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Kyverna Therapeutics

79 hedge funds and large institutions have $71.4M invested in Kyverna Therapeutics in 2025 Q2 according to their latest regulatory filings, with 16 funds opening new positions, 29 increasing their positions, 24 reducing their positions, and 24 closing their positions.

New
Increased
Maintained
Reduced
Closed

43% more capital invested

Capital invested by funds: $50M → $71.4M (+$21.4M)

21% more repeat investments, than reductions

Existing positions increased: 29 | Existing positions reduced: 24

0% more funds holding in top 10

Funds holding in top 10: 33 (0)

6.02% less ownership

Funds ownership: 59.71%53.7% (-6%)

9% less funds holding

Funds holding: 8779 (-8)

33% less first-time investments, than exits

New positions opened: 16 | Existing positions closed: 24

Holders
79
Holders Change
-8
Holders Change %
-9.2%
% of All Funds
1.04%
Holding in Top 10
3
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
0.04%
New
16
Increased
29
Reduced
24
Closed
24
Calls
$327K
Puts
Net Calls
+$327K
Net Calls Change
+$327K
Name Holding Trade Value Shares
Change
Change in
Stake
UBS Group
26
UBS Group
Switzerland
$301K -$197K -79,512 -45%
Two Sigma Advisers
27
Two Sigma Advisers
New York
$290K +$33.1K +13,400 +17%
State Street
28
State Street
Massachusetts
$280K -$701K -283,278 -76%
Jane Street
29
Jane Street
New York
$269K +$217K +87,769 New
Susquehanna International Group
30
Susquehanna International Group
Pennsylvania
$222K +$93.5K +37,816 +110%
DekaBank Deutsche Girozentrale
31
DekaBank Deutsche Girozentrale
Germany
$196K
BCM
32
Bridgeway Capital Management
Texas
$193K -$182K -73,400 -54%
Marshall Wace
33
Marshall Wace
United Kingdom
$191K +$92.7K +37,496 +153%
Point72 Asset Management
34
Point72 Asset Management
Connecticut
$170K +$137K +55,522 New
Northern Trust
35
Northern Trust
Illinois
$159K -$346K -139,986 -73%
Barclays
36
Barclays
United Kingdom
$155K -$76.7K -30,996 -38%
Federated Hermes
37
Federated Hermes
Pennsylvania
$135K +$19.8K +8,000 +22%
YIH
38
Y-Intercept (HK)
Hong Kong
$129K +$104K +42,025 New
Stifel Financial
39
Stifel Financial
Missouri
$120K -$490 -198 -0.5%
PCM
40
Prelude Capital Management
New York
$111K -$77.4K -31,299 -46%
XT
41
XTX Topco
Cayman Islands
$107K +$86.4K +34,939 New
Bank of America
42
Bank of America
North Carolina
$104K +$40.6K +16,430 +95%
Squarepoint
43
Squarepoint
New York
$91.3K +$73.5K +29,730 New
JP Morgan Chase
44
JP Morgan Chase
New York
$85.5K -$28.8K -11,647 -29%
JG
45
Jain Global
New York
$80.6K +$64.9K +26,243 New
CC
46
Caxton Corporation
New Jersey
$70.6K
HF
47
HRT Financial
New York
$61K +$49.9K +20,171 New
VPIM
48
Vanguard Personalized Indexing Management
California
$58.7K +$9.52K +3,847 +25%
EI
49
Ethic Inc
New York
$55.9K +$42.1K +17,036 New
Citigroup
50
Citigroup
New York
$48.6K -$8.21K -3,321 -17%

KYTX Hedge Fund Activity: Q2 2025 in Review

79 of the 7,596 institutional investors tracked by Wall St. Rank reported a position in Kyverna Therapeutics (KYTX) for Q2 2025, worth a combined $71.4M — up 43% from $50M a quarter earlier.

Sellers outnumbered buyers: 24 funds closed out of KYTX and 16 opened new positions — a net loss of 8 holders — while 24 trimmed existing stakes and 29 added.

The largest buyer was T. Rowe Price Associates, adding an estimated $3.09M. The largest seller was Novo Holdings A/S, exiting entirely with an estimated $3.57M sold.

  • 79 institutional investors held Kyverna Therapeutics (KYTX) as of Q2 2025, down from 87 in Q1 2025.
  • Funds reported $71.4M of Kyverna Therapeutics stock for Q2 2025, up 43% quarter-over-quarter.
  • 16 funds opened new Kyverna Therapeutics positions in Q2 2025 and 24 closed out, a net change of -8 holders.
  • The largest Kyverna Therapeutics buyer in Q2 2025 was T. Rowe Price Associates, an estimated $3.09M added.
  • The largest Kyverna Therapeutics seller in Q2 2025 was Novo Holdings A/S, an estimated $3.57M sold.

Based on aggregated 13F filings for Q2 2025.