|
1
|
Baker Bros. Advisors
New York
|
$76.5M
|
–
|
–
|
–
|
|
|
2
|
Hillhouse Investment Management
Grand Cayman,
Cayman Islands
|
$35.4M
|
-$84.5M
|
-4,347,639
|
-76%
|
|
|
3
|
Boxer Capital
San Diego,
California
|
$29.9M
|
–
|
–
|
–
|
|
|
4
|
Deerfield Management
New York
|
$27.1M
|
-$3.21M
|
-164,934
|
-13%
|
|
|
5
|
ArrowMark Colorado Holdings
Denver,
Colorado
|
$26.5M
|
+$20.3M
|
+1,042,093
|
+693%
|
|
|
6
|
Sofinnova Investments
Menlo Park,
California
|
$23.5M
|
–
|
–
|
–
|
|
|
7
|
Cormorant Asset Management
Boston,
Massachusetts
|
$21.2M
|
–
|
–
|
–
|
|
|
8
|
Fidelity Investments
Boston,
Massachusetts
|
$19M
|
-$2.44M
|
-125,307
|
-14%
|
|
|
9
|
VHCP Management II
New York
|
$16.3M
|
–
|
–
|
–
|
|
|
10
|
Vanguard Group
Malvern,
Pennsylvania
|
$14.2M
|
+$7.89M
|
+405,991
|
+271%
|
|
|
11
|
|
$11.5M
|
+$8.57M
|
+440,573
|
+4,406%
|
|
|
12
|
Ameriprise
Minneapolis,
Minnesota
|
$9.43M
|
-$6.86M
|
-352,609
|
-49%
|
|
|
13
|
VHCP Management III
New York
|
$8.36M
|
+$6.37M
|
+327,777
|
New
|
|
|
14
|
Eventide Asset Management
Boston,
Massachusetts
|
$8.13M
|
+$439K
|
+22,600
|
+8%
|
|
|
15
|
Vivo Capital
Palo Alto,
California
|
$6.75M
|
+$1.53M
|
+78,805
|
+42%
|
|
|
16
|
Millennium Management
New York
|
$5.66M
|
+$3.88M
|
+199,631
|
+890%
|
|
|
17
|
Victory Capital Management
San Antonio,
Texas
|
$3.43M
|
-$144K
|
-7,390
|
-5%
|
|
|
18
|
Laurion Capital Management
New York
|
$2.83M
|
–
|
–
|
–
|
|
|
19
|
Geode Capital Management
Boston,
Massachusetts
|
$2.48M
|
+$1.89M
|
+97,123
|
New
|
|
|
20
|
Foresite Capital Management IV
Larkspur,
California
|
$2.41M
|
–
|
–
|
–
|
|
|
21
|
Northern Trust
Chicago,
Illinois
|
$2.01M
|
+$1.53M
|
+78,942
|
New
|
|
|
22
|
State Street
Boston,
Massachusetts
|
$1.65M
|
+$1.25M
|
+64,499
|
New
|
|
|
23
|
Citadel Advisors
Miami,
Florida
|
$1.37M
|
-$700K
|
-36,023
|
-40%
|
|
|
24
|
Perceptive Advisors
New York
|
$1.36M
|
-$1.13M
|
-57,942
|
-52%
|
|
|
25
|
ALPS Advisors
Denver,
Colorado
|
$711K
|
+$126K
|
+6,491
|
+30%
|
|
