|
1
|
RA Capital Management
Boston,
Massachusetts
|
$95.6M
|
+$40.5M
|
+2,537
|
+140%
|
|
|
2
|
|
$47.5M
|
+$12.5M
|
+782
|
+57%
|
|
|
3
|
Eventide Asset Management
Boston,
Massachusetts
|
$26M
|
+$18.9M
|
+1,182
|
New
|
|
|
4
|
Fidelity Investments
Boston,
Massachusetts
|
$25.1M
|
+$18.2M
|
+1,142
|
New
|
|
|
5
|
Vanguard Group
Malvern,
Pennsylvania
|
$17.5M
|
+$5.8M
|
+363
|
+83%
|
|
|
6
|
Caxton Corporation
Princeton,
New Jersey
|
$16.1M
|
+$2.25M
|
+141
|
+24%
|
|
|
7
|
|
$13.9M
|
+$1.01M
|
+63
|
+11%
|
|
|
8
|
Banco Bilbao Vizcaya Argentaria
Madrid,
Spain
|
$12.3M
|
–
|
–
|
–
|
|
|
9
|
Sofinnova Investments
Menlo Park,
California
|
$9.8M
|
+$2.88M
|
+180
|
+68%
|
|
|
10
|
Millennium Management
New York
|
$7.4M
|
+$1.87M
|
+117
|
+53%
|
|
|
11
|
Opaleye Management
Boston,
Massachusetts
|
$7.23M
|
+$5M
|
+313
|
New
|
|
|
12
|
Vivo Capital
Palo Alto,
California
|
$6.92M
|
+$5.03M
|
+315
|
New
|
|
|
13
|
Polaris Venture Management Co V
Boston,
Massachusetts
|
$4.97M
|
–
|
–
|
–
|
|
|
14
|
Driehaus Capital Management
Chicago,
Illinois
|
$4.43M
|
+$3.23M
|
+202
|
New
|
|
|
15
|
Ikarian Capital
Dallas,
Texas
|
$4.34M
|
-$3.39M
|
-212
|
-52%
|
|
|
16
|
Dimensional Fund Advisors
Austin,
Texas
|
$4.21M
|
–
|
–
|
–
|
|
|
17
|
|
$3.82M
|
+$2.35M
|
+147
|
+544%
|
|
|
18
|
State Street
Boston,
Massachusetts
|
$3.77M
|
+$431K
|
+27
|
+19%
|
|
|
19
|
Bank of America
Charlotte,
North Carolina
|
$3.42M
|
+$2.05M
|
+128
|
+457%
|
|
|
20
|
|
$3.28M
|
+$2.38M
|
+149
|
New
|
|
|
21
|
Geode Capital Management
Boston,
Massachusetts
|
$3.03M
|
+$47.9K
|
+3
|
+2%
|
|
|
22
|
Northern Trust
Chicago,
Illinois
|
$2.49M
|
+$320K
|
+20
|
+21%
|
|
|
23
|
Alyeska Investment Group
Chicago,
Illinois
|
$2.19M
|
-$1.2M
|
-75
|
-43%
|
|
|
24
|
Citadel Advisors
Miami,
Florida
|
$2.18M
|
+$735K
|
+46
|
+87%
|
|
|
25
|
Parkman Healthcare Partners
Stamford,
Connecticut
|
$1.98M
|
+$1.44M
|
+90
|
New
|
|
