGenics
MGNX

112 hedge funds and large institutions have $58.5M invested in MacroGenics in 2025 Q2 according to their latest regulatory filings, with 26 funds opening new positions, 26 increasing their positions, 35 reducing their positions, and 42 closing their positions.

New
Increased
Maintained
Reduced
Closed

66% more call options, than puts

Call options by funds: $83K | Put options by funds: $50K

8.72% less ownership

Funds ownership: 85.32% → 76.6% (-8.7%)

13% less funds holding

Funds holding: 128 → 112 (-16)

14% less capital invested

Capital invested by funds: $68.3M → $58.5M (-$9.82M)

26% less repeat investments, than reductions

Existing positions increased: 26 | Existing positions reduced: 35

38% less first-time investments, than exits

New positions opened: 26 | Existing positions closed: 42

Holders
112
Holders Change
-16
Holders Change %
-12.5%
% of All Funds
1.47%
Holding in Top 10
–
Holding in Top 10 Change
–
Holding in Top 10 Change %
–
% of All Funds
–
New
26
Increased
26
Reduced
35
Closed
42
Calls
$83K
Puts
$50K
Net Calls
+$33K
Net Calls Change
+$149K

Top Buyers

Rank Fund Capital Flow
1
EC
EcoR1 Capital
California
+$2.32M
2
Jane Street
Jane Street
New York
+$742K
3
Goldman Sachs
Goldman Sachs
New York
+$726K
4
CSS
Cubist Systematic Strategies
Connecticut
+$511K
5
Jacobs Levy Equity Management
Jacobs Levy Equity Management
New Jersey
+$492K

Top Sellers

Rank Fund Capital Flow
1
BlackRock
BlackRock
New York
-$4.49M
2
State Street
State Street
Massachusetts
-$1.61M
3
RSCM
Rock Springs Capital Management
Maryland
-$1.45M
4
Geode Capital Management
Geode Capital Management
Massachusetts
-$1.12M
5
GCP
GSA Capital Partners
United Kingdom
-$570K
Name Holding Trade Value Shares
Change 		Change in
Stake
HWM
101
HighMark Wealth Management
Minnesota
$484 – – –
Northwestern Mutual Wealth Management
102
Northwestern Mutual Wealth Management
Wisconsin
$439 +$527 +363 New
LWCFA
103
Loring Wolcott & Coolidge Fiduciary Advisors
Massachusetts
$258 – – –
PD
104
Point72 (DIFC)
United Arab Emirates
$230 +$276 +190 New
FMII
105
Farmers & Merchants Investments Inc
Nebraska
$97 – – –
EWA
106
EverSource Wealth Advisors
Alabama
$57 -$26 -18 -28%
Comerica Bank
107
Comerica Bank
Texas
$53 – – –
Jones Financial Companies
108
Jones Financial Companies
Missouri
$36 – – –
TWD
109
True Wealth Design
Ohio
$15 -$7 -5 -29%
RSCM
110
Rock Springs Capital Management
Maryland
– -$1.45M -1,145,214 Closed
GCP
111
GSA Capital Partners
United Kingdom
– -$570K -448,530 Closed
SO
112
STRS Ohio
Ohio
– -$263K -207,200 Closed
N
113
Nuveen
North Carolina
– -$252K -198,470 Closed
Bank of New York Mellon
114
Bank of New York Mellon
New York
– -$199K -156,787 Closed
SFI
115
Susquehanna Fundamental Investments
Pennsylvania
– -$141K -111,280 Closed
Verition Fund Management
116
Verition Fund Management
Connecticut
– -$137K -108,058 Closed
AllianceBernstein
117
AllianceBernstein
Tennessee
– -$130K -102,730 Closed
VOYA Investment Management
118
VOYA Investment Management
Georgia
– -$124K -97,922 Closed
RhumbLine Advisers
119
RhumbLine Advisers
Massachusetts
– -$111K -87,215 Closed
IIM
120
INTECH Investment Management
Florida
– -$80.1K -63,102 Closed
ETC
121
Exchange Traded Concepts
Oklahoma
– -$74.2K -58,434 Closed
Deutsche Bank
122
Deutsche Bank
Germany
– -$64.9K -51,093 Closed
AA
123
ALPS Advisors
Colorado
– -$61.8K -48,646 Closed
American Century Companies
124
American Century Companies
Missouri
– -$50.2K -39,525 Closed
Mirae Asset Global ETFs Holdings
125
Mirae Asset Global ETFs Holdings
Hong Kong
– -$46.4K -36,539 Closed
3 4
5
6 7

MGNX Hedge Fund Activity: Q2 2025 in Review

112 of the 7,596 institutional investors tracked by Wall St. Rank reported a position in MacroGenics (MGNX) for Q2 2025, worth a combined $58.5M — down 14% from $68.3M a quarter earlier.

Sellers outnumbered buyers: 42 funds closed out of MGNX and 26 opened new positions — a net loss of 16 holders — while 35 trimmed existing stakes and 26 added.

The largest buyer was EcoR1 Capital, opening a new position worth an estimated $2.32M. The largest seller was BlackRock, cutting an estimated $4.49M.

  • 112 institutional investors held MacroGenics (MGNX) as of Q2 2025, down from 128 in Q1 2025.
  • Funds reported $58.5M of MacroGenics stock for Q2 2025, down 14% quarter-over-quarter.
  • 26 funds opened new MacroGenics positions in Q2 2025 and 42 closed out, a net change of -16 holders.
  • The largest MacroGenics buyer in Q2 2025 was EcoR1 Capital, an estimated $2.32M added.
  • The largest MacroGenics seller in Q2 2025 was BlackRock, an estimated $4.49M sold.

Based on aggregated 13F filings for Q2 2025.