|
1
|
SV Health Investors
Boston,
Massachusetts
|
$52.4M
|
-$15.5M
|
-716,654
|
-28%
|
|
|
2
|
RA Capital Management
Boston,
Massachusetts
|
$41.2M
|
–
|
–
|
–
|
|
|
3
|
Vivo Capital
Palo Alto,
California
|
$38.9M
|
–
|
–
|
–
|
|
|
4
|
Polar Capital
London,
United Kingdom
|
$32.9M
|
+$23.2M
|
+1,070,300
|
+1,357%
|
|
|
5
|
VHCP Management III
New York
|
$27.8M
|
-$6.81M
|
-314,301
|
-24%
|
|
|
6
|
Eventide Asset Management
Boston,
Massachusetts
|
$25.8M
|
–
|
–
|
–
|
|
|
7
|
Fidelity Investments
Boston,
Massachusetts
|
$21M
|
+$15.9M
|
+735,014
|
New
|
|
|
8
|
Adage Capital Partners
Boston,
Massachusetts
|
$19M
|
+$1.41M
|
+65,000
|
+11%
|
|
|
9
|
Deerfield Management
New York
|
$18.6M
|
–
|
–
|
–
|
|
|
10
|
VHCP Management II
New York
|
$16.4M
|
-$4.03M
|
-185,699
|
-24%
|
|
|
11
|
Ghost Tree Capital
New York
|
$11.4M
|
-$542K
|
-25,000
|
-6%
|
|
|
12
|
InterWest Venture Management
San Francisco,
California
|
$11.1M
|
–
|
–
|
–
|
|
|
13
|
Vanguard Group
Malvern,
Pennsylvania
|
$10.2M
|
+$359K
|
+16,547
|
+5%
|
|
|
14
|
|
$8.98M
|
+$808K
|
+37,268
|
+13%
|
|
|
15
|
International Biotechnology Trust
London,
United Kingdom
|
$6.06M
|
-$2.31M
|
-106,383
|
-33%
|
|
|
16
|
Acuta Capital Partners
Redwood City,
California
|
$5.88M
|
+$705K
|
+32,500
|
+19%
|
|
|
17
|
Boxer Capital
San Diego,
California
|
$5.72M
|
–
|
–
|
–
|
|
|
18
|
Renaissance Technologies
New York
|
$4.58M
|
-$418K
|
-19,300
|
-11%
|
|
|
19
|
Samsara BioCapital
Palo Alto,
California
|
$3.39M
|
-$683K
|
-31,500
|
-21%
|
|
|
20
|
Millennium Management
New York
|
$2.76M
|
+$2.09M
|
+96,470
|
New
|
|
|
21
|
|
$2.59M
|
+$1.96M
|
+90,500
|
New
|
|
|
22
|
Geode Capital Management
Boston,
Massachusetts
|
$2.38M
|
-$17K
|
-786
|
-0.9%
|
|
|
23
|
Dimensional Fund Advisors
Austin,
Texas
|
$2.08M
|
+$1.33M
|
+61,414
|
+552%
|
|
|
24
|
Fosun International
Hong Kong,
China
|
$2.03M
|
-$1.41M
|
-64,837
|
-47%
|
|
|
25
|
|
$2.01M
|
+$546K
|
+25,179
|
+56%
|
|
