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Lyra Therapeutics
LYRA

Overview Fund Activity

57 hedge funds and large institutions have $3.23M invested in Lyra Therapeutics in 2025 Q1 according to their latest regulatory filings, with 6 funds opening new positions, 14 increasing their positions, 19 reducing their positions, and 3 closing their positions.

Holders
57
Holders Change
+3
Holders Change %
+5.56%
% of All Funds
0.77%
Holding in Top 10
–
Holding in Top 10 Change
–
Holding in Top 10 Change %
–
% of All Funds
–
New
6
Increased
14
Reduced
19
Closed
3
Calls
$7K
Puts
$4K
Net Calls
+$3K
Net Calls Change
-$1K

Top Buyers

1
Geode Capital Management
1
Geode Capital Management
Massachusetts
$128K
2
Susquehanna International Group
2
Susquehanna International Group
Pennsylvania
$27.5K
3
Northern Trust
3
Northern Trust
Illinois
$42K
4
RhumbLine Advisers
4
RhumbLine Advisers
Massachusetts
$11K
5
Jane Street
5
Jane Street
New York
$5.56K

Top Sellers

1
SB
1
Samsara BioCapital
California
$176K
2
Qube Research & Technologies (QRT)
2
Qube Research & Technologies (QRT)
United Kingdom
$0
3
Goldman Sachs
3
Goldman Sachs
New York
$46.8K
4
Morgan Stanley
4
Morgan Stanley
New York
$8.29K
5
JPMorgan Chase & Co
5
JPMorgan Chase & Co
New York
$7.11K
Name Market Value Shares Shares
Change 		Shares
Change %
Barclays
26
Barclays
United Kingdom
$6K 50,038 -25,216 -34%
Jane Street
27
Jane Street
New York
$5.56K 43,997 +43,997 New
Citigroup
28
Citigroup
New York
$4.44K 35,177 -2,925 -8%
AllianceBernstein
29
AllianceBernstein
Tennessee
$4.18K 33,120 – –
SEI Investments
30
SEI Investments
Pennsylvania
$3.83K 30,067 -54,008 -64%
Mirae Asset Global ETFs Holdings
31
Mirae Asset Global ETFs Holdings
Hong Kong
$3.67K 29,018 +1,248 +4%
Wells Fargo
32
Wells Fargo
California
$3.2K 25,305 +561 +2%
T. Rowe Price Associates
33
T. Rowe Price Associates
Maryland
$3K 17,541 – –
CF
34
Corebridge Financial
Texas
$2.99K 23,709 -352 -1%
Invesco
35
Invesco
Georgia
$2.98K 23,626 – –
Bank of America
36
Bank of America
North Carolina
$2.69K 21,352 -31,312 -59%
IIM
37
INTECH Investment Management
Florida
$2.09K 16,560 +16,560 New
SG Americas Securities
38
SG Americas Securities
New York
$2K 14,620 -17,287 -54%
Squarepoint
39
Squarepoint
New York
$1.93K 15,283 +15,283 New
AHL
40
Abel Hall LLC
Louisiana
$1.54K 12,214 -5,433 -31%
CWM
41
CIBC World Markets
New York
$1.36K 10,739 +10,739 New
ProShare Advisors
42
ProShare Advisors
Maryland
$1.32K 10,477 -3,154 -23%
SCA
43
Sassicaia Capital Advisers
New York
$1.26K 10,000 +10,000 New
Carson Wealth (CWM LLC)
44
Carson Wealth (CWM LLC)
Nebraska
$1K 6,677 +1,306 +24%
Royal Bank of Canada
45
Royal Bank of Canada
Ontario, Canada
$1K 8,019 +2,725 +51%
Northwestern Mutual Wealth Management
46
Northwestern Mutual Wealth Management
Wisconsin
$758 6,000 +6,000 New
AIP
47
Ameritas Investment Partners
Nebraska
$599 4,741 – –
SS
48
SBI Securities
Japan
$540 4,272 +3 +0.1%
California State Teachers Retirement System (CalSTRS)
49
California State Teachers Retirement System (CalSTRS)
California
$443 3,507 – –
Comerica Bank
50
Comerica Bank
Texas
$146 1,159 – –
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