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Lexeo Therapeutics

146 hedge funds and large institutions have $759M invested in Lexeo Therapeutics in 2025 Q4 according to their latest regulatory filings, with 47 funds opening new positions, 61 increasing their positions, 26 reducing their positions, and 9 closing their positions.

New
Increased
Maintained
Reduced
Closed

422% more first-time investments, than exits

New positions opened: 47 | Existing positions closed: 9

135% more repeat investments, than reductions

Existing positions increased: 61 | Existing positions reduced: 26

132% more capital invested

Capital invested by funds: $327M → $759M (+$432M)

34% more funds holding

Funds holding: 109146 (+37)

13.42% more ownership

Funds ownership: 91.34%104.76% (+13%)

0% more funds holding in top 10

Funds holding in top 10: 11 (0)

5% less call options, than puts

Call options by funds: $136K | Put options by funds: $143K

Holders
146
Holders Change
+37
Holders Change %
+33.94%
% of All Funds
1.78%
Holding in Top 10
1
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
0.01%
New
47
Increased
61
Reduced
26
Closed
9
Calls
$136K
Puts
$143K
Net Calls
-$7K
Net Calls Change
+$77K
Name Holding Trade Value Shares
Change
Change in
Stake
SL
26
Siren LLC
Connecticut
$7.16M +$1.07M +117,187 +19%
SCM
27
Silverarc Capital Management
Massachusetts
$6.13M -$1.47M -161,003 -21%
IC
28
Ikarian Capital
Texas
$5.09M -$498K -54,590 -10%
D.E. Shaw & Co
29
D.E. Shaw & Co
New York
$4.77M +$4.26M +467,387 +3,646%
Invesco
30
Invesco
Georgia
$4.6M +$4.23M +463,029 New
Northern Trust
31
Northern Trust
Illinois
$4.54M +$2.01M +220,599 +93%
Verition Fund Management
32
Verition Fund Management
Connecticut
$4.25M +$124K +13,595 +3%
Two Sigma Investments
33
Two Sigma Investments
New York
$3.98M +$2.88M +315,804 +373%
DCM
34
DAFNA Capital Management
California
$3.38M -$157K -17,224 -5%
AQR Capital Management
35
AQR Capital Management
Connecticut
$3.35M -$96.2K -10,537 -3%
UBS Group
36
UBS Group
Switzerland
$2.79M +$284K +31,174 +12%
BNP Paribas Financial Markets
37
BNP Paribas Financial Markets
France
$2.56M +$2.07M +226,690 +738%
Ameriprise
38
Ameriprise
Minnesota
$2.42M +$700K +76,756 +46%
YIH
39
Y-Intercept (HK)
Hong Kong
$2.3M +$2.11M +231,163 New
Renaissance Technologies
40
Renaissance Technologies
New York
$2.16M +$625K +68,472 +46%
N
41
Nuveen
North Carolina
$2.1M +$1.63M +178,427 +539%
PFM
42
Privium Fund Management
Netherlands
$1.91M +$1.77K +194 +0.1%
Charles Schwab
43
Charles Schwab
California
$1.91M +$789K +86,450 +82%
Barclays
44
Barclays
United Kingdom
$1.87M +$704K +77,175 +69%
SSC
45
Spruce Street Capital
New York
$1.74M +$1.6M +175,000 New
Bank of New York Mellon
46
Bank of New York Mellon
New York
$1.66M +$868K +95,072 +133%
Bank of America
47
Bank of America
North Carolina
$1.59M +$1.2M +132,009 +467%
Morgan Stanley
48
Morgan Stanley
New York
$1.39M +$384K +42,124 +43%
Jane Street
49
Jane Street
New York
$1.39M +$96.9K +10,624 +8%
PA
50
Perceptive Advisors
New York
$1.39M