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Kyverna Therapeutics
KYTX

111 hedge funds and large institutions have $301M invested in Kyverna Therapeutics in 2026 Q1 according to their latest regulatory filings, with 27 funds opening new positions, 31 increasing their positions, 35 reducing their positions, and 14 closing their positions.

New
Increased
Maintained
Reduced
Closed

202% more call options, than puts

Call options by funds: $1.41M | Put options by funds: $468K

93% more first-time investments, than exits

New positions opened: 27 | Existing positions closed: 14

12% more funds holding

Funds holding: 99 → 111 (+12)

0% more funds holding in top 10

Funds holding in top 10: 6 → 6 (0)

6% less capital invested

Capital invested by funds: $321M → $301M (-$20.2M)

11% less repeat investments, than reductions

Existing positions increased: 31 | Existing positions reduced: 35

20.32% less ownership

Funds ownership: 77.93% → 57.62% (-20%)

Holders
111
Holders Change
+12
Holders Change %
+12.12%
% of All Funds
1.37%
Holding in Top 10
6
Holding in Top 10 Change
–
Holding in Top 10 Change %
–
% of All Funds
0.07%
New
27
Increased
31
Reduced
35
Closed
14
Calls
$1.41M
Puts
$468K
Net Calls
+$946K
Net Calls Change
+$1.17M

Top Buyers

Rank Fund Capital Flow
1
ACM
AIGH Capital Management
Maryland
+$4.17M
2
Marshall Wace
Marshall Wace
United Kingdom
+$3.92M
3
Millennium Management
Millennium Management
New York
+$3.43M
4
Susquehanna International Group
Susquehanna International Group
Pennsylvania
+$2.82M
5
BlackRock
BlackRock
New York
+$2.77M

Top Sellers

Rank Fund Capital Flow
1
Adage Capital Partners
Adage Capital Partners
Massachusetts
-$9.72M
2
Alyeska Investment Group
Alyeska Investment Group
Illinois
-$5.64M
3
RA
RFG Advisory
Alabama
-$4.18M
4
HCM
Heights Capital Management
California
-$2.56M
5
MIM
Monashee Investment Management
Massachusetts
-$1.83M
Name Holding Trade Value Shares
Change 		Change in
Stake
Point72 Asset Management
26
Point72 Asset Management
Connecticut
$1.92M +$1.59M +190,745 +593%
Goldman Sachs
27
Goldman Sachs
New York
$1.84M +$661K +79,380 +59%
Charles Schwab
28
Charles Schwab
California
$1.82M +$714K +85,662 +68%
BGM
29
Burkehill Global Management
New York
$1.73M – – –
Invesco
30
Invesco
Georgia
$1.61M +$1.56M +186,674 New
Two Sigma Investments
31
Two Sigma Investments
New York
$1.57M -$197K -23,652 -12%
SAM
32
Simplify Asset Management
Nevada
$1.49M -$160K -19,233 -10%
TD Asset Management
33
TD Asset Management
Ontario, Canada
$1.46M -$448K -53,714 -24%
BCM
34
Bridgeway Capital Management
Texas
$1.29M -$208K -25,000 -14%
Squarepoint
35
Squarepoint
New York
$1.27M +$67.6K +8,110 +6%
State Street
36
State Street
Massachusetts
$1.19M +$392K +47,000 +51%
Barclays
37
Barclays
United Kingdom
$1.18M -$236K -28,293 -17%
Manulife (Manufacturers Life Insurance)
38
Manulife (Manufacturers Life Insurance)
Ontario, Canada
$1.16M – – –
Stifel Financial
39
Stifel Financial
Missouri
$1.13M +$39.4K +4,734 +4%
YIH
40
Y-Intercept (HK)
Hong Kong
$991K +$957K +114,841 New
Wells Fargo
41
Wells Fargo
California
$987K +$329K +39,450 +53%
WB
42
WesBanco Bank
West Virginia
$952K +$919K +110,300 New
KCP
43
Kera Capital Partners
California
$933K -$204K -24,520 -18%
Jane Street
44
Jane Street
New York
$899K -$649K -77,879 -43%
6CM
45
683 Capital Management
New York
$734K -$249K -29,900 -26%
Dimensional Fund Advisors
46
Dimensional Fund Advisors
Texas
$677K +$50 +6 +0%
Northern Trust
47
Northern Trust
Illinois
$674K +$221K +26,470 +51%
Hudson Bay Capital Management
48
Hudson Bay Capital Management
Connecticut
$613K -$146K -17,494 -20%
Citadel Advisors
49
Citadel Advisors
Florida
$502K -$1.81M -217,320 -79%
Bank of America
50
Bank of America
North Carolina
$481K +$225K +27,019 +94%
1
2
3 4 5

KYTX Hedge Fund Activity: Q1 2026 in Review

111 of the 8,128 institutional investors tracked by Wall St. Rank reported a position in Kyverna Therapeutics (KYTX) for Q1 2026, worth a combined $301M — down 6.3% from $321M a quarter earlier.

Buyers outnumbered sellers: 27 funds opened new KYTX positions and 14 closed out — a net gain of 13 holders — while 31 added to existing stakes and 35 trimmed.

The largest buyer was AIGH Capital Management, adding an estimated $4.17M. The largest seller was Adage Capital Partners, cutting an estimated $9.72M.

  • 111 institutional investors held Kyverna Therapeutics (KYTX) as of Q1 2026, up from 99 in Q4 2025.
  • Funds reported $301M of Kyverna Therapeutics stock for Q1 2026, down 6.3% quarter-over-quarter.
  • 27 funds opened new Kyverna Therapeutics positions in Q1 2026 and 14 closed out, a net change of +13 holders.
  • The largest Kyverna Therapeutics buyer in Q1 2026 was AIGH Capital Management, an estimated $4.17M added.
  • The largest Kyverna Therapeutics seller in Q1 2026 was Adage Capital Partners, an estimated $9.72M sold.

Based on aggregated 13F filings for Q1 2026.