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MacroGenics
MGNX

104 hedge funds and large institutions have $77.4M invested in MacroGenics in 2025 Q3 according to their latest regulatory filings, with 17 funds opening new positions, 30 increasing their positions, 26 reducing their positions, and 24 closing their positions.

New
Increased
Maintained
Reduced
Closed

32% more capital invested

Capital invested by funds: $58.5M → $77.4M (+$18.9M)

15% more repeat investments, than reductions

Existing positions increased: 30 | Existing positions reduced: 26

3.71% less ownership

Funds ownership: 76.6% → 72.89% (-3.7%)

7% less funds holding

Funds holding: 112 → 104 (-8)

29% less first-time investments, than exits

New positions opened: 17 | Existing positions closed: 24

30% less call options, than puts

Call options by funds: $115K | Put options by funds: $165K

Holders
104
Holders Change
-8
Holders Change %
-7.14%
% of All Funds
1.36%
Holding in Top 10
–
Holding in Top 10 Change
–
Holding in Top 10 Change %
–
% of All Funds
–
New
17
Increased
30
Reduced
26
Closed
24
Calls
$115K
Puts
$165K
Net Calls
-$50K
Net Calls Change
-$83K

Top Buyers

Rank Fund Capital Flow
1
Morgan Stanley
Morgan Stanley
New York
+$879K
2
Renaissance Technologies
Renaissance Technologies
New York
+$607K
3
Squarepoint
Squarepoint
New York
+$534K
4
Citadel Advisors
Citadel Advisors
Florida
+$521K
5
VCM
Voleon Capital Management
California
+$498K

Top Sellers

Rank Fund Capital Flow
1
WA
Wasatch Advisors
Utah
-$2.11M
2
EC
EcoR1 Capital
California
-$1.94M
3
Goldman Sachs
Goldman Sachs
New York
-$712K
4
Charles Schwab
Charles Schwab
California
-$493K
5
BlackRock
BlackRock
New York
-$451K
Name Holding Trade Value Shares
Change 		Change in
Stake
State Street
26
State Street
Massachusetts
$461K -$41.6K -25,700 -9%
Goldman Sachs
27
Goldman Sachs
New York
$435K -$712K -439,626 -63%
Susquehanna International Group
28
Susquehanna International Group
Pennsylvania
$376K +$44K +27,168 +14%
D.E. Shaw & Co
29
D.E. Shaw & Co
New York
$373K +$197K +121,689 +121%
TCM
30
Tang Capital Management
California
$368K – – –
Universal-Beteiligungs- und Servicegesellschaft
31
Universal-Beteiligungs- und Servicegesellschaft
Germany
$353K +$340K +210,000 New
Bank of America
32
Bank of America
North Carolina
$352K +$63.7K +39,359 +23%
XT
33
XTX Topco
Cayman Islands
$292K +$257K +158,476 +1,024%
CF
34
Cantor Fitzgerald
New York
$269K +$259K +160,000 New
Northern Trust
35
Northern Trust
Illinois
$254K -$2.87K -1,772 -1%
CSS
36
Cubist Systematic Strategies
Connecticut
$184K -$393K -242,879 -69%
LSA
37
Leonteq Securities AG
Switzerland
$168K – – –
Ameriprise
38
Ameriprise
Minnesota
$160K -$15.3K -9,476 -9%
BCM
39
Bridgeway Capital Management
Texas
$149K -$72.8K -45,000 -34%
AG
40
Algert Global
California
$148K +$143K +88,130 New
BNP Paribas Financial Markets
41
BNP Paribas Financial Markets
France
$146K +$65.6K +40,539 +88%
Invesco
42
Invesco
Georgia
$142K +$37.9K +23,421 +38%
IC
43
Ikarian Capital
Texas
$135K – – –
Fidelity Investments
44
Fidelity Investments
Massachusetts
$106K -$940 -581 -0.9%
PAM
45
Panagora Asset Management
Massachusetts
$103K +$99.1K +61,200 New
GCP
46
GSA Capital Partners
United Kingdom
$102K +$98.4K +60,801 New
CFM
47
Catalyst Funds Management
Australia
$91.7K +$42.2K +26,100 +92%
Russell Investments Group
48
Russell Investments Group
United Kingdom
$85.8K -$743 -459 -0.9%
UBS Group
49
UBS Group
Switzerland
$80.3K +$6.71K +4,144 +9%
QC
50
Quadrature Capital
United Kingdom
$71.8K +$35K +21,609 +102%
1
2
3 4 5

MGNX Hedge Fund Activity: Q3 2025 in Review

104 of the 7,621 institutional investors tracked by Wall St. Rank reported a position in MacroGenics (MGNX) for Q3 2025, worth a combined $77.4M — up 32% from $58.5M a quarter earlier.

Sellers outnumbered buyers: 24 funds closed out of MGNX and 17 opened new positions — a net loss of 7 holders — while 26 trimmed existing stakes and 30 added.

The largest buyer was Morgan Stanley, adding an estimated $879K. The largest seller was Wasatch Advisors, cutting an estimated $2.11M.

  • 104 institutional investors held MacroGenics (MGNX) as of Q3 2025, down from 112 in Q2 2025.
  • Funds reported $77.4M of MacroGenics stock for Q3 2025, up 32% quarter-over-quarter.
  • 17 funds opened new MacroGenics positions in Q3 2025 and 24 closed out, a net change of -7 holders.
  • The largest MacroGenics buyer in Q3 2025 was Morgan Stanley, an estimated $879K added.
  • The largest MacroGenics seller in Q3 2025 was Wasatch Advisors, an estimated $2.11M sold.

Based on aggregated 13F filings for Q3 2025.