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LENZ

LENZ Therapeutics

166 hedge funds and large institutions have $1.36B invested in LENZ Therapeutics in 2025 Q3 according to their latest regulatory filings, with 57 funds opening new positions, 65 increasing their positions, 22 reducing their positions, and 4 closing their positions.

New
Increased
Maintained
Reduced
Closed

1,325% more first-time investments, than exits

New positions opened: 57 | Existing positions closed: 4

195% more repeat investments, than reductions

Existing positions increased: 65 | Existing positions reduced: 22

87% more capital invested

Capital invested by funds: $725M → $1.36B (+$630M)

80% more funds holding in top 10

Funds holding in top 10: 59 (+4)

47% more funds holding

Funds holding: 113166 (+53)

14.32% more ownership

Funds ownership: 87.85%102.17% (+14%)

70% less call options, than puts

Call options by funds: $1.96M | Put options by funds: $6.51M

Holders
166
Holders Change
+53
Holders Change %
+46.9%
% of All Funds
2.18%
Holding in Top 10
9
Holding in Top 10 Change
+4
Holding in Top 10 Change %
+80%
% of All Funds
0.12%
New
57
Increased
65
Reduced
22
Closed
4
Calls
$1.96M
Puts
$6.51M
Net Calls
-$4.55M
Net Calls Change
-$15.7M
Name Holding Trade Value Shares
Change
Change in
Stake
RCM
1
RA Capital Management
Massachusetts
$195M
AWG
2
Alpha Wave Global
New York
$168M
VVM
3
Versant Venture Management
California
$124M +$97.7M +2,656,888 New
BlackRock
4
BlackRock
New York
$68.6M +$1.49M +40,643 +3%
Vanguard Group
5
Vanguard Group
Pennsylvania
$62M +$1.44M +39,292 +3%
UBS Group
6
UBS Group
Switzerland
$56M +$11.8M +320,135 +36%
PBA
7
Paradigm Biocapital Advisors
New York
$50M -$23.7M -643,605 -37%
7IH
8
72 Investment Holdings
Connecticut
$47.4M
TCM
9
Tang Capital Management
California
$41.8M
RI
10
RTW Investments
New York
$40.2M
FLAM
11
First Light Asset Management
Minnesota
$32.3M +$25.5M +693,044 New
Adage Capital Partners
12
Adage Capital Partners
Massachusetts
$29.2M -$18.2M -495,120 -44%
Franklin Resources
13
Franklin Resources
California
$27.3M +$21.3M +578,521 +6,756%
Geode Capital Management
14
Geode Capital Management
Massachusetts
$21.2M +$1.43M +38,774 +9%
State Street
15
State Street
Massachusetts
$19.5M +$1.55M +42,256 +11%
Citadel Advisors
16
Citadel Advisors
Florida
$18.6M +$14.4M +390,393 +4,320%
SVCM
17
Saturn V Capital Management
Texas
$17.1M +$951K +25,864 +8%
Invesco
18
Invesco
Georgia
$17M +$3.59M +97,585 +37%
Bank of America
19
Bank of America
North Carolina
$16.3M +$10.3M +281,150 +414%
SB
20
Samsara BioCapital
California
$16M
Point72 Asset Management
21
Point72 Asset Management
Connecticut
$15.8M -$10.2M -278,142 -45%
SPPAM
22
Summit Partners Public Asset Management
Massachusetts
$15.1M +$3.08M +83,857 +35%
Morgan Stanley
23
Morgan Stanley
New York
$13.8M -$10.6M -289,136 -49%
N
24
Nuveen
North Carolina
$13.3M +$3.95M +107,329 +60%
T. Rowe Price Associates
25
T. Rowe Price Associates
Maryland
$11.7M +$8.69M +236,198 +1,582%

LENZ Hedge Fund Activity: Q3 2025 in Review

166 of the 7,621 institutional investors tracked by Wall St. Rank reported a position in LENZ Therapeutics (LENZ) for Q3 2025, worth a combined $1.36B — up 87% from $725M a quarter earlier.

Buyers outnumbered sellers: 57 funds opened new LENZ positions and 4 closed out — a net gain of 53 holders — while 65 added to existing stakes and 22 trimmed.

The largest buyer was Versant Venture Management, opening a new position worth an estimated $97.7M. The largest seller was Sectoral Asset Management, exiting entirely with an estimated $28.6M sold.

  • 166 institutional investors held LENZ Therapeutics (LENZ) as of Q3 2025, up from 113 in Q2 2025.
  • Funds reported $1.36B of LENZ Therapeutics stock for Q3 2025, up 87% quarter-over-quarter.
  • 57 funds opened new LENZ Therapeutics positions in Q3 2025 and 4 closed out, a net change of +53 holders.
  • The largest LENZ Therapeutics buyer in Q3 2025 was Versant Venture Management, an estimated $97.7M added.
  • The largest LENZ Therapeutics seller in Q3 2025 was Sectoral Asset Management, an estimated $28.6M sold.

Based on aggregated 13F filings for Q3 2025.