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Ironwood Pharmaceuticals

155 hedge funds and large institutions have $105M invested in Ironwood Pharmaceuticals in 2025 Q2 according to their latest regulatory filings, with 19 funds opening new positions, 60 increasing their positions, 51 reducing their positions, and 64 closing their positions.

New
Increased
Maintained
Reduced
Closed

18% more repeat investments, than reductions

Existing positions increased: 60 | Existing positions reduced: 51

0% more funds holding in top 10

Funds holding in top 10: 11 (0)

6.8% less ownership

Funds ownership: 97.15%90.35% (-6.8%)

23% less funds holding

Funds holding: 200155 (-45)

54% less capital invested

Capital invested by funds: $229M → $105M (-$124M)

70% less first-time investments, than exits

New positions opened: 19 | Existing positions closed: 64

Holders
155
Holders Change
-45
Holders Change %
-22.5%
% of All Funds
2.04%
Holding in Top 10
1
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
0.01%
New
19
Increased
60
Reduced
51
Closed
64
Calls
$8.06M
Puts
Net Calls
+$8.06M
Net Calls Change
-$8.42M
Name Holding Trade Value Shares
Change
Change in
Stake
Vanguard Group
1
Vanguard Group
Pennsylvania
$11.6M +$397K +505,968 +3%
AC
2
Armistice Capital
New York
$11.6M +$1.92M +2,450,000 +18%
SCM
3
Sarissa Capital Management
Connecticut
$11.4M -$369K -470,565 -3%
BlackRock
4
BlackRock
New York
$8.62M +$113K +144,074 +1%
Renaissance Technologies
5
Renaissance Technologies
New York
$6.03M -$1.2M -1,534,323 -15%
Acadian Asset Management
6
Acadian Asset Management
Massachusetts
$4.68M +$3.07M +3,904,498 +148%
AQR Capital Management
7
AQR Capital Management
Connecticut
$4.42M +$2.86M +3,641,762 +144%
KCM
8
Kynam Capital Management
New Jersey
$3.92M -$280K -356,113 -6%
Marshall Wace
9
Marshall Wace
United Kingdom
$2.88M +$2.7M +3,436,036 +616%
Charles Schwab
10
Charles Schwab
California
$2.63M +$799K +1,017,261 +38%
Geode Capital Management
11
Geode Capital Management
Massachusetts
$2.51M +$63.8K +81,243 +2%
Two Sigma Advisers
12
Two Sigma Advisers
New York
$2.43M +$1.18M +1,499,500 +80%
Bank of America
13
Bank of America
North Carolina
$2.41M +$1.51M +1,929,356 +135%
Qube Research & Technologies (QRT)
14
Qube Research & Technologies (QRT)
United Kingdom
$2.4M +$34.5K +43,943 +1%
State Street
15
State Street
Massachusetts
$2.23M -$307K -390,570 -11%
Two Sigma Investments
16
Two Sigma Investments
New York
$1.97M +$1.2M +1,523,377 +124%
LSV Asset Management
17
LSV Asset Management
Illinois
$1.97M -$979K -1,247,601 -31%
Connor, Clark & Lunn Investment Management (CC&L)
18
Connor, Clark & Lunn Investment Management (CC&L)
British Columbia, Canada
$1.58M +$564K +718,904 +48%
Federated Hermes
19
Federated Hermes
Pennsylvania
$1.56M +$684K +871,676 +67%
Jane Street
20
Jane Street
New York
$1.25M -$1.39M -1,764,995 -50%
D.E. Shaw & Co
21
D.E. Shaw & Co
New York
$1.2M +$1.22M +1,559,915 +1,422%
Deutsche Bank
22
Deutsche Bank
Germany
$1.1M -$24.2K -30,817 -2%
Jacobs Levy Equity Management
23
Jacobs Levy Equity Management
New Jersey
$1.06M -$82.7K -105,274 -7%
Goldman Sachs
24
Goldman Sachs
New York
$1.04M -$103K -130,686 -8%
Northern Trust
25
Northern Trust
Illinois
$936K -$79.5K -101,269 -7%

IRWD Hedge Fund Activity: Q2 2025 in Review

155 of the 7,595 institutional investors tracked by Wall St. Rank reported a position in Ironwood Pharmaceuticals (IRWD) for Q2 2025, worth a combined $105M — down 54% from $229M a quarter earlier.

Sellers outnumbered buyers: 64 funds closed out of IRWD and 19 opened new positions — a net loss of 45 holders — while 51 trimmed existing stakes and 60 added.

The largest buyer was Acadian Asset Management, adding an estimated $3.07M. The largest seller was Braidwell, exiting entirely with an estimated $9.74M sold.

  • 155 institutional investors held Ironwood Pharmaceuticals (IRWD) as of Q2 2025, down from 200 in Q1 2025.
  • Funds reported $105M of Ironwood Pharmaceuticals stock for Q2 2025, down 54% quarter-over-quarter.
  • 19 funds opened new Ironwood Pharmaceuticals positions in Q2 2025 and 64 closed out, a net change of -45 holders.
  • The largest Ironwood Pharmaceuticals buyer in Q2 2025 was Acadian Asset Management, an estimated $3.07M added.
  • The largest Ironwood Pharmaceuticals seller in Q2 2025 was Braidwell, an estimated $9.74M sold.

Based on aggregated 13F filings for Q2 2025.