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Kyverna Therapeutics

75 hedge funds and large institutions have $136M invested in Kyverna Therapeutics in 2025 Q3 according to their latest regulatory filings, with 10 funds opening new positions, 18 increasing their positions, 29 reducing their positions, and 14 closing their positions.

New
Increased
Maintained
Reduced
Closed

106,800% more call options, than puts

Call options by funds: $1.07M | Put options by funds: $1K

91% more capital invested

Capital invested by funds: $71.4M → $136M (+$64.9M)

0% more funds holding in top 10

Funds holding in top 10: 33 (0)

1.22% less ownership

Funds ownership: 53.7%52.48% (-1.2%)

5% less funds holding

Funds holding: 7975 (-4)

29% less first-time investments, than exits

New positions opened: 10 | Existing positions closed: 14

38% less repeat investments, than reductions

Existing positions increased: 18 | Existing positions reduced: 29

Holders
75
Holders Change
-4
Holders Change %
-5.06%
% of All Funds
0.98%
Holding in Top 10
3
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
0.04%
New
10
Increased
18
Reduced
29
Closed
14
Calls
$1.07M
Puts
$1K
Net Calls
+$1.07M
Net Calls Change
+$741K
Name Holding Trade Value Shares
Change
Change in
Stake
VVA
1
Vida Ventures Advisors
Massachusetts
$27.1M
GS
2
Gilead Sciences
California
$24.8M
BCLSI
3
Bain Capital Life Sciences Investors
Massachusetts
$20.2M
T. Rowe Price Associates
4
T. Rowe Price Associates
Maryland
$9.07M -$1.27M -318,302 -17%
Vanguard Group
5
Vanguard Group
Pennsylvania
$7.94M +$39.4K +9,858 +0.8%
IHG
6
Insight Holdings Group
New York
$5.93M
Franklin Resources
7
Franklin Resources
California
$4.07M -$69.7K -17,440 -3%
MPM
8
MBB Public Markets
Illinois
$3.69M
CCM
9
Catalio Capital Management
New York
$3.52M
Millennium Management
10
Millennium Management
New York
$3.31M +$396K +99,075 +22%
BlackRock
11
BlackRock
New York
$2.89M -$206K -51,413 -10%
KCP
12
Kera Capital Partners
California
$2.53M
PLC
13
Peapod Lane Capital
New York
$1.91M -$312K -78,003 -20%
Geode Capital Management
14
Geode Capital Management
Massachusetts
$1.67M -$37.1K -9,272 -3%
WP
15
Woodline Partners
California
$1.51M +$1.01M +252,212 New
Susquehanna International Group
16
Susquehanna International Group
Pennsylvania
$1.22M +$521K +130,421 +180%
Jane Street
17
Jane Street
New York
$1.19M +$444K +111,082 +127%
BCM
18
Bridgeway Capital Management
Texas
$1.05M +$448K +112,000 +178%
Morgan Stanley
19
Morgan Stanley
New York
$1.05M -$111K -27,835 -14%
TD Asset Management
20
TD Asset Management
Ontario, Canada
$989K -$349K -87,400 -35%
Renaissance Technologies
21
Renaissance Technologies
New York
$988K +$169K +42,197 +34%
UBS Group
22
UBS Group
Switzerland
$945K +$237K +59,264 +60%
Jacobs Levy Equity Management
23
Jacobs Levy Equity Management
New Jersey
$886K +$591K +147,712 New
Two Sigma Investments
24
Two Sigma Investments
New York
$795K +$47.4K +11,867 +10%
Charles Schwab
25
Charles Schwab
California
$753K +$27.9K +6,972 +6%

KYTX Hedge Fund Activity: Q3 2025 in Review

75 of the 7,621 institutional investors tracked by Wall St. Rank reported a position in Kyverna Therapeutics (KYTX) for Q3 2025, worth a combined $136M — up 91% from $71.4M a quarter earlier.

Sellers outnumbered buyers: 14 funds closed out of KYTX and 10 opened new positions — a net loss of 4 holders — while 29 trimmed existing stakes and 18 added.

The largest buyer was Woodline Partners, opening a new position worth an estimated $1.01M. The largest seller was T. Rowe Price Associates, cutting an estimated $1.27M.

  • 75 institutional investors held Kyverna Therapeutics (KYTX) as of Q3 2025, down from 79 in Q2 2025.
  • Funds reported $136M of Kyverna Therapeutics stock for Q3 2025, up 91% quarter-over-quarter.
  • 10 funds opened new Kyverna Therapeutics positions in Q3 2025 and 14 closed out, a net change of -4 holders.
  • The largest Kyverna Therapeutics buyer in Q3 2025 was Woodline Partners, an estimated $1.01M added.
  • The largest Kyverna Therapeutics seller in Q3 2025 was T. Rowe Price Associates, an estimated $1.27M sold.

Based on aggregated 13F filings for Q3 2025.