MacroGenics
MGNX
88 hedge funds and large institutions have $64.2M invested in MacroGenics in 2025 Q4 according to their latest regulatory filings, with 12 funds opening new positions, 30 increasing their positions, 26 reducing their positions, and 24 closing their positions.
517% more call options, than puts
Call options by funds: $148K | Put options by funds: $24K
15% more repeat investments, than reductions
Existing positions increased: 30 | Existing positions reduced: 26
9.84% less ownership
Funds ownership: 72.89% → 63.05% (-9.8%)
15% less funds holding
Funds holding: 104 → 88 (-16)
17% less capital invested
Capital invested by funds: $77.4M → $64.2M (-$13.2M)
50% less first-time investments, than exits
New positions opened: 12 | Existing positions closed: 24
Top Buyers
| Rank | Fund | Capital Flow |
|---|---|---|
| 1 |
JFG
Jefferies Financial Group
New York
|
+$2.89M |
| 2 |
Bank of America
Charlotte,
North Carolina
|
+$2.56M |
| 3 |
Renaissance Technologies
New York
|
+$1.9M |
| 4 |
Marshall Wace
London,
United Kingdom
|
+$1.03M |
| 5 |
Two Sigma Investments
New York
|
+$884K |
Top Sellers
| Rank | Fund | Capital Flow |
|---|---|---|
| 1 |
BG
Bellevue Group
Kuesnacht,
Switzerland
|
-$16.7M |
| 2 |
FLSM
Frazier Life Sciences Management
Palo Alto,
California
|
-$5.34M |
| 3 |
Morgan Stanley
New York
|
-$1.3M |
| 4 |
JP Morgan Chase
New York
|
-$1.18M |
| 5 |
Macquarie Group
Sydney, NSW 2000,
Australia
|
-$706K |
MGNX Hedge Fund Activity: Q4 2025 in Review
88 of the 8,223 institutional investors tracked by Wall St. Rank reported a position in MacroGenics (MGNX) for Q4 2025, worth a combined $64.2M — down 17% from $77.4M a quarter earlier.
Sellers outnumbered buyers: 24 funds closed out of MGNX and 12 opened new positions — a net loss of 12 holders — while 26 trimmed existing stakes and 30 added.
The largest buyer was Jefferies Financial Group, opening a new position worth an estimated $2.89M. The largest seller was Bellevue Group, exiting entirely with an estimated $16.7M sold.
- 88 institutional investors held MacroGenics (MGNX) as of Q4 2025, down from 104 in Q3 2025.
- Funds reported $64.2M of MacroGenics stock for Q4 2025, down 17% quarter-over-quarter.
- 12 funds opened new MacroGenics positions in Q4 2025 and 24 closed out, a net change of -12 holders.
- The largest MacroGenics buyer in Q4 2025 was Jefferies Financial Group, an estimated $2.89M added.
- The largest MacroGenics seller in Q4 2025 was Bellevue Group, an estimated $16.7M sold.
Based on aggregated 13F filings for Q4 2025.