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Ironwood Pharmaceuticals

200 hedge funds and large institutions have $229M invested in Ironwood Pharmaceuticals in 2025 Q1 according to their latest regulatory filings, with 29 funds opening new positions, 74 increasing their positions, 63 reducing their positions, and 51 closing their positions.

New
Increased
Maintained
Reduced
Closed

164,720% more call options, than puts

Call options by funds: $16.5M | Put options by funds: $10K

17% more repeat investments, than reductions

Existing positions increased: 74 | Existing positions reduced: 63

0% more funds holding in top 10

Funds holding in top 10: 11 (0)

5.46% less ownership

Funds ownership: 102.61%97.15% (-5.5%)

10% less funds holding

Funds holding: 223200 (-23)

43% less first-time investments, than exits

New positions opened: 29 | Existing positions closed: 51

69% less capital invested

Capital invested by funds: $727M → $229M (-$499M)

Holders
200
Holders Change
-23
Holders Change %
-10.31%
% of All Funds
2.68%
Holding in Top 10
1
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
0.01%
New
29
Increased
74
Reduced
63
Closed
51
Calls
$16.5M
Puts
$10K
Net Calls
+$16.5M
Net Calls Change
-$34.2M
Name Holding Trade Value Shares
Change
Change in
Stake
SCM
1
Sarissa Capital Management
Connecticut
$24.1M
Vanguard Group
2
Vanguard Group
Pennsylvania
$23.1M -$9.15M -3,842,394 -20%
AC
3
Armistice Capital
New York
$20.1M +$10.1M +4,232,000 +45%
BlackRock
4
BlackRock
New York
$17.5M -$26.6M -11,158,411 -48%
Renaissance Technologies
5
Renaissance Technologies
New York
$14.6M +$2.08M +874,251 +10%
B
6
Braidwell
Connecticut
$9.74M +$2.82M +1,182,307 +22%
Millennium Management
7
Millennium Management
New York
$9.35M +$9.95M +4,179,239 +192%
KCM
8
Kynam Capital Management
New Jersey
$8.56M +$2.71M +1,137,375 +24%
LSV Asset Management
9
LSV Asset Management
Illinois
$5.88M -$199K -83,700 -2%
Jane Street
10
Jane Street
New York
$5.16M +$7.37M +3,092,475 +740%
State Street
11
State Street
Massachusetts
$5.14M -$11.5M -4,830,528 -58%
Geode Capital Management
12
Geode Capital Management
Massachusetts
$5.03M +$266K +111,519 +3%
Qube Research & Technologies (QRT)
13
Qube Research & Technologies (QRT)
United Kingdom
$4.86M +$7.26M +3,049,329 +1,183%
Charles Schwab
14
Charles Schwab
California
$3.89M +$1.58M +663,775 +33%
Acadian Asset Management
15
Acadian Asset Management
Massachusetts
$3.88M +$3.88M +1,630,726 +161%
AQR Capital Management
16
AQR Capital Management
Connecticut
$3.71M +$5.07M +2,126,889 +536%
Two Sigma Advisers
17
Two Sigma Advisers
New York
$2.77M +$1.55M +650,600 +53%
Morgan Stanley
18
Morgan Stanley
New York
$2.74M -$5.15M -2,161,472 -54%
Pacer Advisors
19
Pacer Advisors
Pennsylvania
$2.63M -$23.7M -9,941,673 -85%
JP Morgan Chase
20
JP Morgan Chase
New York
$2.5M +$1.5M +628,127 +58%
Jacobs Levy Equity Management
21
Jacobs Levy Equity Management
New Jersey
$2.32M -$4.87M -2,042,706 -56%
Goldman Sachs
22
Goldman Sachs
New York
$2.32M +$1.57M +660,144 +72%
Deutsche Bank
23
Deutsche Bank
Germany
$2.28M -$31.9K -13,381 -0.9%
Point72 Asset Management
24
Point72 Asset Management
Connecticut
$2.25M +$909K +381,557 +33%
Connor, Clark & Lunn Investment Management (CC&L)
25
Connor, Clark & Lunn Investment Management (CC&L)
British Columbia, Canada
$2.19M +$2.73M +1,146,589 +336%

IRWD Hedge Fund Activity: Q1 2025 in Review

200 of the 7,459 institutional investors tracked by Wall St. Rank reported a position in Ironwood Pharmaceuticals (IRWD) for Q1 2025, worth a combined $229M — down 69% from $727M a quarter earlier.

Sellers outnumbered buyers: 51 funds closed out of IRWD and 29 opened new positions — a net loss of 22 holders — while 63 trimmed existing stakes and 74 added.

The largest buyer was Armistice Capital, adding an estimated $10.1M. The largest seller was BlackRock, cutting an estimated $26.6M.

  • 200 institutional investors held Ironwood Pharmaceuticals (IRWD) as of Q1 2025, down from 223 in Q4 2024.
  • Funds reported $229M of Ironwood Pharmaceuticals stock for Q1 2025, down 69% quarter-over-quarter.
  • 29 funds opened new Ironwood Pharmaceuticals positions in Q1 2025 and 51 closed out, a net change of -22 holders.
  • The largest Ironwood Pharmaceuticals buyer in Q1 2025 was Armistice Capital, an estimated $10.1M added.
  • The largest Ironwood Pharmaceuticals seller in Q1 2025 was BlackRock, an estimated $26.6M sold.

Based on aggregated 13F filings for Q1 2025.