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Kyverna Therapeutics

87 hedge funds and large institutions have $50M invested in Kyverna Therapeutics in 2025 Q1 according to their latest regulatory filings, with 14 funds opening new positions, 27 increasing their positions, 25 reducing their positions, and 15 closing their positions.

New
Increased
Maintained
Reduced
Closed

8% more repeat investments, than reductions

Existing positions increased: 27 | Existing positions reduced: 25

0% more funds holding in top 10

Funds holding in top 10: 33 (0)

0% more call options, than puts

Call options by funds: $3K | Put options by funds: $3K

7% less first-time investments, than exits

New positions opened: 14 | Existing positions closed: 15

1% less funds holding

Funds holding: 8887 (-1)

7.16% less ownership

Funds ownership: 66.88%59.71% (-7.2%)

54% less capital invested

Capital invested by funds: $108M → $50M (-$58.1M)

Holders
87
Holders Change
-1
Holders Change %
-1.14%
% of All Funds
1.17%
Holding in Top 10
3
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
0.04%
New
14
Increased
27
Reduced
25
Closed
15
Calls
$3K
Puts
$3K
Net Calls
Net Calls Change
-$196K
Name Holding Trade Value Shares
Change
Change in
Stake
VVA
1
Vida Ventures Advisors
Massachusetts
$8.73M
GS
2
Gilead Sciences
California
$7.96M
BCLSI
3
Bain Capital Life Sciences Investors
Massachusetts
$6.5M
NHAS
4
Novo Holdings A/S
Denmark
$3.57M
BlackRock
5
BlackRock
New York
$3.24M +$11.2K +3,775 +0.2%
Vanguard Group
6
Vanguard Group
Pennsylvania
$2.51M -$43.7K -14,783 -1%
Citadel Advisors
7
Citadel Advisors
Florida
$1.92M +$2.46M +831,301 +512%
IHG
8
Insight Holdings Group
New York
$1.91M +$225K +76,139 +8%
Franklin Resources
9
Franklin Resources
California
$1.34M
MPM
10
MBB Public Markets
Illinois
$1.19M
CCM
11
Catalio Capital Management
New York
$1.13M
T. Rowe Price Associates
12
T. Rowe Price Associates
Maryland
$1.12M -$41.6K -14,084 -2%
Geode Capital Management
13
Geode Capital Management
Massachusetts
$1.09M +$71.8K +24,292 +5%
PLC
14
Peapod Lane Capital
New York
$765K +$1.17M +396,221 New
KCP
15
Kera Capital Partners
California
$726K +$163 +55 +0%
State Street
16
State Street
Massachusetts
$723K -$15.7K -5,310 -1%
Millennium Management
17
Millennium Management
New York
$460K -$1.5M -508,282 -68%
Northern Trust
18
Northern Trust
Illinois
$370K -$11.9K -4,030 -2%
SCM
19
Superstring Capital Management
New York
$369K +$26.9K +9,110 +5%
UBS Group
20
UBS Group
Switzerland
$343K -$76K -25,733 -13%
Charles Schwab
21
Charles Schwab
California
$319K -$13K -4,410 -3%
BCM
22
Bridgeway Capital Management
Texas
$263K +$166K +56,300 +70%
Morgan Stanley
23
Morgan Stanley
New York
$260K -$194K -65,684 -33%
Renaissance Technologies
24
Renaissance Technologies
New York
$241K +$237K +80,258 +180%
Two Sigma Investments
25
Two Sigma Investments
New York
$237K -$173K -58,677 -32%

KYTX Hedge Fund Activity: Q1 2025 in Review

87 of the 7,459 institutional investors tracked by Wall St. Rank reported a position in Kyverna Therapeutics (KYTX) for Q1 2025, worth a combined $50M — down 54% from $108M a quarter earlier.

Sellers outnumbered buyers: 15 funds closed out of KYTX and 14 opened new positions — a net loss of 1 holder — while 25 trimmed existing stakes and 27 added.

The largest buyer was Citadel Advisors, adding an estimated $2.46M. The largest seller was JP Morgan Chase, cutting an estimated $6.28M.

  • 87 institutional investors held Kyverna Therapeutics (KYTX) as of Q1 2025, down from 88 in Q4 2024.
  • Funds reported $50M of Kyverna Therapeutics stock for Q1 2025, down 54% quarter-over-quarter.
  • 14 funds opened new Kyverna Therapeutics positions in Q1 2025 and 15 closed out, a net change of -1 holder.
  • The largest Kyverna Therapeutics buyer in Q1 2025 was Citadel Advisors, an estimated $2.46M added.
  • The largest Kyverna Therapeutics seller in Q1 2025 was JP Morgan Chase, an estimated $6.28M sold.

Based on aggregated 13F filings for Q1 2025.