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KALA BIO

Name Holding Trade Value Shares
Change
Change in
Stake
RCM
1
RA Capital Management
Massachusetts
$13.2M
BlackRock
2
BlackRock
New York
$3.79M -$984K -212 -14%
Vanguard Group
3
Vanguard Group
Pennsylvania
$2.62M -$190K -41 -5%
State Street
4
State Street
Massachusetts
$1.35M +$9.28K +2 +0.4%
VAFP
5
Vahanian & Associates Financial Planning
New York
$1.27M +$1.94M +419 New
Geode Capital Management
6
Geode Capital Management
Massachusetts
$985K -$223K -48 -13%
PAMS
7
Pictet Asset Management (Switzerland)
Switzerland
$776K +$464K +100 +64%
SB
8
Samsara BioCapital
California
$727K
Bank of America
9
Bank of America
North Carolina
$618K +$872K +188 +1,175%
Northern Trust
10
Northern Trust
Illinois
$543K -$111K -24 -12%
BNP Paribas Financial Markets
11
BNP Paribas Financial Markets
France
$540K +$812K +175 +4,375%
KOCAA
12
Knights of Columbus Asset Advisors
Connecticut
$293K +$9.28K +2 +2%
Morgan Stanley
13
Morgan Stanley
New York
$260K -$172K -37 -30%
Goldman Sachs
14
Goldman Sachs
New York
$246K +$88.2K +19 +31%
Nuveen
15
Nuveen
North Carolina
$221K -$9.28K -2 -3%
T. Rowe Price Associates
16
T. Rowe Price Associates
Maryland
$211K +$74.2K +16 +30%
Bank of New York Mellon
17
Bank of New York Mellon
New York
$188K -$65K -14 -18%
PPA
18
Parametric Portfolio Associates
Washington
$180K +$51K +11 +23%
VF
19
Virtu Financial
New York
$153K +$237K +51 New
Renaissance Technologies
20
Renaissance Technologies
New York
$152K -$78.9K -17 -25%
Susquehanna International Group
21
Susquehanna International Group
Pennsylvania
$145K -$27.8K -6 -11%
Charles Schwab
22
Charles Schwab
California
$144K
Citadel Advisors
23
Citadel Advisors
Florida
$130K -$4.64K -1 -2%
D.E. Shaw & Co
24
D.E. Shaw & Co
New York
$130K +$199K +43 New
EAM
25
Erste Asset Management
Austria
$122K