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LENZ

LENZ Therapeutics

145 hedge funds and large institutions have $303M invested in LENZ Therapeutics in 2026 Q1 according to their latest regulatory filings, with 36 funds opening new positions, 56 increasing their positions, 28 reducing their positions, and 47 closing their positions.

New
Increased
Maintained
Reduced
Closed

100% more repeat investments, than reductions

Existing positions increased: 56 | Existing positions reduced: 28

0% more funds holding in top 10

Funds holding in top 10: 33 (0)

6.39% less ownership

Funds ownership: 112.08%105.69% (-6.4%)

9% less funds holding

Funds holding: 160145 (-15)

23% less first-time investments, than exits

New positions opened: 36 | Existing positions closed: 47

46% less capital invested

Capital invested by funds: $562M → $303M (-$258M)

54% less call options, than puts

Call options by funds: $1.1M | Put options by funds: $2.41M

Holders
145
Holders Change
-15
Holders Change %
-9.38%
% of All Funds
1.78%
Holding in Top 10
3
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
0.04%
New
36
Increased
56
Reduced
28
Closed
47
Calls
$1.1M
Puts
$2.41M
Net Calls
-$1.31M
Net Calls Change
+$1.22M
Name Holding Trade Value Shares
Change
Change in
Stake
PM
151
Plustick Management
Virginia
-$3.2M -200,000 Closed
Skandinaviska Enskilda Banken (SEB)
152
Skandinaviska Enskilda Banken (SEB)
Sweden
-$2.97M -185,642 Closed
SA
153
Sovran Advisors
California
-$2.9M -160,134 Closed
AIC
154
AWM Investment Company
New York
-$2.4M -150,000 Closed
Ameriprise
155
Ameriprise
Minnesota
-$2.19M -136,896 Closed
Nomura Asset Management
156
Nomura Asset Management
Japan
-$1.55M -96,780 Closed
Wealth Enhancement Advisory Services
157
Wealth Enhancement Advisory Services
Minnesota
-$1.4M -83,243 Closed
Citadel Advisors
158
Citadel Advisors
Florida
-$1.13M -80,574 Closed
VC
159
VarCov Co
Connecticut
-$1.26M -78,831 Closed
Two Sigma Advisers
160
Two Sigma Advisers
New York
-$1.24M -77,426 Closed
Ensign Peak Advisors
161
Ensign Peak Advisors
Utah
-$1.24M -77,275 Closed
AG
162
Algert Global
California
-$1.22M -76,025 Closed
Federated Hermes
163
Federated Hermes
Pennsylvania
-$1M -62,636 Closed
PBM
164
Propel Bio Management
California
-$945K -59,085 Closed
Wellington Management Group
165
Wellington Management Group
Massachusetts
-$870K -54,402 Closed
PA
166
Perceptive Advisors
New York
-$800K -50,000 Closed
Jane Street
167
Jane Street
New York
-$658K -46,847 Closed
Verition Fund Management
168
Verition Fund Management
Connecticut
-$740K -46,268 Closed
Qube Research & Technologies (QRT)
169
Qube Research & Technologies (QRT)
United Kingdom
-$709K -44,290 Closed
ACM
170
Aquatic Capital Management
Illinois
-$684K -42,729 Closed
SAM
171
Sectoral Asset Management
Quebec, Canada
-$680K -42,500 Closed
Manulife (Manufacturers Life Insurance)
172
Manulife (Manufacturers Life Insurance)
Ontario, Canada
-$335K -20,816 Closed
A
173
AlphaQuest
New York
-$314K -19,613 Closed
SAM
174
Simplify Asset Management
Nevada
-$280K -17,481 Closed
QT
175
Quantbot Technologies
New York
-$270K -16,879 Closed

LENZ Hedge Fund Activity: Q1 2026 in Review

145 of the 8,126 institutional investors tracked by Wall St. Rank reported a position in LENZ Therapeutics (LENZ) for Q1 2026, worth a combined $303M — down 46% from $562M a quarter earlier.

Sellers outnumbered buyers: 47 funds closed out of LENZ and 36 opened new positions — a net loss of 11 holders — while 28 trimmed existing stakes and 56 added.

The largest buyer was Squarepoint, adding an estimated $14.3M. The largest seller was UBS Group, cutting an estimated $19.9M.

  • 145 institutional investors held LENZ Therapeutics (LENZ) as of Q1 2026, down from 160 in Q4 2025.
  • Funds reported $303M of LENZ Therapeutics stock for Q1 2026, down 46% quarter-over-quarter.
  • 36 funds opened new LENZ Therapeutics positions in Q1 2026 and 47 closed out, a net change of -11 holders.
  • The largest LENZ Therapeutics buyer in Q1 2026 was Squarepoint, an estimated $14.3M added.
  • The largest LENZ Therapeutics seller in Q1 2026 was UBS Group, an estimated $19.9M sold.

Based on aggregated 13F filings for Q1 2026.