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Ironwood Pharmaceuticals
IRWD

166 hedge funds and large institutions have $195M invested in Ironwood Pharmaceuticals in 2025 Q3 according to their latest regulatory filings, with 30 funds opening new positions, 52 increasing their positions, 48 reducing their positions, and 18 closing their positions.

New
Increased
Maintained
Reduced
Closed

56,558% more call options, than puts

Call options by funds: $14.7M | Put options by funds: $26K

86% more capital invested

Capital invested by funds: $105M → $195M (+$90M)

67% more first-time investments, than exits

New positions opened: 30 | Existing positions closed: 18

7% more funds holding

Funds holding: 155 → 166 (+11)

1.17% more ownership

Funds ownership: 90.35% → 91.52% (+1.2%)

8% more repeat investments, than reductions

Existing positions increased: 52 | Existing positions reduced: 48

0% more funds holding in top 10

Funds holding in top 10: 1 → 1 (0)

Holders
166
Holders Change
+11
Holders Change %
+7.1%
% of All Funds
2.18%
Holding in Top 10
1
Holding in Top 10 Change
–
Holding in Top 10 Change %
–
% of All Funds
0.01%
New
30
Increased
52
Reduced
48
Closed
18
Calls
$14.7M
Puts
$26K
Net Calls
+$14.7M
Net Calls Change
+$6.65M

Top Buyers

Rank Fund Capital Flow
1
Bank of America
Bank of America
North Carolina
+$8.63M
2
Charles Schwab
Charles Schwab
California
+$1.3M
3
Jane Street
Jane Street
New York
+$596K
4
HCM
Highbridge Capital Management
New York
+$556K
5
UBS Group
UBS Group
Switzerland
+$529K

Top Sellers

Rank Fund Capital Flow
1
LSV Asset Management
LSV Asset Management
Illinois
-$1.97M
2
D.E. Shaw & Co
D.E. Shaw & Co
New York
-$1.34M
3
Marshall Wace
Marshall Wace
United Kingdom
-$879K
4
AQR Capital Management
AQR Capital Management
Connecticut
-$815K
5
Qube Research & Technologies (QRT)
Qube Research & Technologies (QRT)
United Kingdom
-$563K
Name Holding Trade Value Shares
Change 		Change in
Stake
SEI Investments
26
SEI Investments
Pennsylvania
$896K – – –
IC
27
IEQ Capital
California
$867K +$176K +169,816 +35%
Citadel Advisors
28
Citadel Advisors
Florida
$844K +$346K +334,774 +108%
Fidelity Investments
29
Fidelity Investments
Massachusetts
$734K +$64.9K +62,744 +13%
HCM
30
Highbridge Capital Management
New York
$704K +$556K +537,252 New
Bank of New York Mellon
31
Bank of New York Mellon
New York
$659K +$16.5K +15,896 +3%
Morgan Stanley
32
Morgan Stanley
New York
$625K -$17.5K -16,934 -3%
D.E. Shaw & Co
33
D.E. Shaw & Co
New York
$488K -$1.34M -1,297,369 -78%
Invesco
34
Invesco
Georgia
$480K +$45.9K +44,385 +14%
SOW
35
State of Wyoming
Wyoming
$475K +$162K +156,763 +76%
Robeco Institutional Asset Management
36
Robeco Institutional Asset Management
Netherlands
$449K -$28.3K -27,336 -7%
Cerity Partners
37
Cerity Partners
New York
$444K -$663 -641 -0.2%
Russell Investments Group
38
Russell Investments Group
United Kingdom
$429K +$122K +117,706 +56%
GCP
39
GSA Capital Partners
United Kingdom
$405K -$426K -411,331 -57%
RA
40
Royce & Associates
New York
$394K -$213K -205,441 -41%
Barclays
41
Barclays
United Kingdom
$389K -$70.5K -68,132 -19%
TI
42
Tidal Investments
Wisconsin
$385K -$16.4K -15,843 -5%
Millennium Management
43
Millennium Management
New York
$328K +$159K +153,787 +160%
Carson Wealth (CWM LLC)
44
Carson Wealth (CWM LLC)
Nebraska
$305K +$51.8K +50,016 +27%
RhumbLine Advisers
45
RhumbLine Advisers
Massachusetts
$292K +$7.88K +7,611 +4%
OAC
46
OMERS Administration Corp
Ontario, Canada
$282K – – –
AllianceBernstein
47
AllianceBernstein
Tennessee
$261K – – –
ETC
48
Exchange Traded Concepts
Oklahoma
$256K -$151K -145,802 -43%
Wealth Enhancement Advisory Services
49
Wealth Enhancement Advisory Services
Minnesota
$235K +$29.9K +28,928 +23%
KK
50
KLP Kapitalforvaltning
Norway
$228K – – –
1
2
3 4 5

IRWD Hedge Fund Activity: Q3 2025 in Review

166 of the 7,621 institutional investors tracked by Wall St. Rank reported a position in Ironwood Pharmaceuticals (IRWD) for Q3 2025, worth a combined $195M — up 86% from $105M a quarter earlier.

Buyers outnumbered sellers: 30 funds opened new IRWD positions and 18 closed out — a net gain of 12 holders — while 52 added to existing stakes and 48 trimmed.

The largest buyer was Bank of America, adding an estimated $8.63M. The largest seller was LSV Asset Management, exiting entirely with an estimated $1.97M sold.

  • 166 institutional investors held Ironwood Pharmaceuticals (IRWD) as of Q3 2025, up from 155 in Q2 2025.
  • Funds reported $195M of Ironwood Pharmaceuticals stock for Q3 2025, up 86% quarter-over-quarter.
  • 30 funds opened new Ironwood Pharmaceuticals positions in Q3 2025 and 18 closed out, a net change of +12 holders.
  • The largest Ironwood Pharmaceuticals buyer in Q3 2025 was Bank of America, an estimated $8.63M added.
  • The largest Ironwood Pharmaceuticals seller in Q3 2025 was LSV Asset Management, an estimated $1.97M sold.

Based on aggregated 13F filings for Q3 2025.