|
1
|
Deerfield Management
New York
|
$51.8M
|
+$29.9M
|
+1,143,549
|
+112%
|
|
|
2
|
RA Capital Management
Boston,
Massachusetts
|
$46.3M
|
+$41.3M
|
+1,580,322
|
+452%
|
|
|
3
|
Vivo Capital
Palo Alto,
California
|
$44.6M
|
–
|
–
|
–
|
|
|
4
|
Wellington Management Group
Boston,
Massachusetts
|
$43M
|
+$7.47M
|
+285,493
|
+19%
|
|
|
5
|
Franklin Resources
San Mateo,
California
|
$34.9M
|
+$4.4M
|
+168,132
|
+13%
|
|
|
6
|
|
$34.2M
|
-$3.48M
|
-133,066
|
-9%
|
|
|
7
|
State Street
Boston,
Massachusetts
|
$33.6M
|
+$21.2M
|
+809,029
|
+137%
|
|
|
8
|
Suvretta Capital Management
New York
|
$28.5M
|
+$6.05M
|
+231,209
|
+24%
|
|
|
9
|
Janus Henderson Group
London,
|
$28M
|
+$937K
|
+35,828
|
+3%
|
|
|
10
|
Fidelity Investments
Boston,
Massachusetts
|
$26.1M
|
-$6.78M
|
-259,180
|
-19%
|
|
|
11
|
Vanguard Group
Malvern,
Pennsylvania
|
$23.1M
|
+$914K
|
+34,938
|
+4%
|
|
|
12
|
Adage Capital Partners
Boston,
Massachusetts
|
$21.2M
|
+$2.09M
|
+80,000
|
+10%
|
|
|
13
|
Eventide Asset Management
Boston,
Massachusetts
|
$15.9M
|
-$18.5M
|
-707,319
|
-52%
|
|
|
14
|
Nicholas Investment Partners
Rancho Santa Fe,
California
|
$15.6M
|
+$1.49M
|
+56,773
|
+10%
|
|
|
15
|
Polar Capital Holdings
London,
United Kingdom
|
$14.8M
|
-$10.2M
|
-389,875
|
-39%
|
|
|
16
|
Emerald Mutual Fund Advisers Trust
Leola,
Pennsylvania
|
$9.73M
|
-$262K
|
-10,000
|
-2%
|
|
|
17
|
Emerald Advisers
Leola,
Pennsylvania
|
$8.98M
|
-$593K
|
-22,650
|
-6%
|
|
|
18
|
Geode Capital Management
Boston,
Massachusetts
|
$8.08M
|
+$262K
|
+10,010
|
+3%
|
|
|
19
|
International Biotechnology Trust
London,
United Kingdom
|
$6.79M
|
+$1.8M
|
+68,700
|
+32%
|
|
|
20
|
American Century Companies
Kansas City,
Missouri
|
$6.58M
|
+$1.48M
|
+56,605
|
+26%
|
|
|
21
|
Northern Trust
Chicago,
Illinois
|
$5.79M
|
+$344K
|
+13,163
|
+6%
|
|
|
22
|
Commodore Capital
New York
|
$5.43M
|
+$319K
|
+12,204
|
+6%
|
|
|
23
|
Stonepine Capital Management
Bend,
Oregon
|
$4.79M
|
-$5.82M
|
-222,310
|
-53%
|
|
|
24
|
Prosight Management
Dallas,
Texas
|
$4.34M
|
+$4.74M
|
+181,171
|
New
|
|
|
25
|
Dimensional Fund Advisors
Austin,
Texas
|
$4.08M
|
-$1.53M
|
-58,417
|
-26%
|
|
