|
1
|
Baker Bros. Advisors
New York
|
$54.2M
|
–
|
–
|
–
|
|
|
2
|
HHLR Advisors
Grand Cayman,
Cayman Islands
|
$33.2M
|
+$8.63M
|
+447,000
|
+32%
|
|
|
3
|
ArrowMark Colorado Holdings
Denver,
Colorado
|
$29.1M
|
+$31.1M
|
+1,610,181
|
New
|
|
|
4
|
Deerfield Management
New York
|
$23.7M
|
+$3.5M
|
+181,437
|
+16%
|
|
|
5
|
Vanguard Group
Malvern,
Pennsylvania
|
$22.5M
|
+$6.53M
|
+337,951
|
+37%
|
|
|
6
|
|
$17.5M
|
+$6.24M
|
+322,908
|
+50%
|
|
|
7
|
Sofinnova Investments
Menlo Park,
California
|
$16.7M
|
–
|
–
|
–
|
|
|
8
|
Vivo Capital
Palo Alto,
California
|
$15.2M
|
+$11.2M
|
+578,600
|
+218%
|
|
|
9
|
Fidelity Investments
Boston,
Massachusetts
|
$11.5M
|
–
|
–
|
–
|
|
|
10
|
VHCP Management II
New York
|
$11.5M
|
–
|
–
|
–
|
|
|
11
|
Ameriprise
Minneapolis,
Minnesota
|
$9.66M
|
+$4.48M
|
+231,985
|
+77%
|
|
|
12
|
VHCP Management III
New York
|
$5.92M
|
–
|
–
|
–
|
|
|
13
|
Eventide Asset Management
Boston,
Massachusetts
|
$5.76M
|
–
|
–
|
–
|
|
|
14
|
Boxer Capital
San Diego,
California
|
$5.25M
|
–
|
–
|
–
|
|
|
15
|
Cormorant Asset Management
Boston,
Massachusetts
|
$4.88M
|
-$10.8M
|
-561,000
|
-68%
|
|
|
16
|
Geode Capital Management
Boston,
Massachusetts
|
$2.71M
|
+$1.03M
|
+53,345
|
+55%
|
|
|
17
|
Northern Trust
Chicago,
Illinois
|
$2.39M
|
+$1.04M
|
+53,670
|
+68%
|
|
|
18
|
Alyeska Investment Group
Chicago,
Illinois
|
$2.38M
|
+$2.54M
|
+131,502
|
New
|
|
|
19
|
State Street
Boston,
Massachusetts
|
$2.28M
|
+$860K
|
+44,499
|
+54%
|
|
|
20
|
Citadel Advisors
Miami,
Florida
|
$2.27M
|
+$1.73M
|
+89,628
|
+247%
|
|
|
21
|
|
$1.72M
|
+$1.66M
|
+85,714
|
+898%
|
|
|
22
|
Hudson Bay Capital Management
Stamford,
Connecticut
|
$1.63M
|
+$1.74M
|
+90,000
|
New
|
|
|
23
|
Victory Capital Management
San Antonio,
Texas
|
$1.53M
|
-$18.2K
|
-940
|
-1%
|
|
|
24
|
Spark Investment Management
New York
|
$1.22M
|
+$922K
|
+47,727
|
+239%
|
|
|
25
|
Nexthera Capital
New York
|
$1.22M
|
+$1.31M
|
+67,692
|
New
|
|
