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LENZ

LENZ Therapeutics

113 hedge funds and large institutions have $725M invested in LENZ Therapeutics in 2025 Q2 according to their latest regulatory filings, with 24 funds opening new positions, 53 increasing their positions, 15 reducing their positions, and 16 closing their positions.

New
Increased
Maintained
Reduced
Closed

3,662% more call options, than puts

Call options by funds: $11.5M | Put options by funds: $305K

253% more repeat investments, than reductions

Existing positions increased: 53 | Existing positions reduced: 15

50% more first-time investments, than exits

New positions opened: 24 | Existing positions closed: 16

34% more capital invested

Capital invested by funds: $542M → $725M (+$183M)

25% more funds holding in top 10

Funds holding in top 10: 45 (+1)

11.34% more ownership

Funds ownership: 76.52%87.85% (+11%)

8% more funds holding

Funds holding: 105113 (+8)

Holders
113
Holders Change
+8
Holders Change %
+7.62%
% of All Funds
1.49%
Holding in Top 10
5
Holding in Top 10 Change
+1
Holding in Top 10 Change %
+25%
% of All Funds
0.07%
New
24
Increased
53
Reduced
15
Closed
16
Calls
$11.5M
Puts
$305K
Net Calls
+$11.2M
Net Calls Change
+$11.2M
Name Holding Trade Value Shares
Change
Change in
Stake
RCM
1
RA Capital Management
Massachusetts
$122M
AWG
2
Alpha Wave Global
New York
$106M
PBA
3
Paradigm Biocapital Advisors
New York
$50.3M +$5.58M +205,134 +14%
BlackRock
4
BlackRock
New York
$42M +$7.23M +265,944 +23%
Vanguard Group
5
Vanguard Group
Pennsylvania
$37.8M +$2.49M +91,532 +8%
Adage Capital Partners
6
Adage Capital Partners
Massachusetts
$32.9M +$15.9M +585,000 +109%
7IH
7
72 Investment Holdings
Connecticut
$29.8M
SAM
8
Sectoral Asset Management
Quebec, Canada
$28.6M
TCM
9
Tang Capital Management
California
$26.3M +$3.55M +130,676 +17%
UBS Group
10
UBS Group
Switzerland
$25.8M +$5.83M +214,317 +32%
RI
11
RTW Investments
New York
$25.3M
Point72 Asset Management
12
Point72 Asset Management
Connecticut
$18.1M -$6.37M -234,102 -27%
Morgan Stanley
13
Morgan Stanley
New York
$17.2M +$10.8M +396,611 +210%
Geode Capital Management
14
Geode Capital Management
Massachusetts
$12.2M +$1.52M +55,730 +15%
State Street
15
State Street
Massachusetts
$11M +$2.4M +88,372 +31%
ABG
16
Ally Bridge Group
New York
$10.1M +$9.34M +343,322 New
SB
17
Samsara BioCapital
California
$10.1M -$4.99M -183,378 -35%
SVCM
18
Saturn V Capital Management
Texas
$10M +$9.31M +342,312 New
Invesco
19
Invesco
Georgia
$7.82M +$7.25M +266,680 New
SPPAM
20
Summit Partners Public Asset Management
Massachusetts
$7.03M +$6.53M +240,000 New
Alyeska Investment Group
21
Alyeska Investment Group
Illinois
$6.36M +$2.04M +75,000 +53%
SM
22
Scoggin Management
New York
$5.86M +$2.72M +100,000 +100%
SC
23
Stempoint Capital
New York
$5.39M +$5M +183,912 New
GIM
24
Granahan Investment Management
Massachusetts
$5.37M +$193K +7,086 +4%
N
25
Nuveen
North Carolina
$5.22M +$3.02M +111,177 +166%

LENZ Hedge Fund Activity: Q2 2025 in Review

113 of the 7,596 institutional investors tracked by Wall St. Rank reported a position in LENZ Therapeutics (LENZ) for Q2 2025, worth a combined $725M — up 34% from $542M a quarter earlier.

Buyers outnumbered sellers: 24 funds opened new LENZ positions and 16 closed out — a net gain of 8 holders — while 53 added to existing stakes and 15 trimmed.

The largest buyer was Adage Capital Partners, adding an estimated $15.9M. The largest seller was T. Rowe Price Associates, cutting an estimated $7.94M.

  • 113 institutional investors held LENZ Therapeutics (LENZ) as of Q2 2025, up from 105 in Q1 2025.
  • Funds reported $725M of LENZ Therapeutics stock for Q2 2025, up 34% quarter-over-quarter.
  • 24 funds opened new LENZ Therapeutics positions in Q2 2025 and 16 closed out, a net change of +8 holders.
  • The largest LENZ Therapeutics buyer in Q2 2025 was Adage Capital Partners, an estimated $15.9M added.
  • The largest LENZ Therapeutics seller in Q2 2025 was T. Rowe Price Associates, an estimated $7.94M sold.

Based on aggregated 13F filings for Q2 2025.