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Kyverna Therapeutics

87 hedge funds and large institutions have $50M invested in Kyverna Therapeutics in 2025 Q1 according to their latest regulatory filings, with 14 funds opening new positions, 27 increasing their positions, 25 reducing their positions, and 15 closing their positions.

New
Increased
Maintained
Reduced
Closed

8% more repeat investments, than reductions

Existing positions increased: 27 | Existing positions reduced: 25

0% more funds holding in top 10

Funds holding in top 10: 33 (0)

0% more call options, than puts

Call options by funds: $3K | Put options by funds: $3K

7% less first-time investments, than exits

New positions opened: 14 | Existing positions closed: 15

1% less funds holding

Funds holding: 8887 (-1)

7.16% less ownership

Funds ownership: 66.88%59.71% (-7.2%)

54% less capital invested

Capital invested by funds: $108M → $50M (-$58.1M)

Holders
87
Holders Change
-1
Holders Change %
-1.14%
% of All Funds
1.17%
Holding in Top 10
3
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
0.04%
New
14
Increased
27
Reduced
25
Closed
15
Calls
$3K
Puts
$3K
Net Calls
Net Calls Change
-$196K
Name Holding Trade Value Shares
Change
Change in
Stake
Goldman Sachs
26
Goldman Sachs
New York
$202K -$26.6K -9,014 -8%
DekaBank Deutsche Girozentrale
27
DekaBank Deutsche Girozentrale
Germany
$181K
TD Asset Management
28
TD Asset Management
Ontario, Canada
$174K
Barclays
29
Barclays
United Kingdom
$157K -$24.2K -8,196 -9%
Two Sigma Advisers
30
Two Sigma Advisers
New York
$156K +$1.8K +610 +0.8%
AQR Capital Management
31
AQR Capital Management
Connecticut
$137K +$210K +71,057 New
CSS
32
Cubist Systematic Strategies
Connecticut
$132K +$48.1K +16,267 +31%
PCM
33
Prelude Capital Management
New York
$130K +$70.3K +23,784 +54%
Bank of New York Mellon
34
Bank of New York Mellon
New York
$94.2K +$26.2K +8,851 +22%
N
35
Nuveen
North Carolina
$91.7K +$72.9K +24,660 +108%
BNP Paribas Financial Markets
36
BNP Paribas Financial Markets
France
$89.5K +$4.13K +1,398 +3%
JP Morgan Chase
37
JP Morgan Chase
New York
$76.2K -$6.28M -2,126,935 -98%
Stifel Financial
38
Stifel Financial
Missouri
$75.6K -$529 -179 -0.5%
Manulife (Manufacturers Life Insurance)
39
Manulife (Manufacturers Life Insurance)
Ontario, Canada
$74.5K +$2.39K +808 +2%
Wellington Management Group
40
Wellington Management Group
Massachusetts
$73K -$699K -236,586 -86%
Federated Hermes
41
Federated Hermes
Pennsylvania
$69.5K +$11.8K +4,000 +13%
Susquehanna International Group
42
Susquehanna International Group
Pennsylvania
$66.5K +$64.7K +21,880 +174%
AA
43
ALPS Advisors
Colorado
$62K -$8.23K -2,786 -8%
RhumbLine Advisers
44
RhumbLine Advisers
Massachusetts
$61K +$16.8K +5,694 +22%
AllianceBernstein
45
AllianceBernstein
Tennessee
$57.9K
SEI Investments
46
SEI Investments
Pennsylvania
$47.6K +$72.9K +24,660 New
Marshall Wace
47
Marshall Wace
United Kingdom
$47.4K +$27.5K +9,320 +61%
CC
48
Caxton Corporation
New Jersey
$44.4K
IIM
49
INTECH Investment Management
Florida
$42.4K +$64.8K +21,945 New
Citigroup
50
Citigroup
New York
$37K -$3.46K -1,172 -6%

KYTX Hedge Fund Activity: Q1 2025 in Review

87 of the 7,459 institutional investors tracked by Wall St. Rank reported a position in Kyverna Therapeutics (KYTX) for Q1 2025, worth a combined $50M — down 54% from $108M a quarter earlier.

Sellers outnumbered buyers: 15 funds closed out of KYTX and 14 opened new positions — a net loss of 1 holder — while 25 trimmed existing stakes and 27 added.

The largest buyer was Citadel Advisors, adding an estimated $2.46M. The largest seller was JP Morgan Chase, cutting an estimated $6.28M.

  • 87 institutional investors held Kyverna Therapeutics (KYTX) as of Q1 2025, down from 88 in Q4 2024.
  • Funds reported $50M of Kyverna Therapeutics stock for Q1 2025, down 54% quarter-over-quarter.
  • 14 funds opened new Kyverna Therapeutics positions in Q1 2025 and 15 closed out, a net change of -1 holder.
  • The largest Kyverna Therapeutics buyer in Q1 2025 was Citadel Advisors, an estimated $2.46M added.
  • The largest Kyverna Therapeutics seller in Q1 2025 was JP Morgan Chase, an estimated $6.28M sold.

Based on aggregated 13F filings for Q1 2025.