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Ironwood Pharmaceuticals

200 hedge funds and large institutions have $229M invested in Ironwood Pharmaceuticals in 2025 Q1 according to their latest regulatory filings, with 29 funds opening new positions, 74 increasing their positions, 63 reducing their positions, and 51 closing their positions.

New
Increased
Maintained
Reduced
Closed

164,720% more call options, than puts

Call options by funds: $16.5M | Put options by funds: $10K

17% more repeat investments, than reductions

Existing positions increased: 74 | Existing positions reduced: 63

0% more funds holding in top 10

Funds holding in top 10: 11 (0)

5.46% less ownership

Funds ownership: 102.61%97.15% (-5.5%)

10% less funds holding

Funds holding: 223200 (-23)

43% less first-time investments, than exits

New positions opened: 29 | Existing positions closed: 51

69% less capital invested

Capital invested by funds: $727M → $229M (-$499M)

Holders
200
Holders Change
-23
Holders Change %
-10.31%
% of All Funds
2.68%
Holding in Top 10
1
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
0.01%
New
29
Increased
74
Reduced
63
Closed
51
Calls
$16.5M
Puts
$10K
Net Calls
+$16.5M
Net Calls Change
-$34.2M
Name Holding Trade Value Shares
Change
Change in
Stake
Bank of America
26
Bank of America
North Carolina
$2.1M +$1.79M +750,371 +111%
Northern Trust
27
Northern Trust
Illinois
$2.07M -$521K -218,576 -13%
Federated Hermes
28
Federated Hermes
Pennsylvania
$1.92M +$2.23M +934,886 +252%
Two Sigma Investments
29
Two Sigma Investments
New York
$1.8M +$866K +363,768 +42%
JAM
30
Jupiter Asset Management
United Kingdom
$1.8M
SCM
31
Sio Capital Management
New York
$1.5M +$262K +109,833 +12%
Citadel Advisors
32
Citadel Advisors
Florida
$1.38M +$905K +380,084 +68%
VCM
33
Voleon Capital Management
California
$1.28M +$1.88M +787,901 +952%
Mariner
34
Mariner
Kansas
$1.1M +$1.53M +644,036 +608%
RA
35
Royce & Associates
New York
$1.08M
Los Angeles Capital Management
36
Los Angeles Capital Management
California
$1.01M +$848K +356,087 +107%
Susquehanna International Group
37
Susquehanna International Group
Pennsylvania
$953K +$1.09M +455,976 +237%
Marshall Wace
38
Marshall Wace
United Kingdom
$820K +$1.33M +557,521 New
XT
39
XTX Topco
Cayman Islands
$812K +$1.21M +506,732 +1,104%
GCP
40
GSA Capital Partners
United Kingdom
$771K +$1.22M +510,809 +3,684%
Bank of New York Mellon
41
Bank of New York Mellon
New York
$734K -$1.14M -478,522 -49%
ECM
42
ExodusPoint Capital Management
New York
$727K +$1.18M +494,620 New
Fidelity Investments
43
Fidelity Investments
Massachusetts
$705K +$420K +176,468 +58%
N
44
Nuveen
North Carolina
$693K +$157K +66,007 +16%
Walleye Capital
45
Walleye Capital
New York
$634K -$354K -148,687 -26%
Universal-Beteiligungs- und Servicegesellschaft
46
Universal-Beteiligungs- und Servicegesellschaft
Germany
$614K -$19.5K -8,185 -2%
Robeco Institutional Asset Management
47
Robeco Institutional Asset Management
Netherlands
$560K
BNP Paribas Financial Markets
48
BNP Paribas Financial Markets
France
$550K +$600K +251,759 +205%
CFM
49
Catalyst Funds Management
Australia
$513K +$806K +338,340 +3,222%
Man Group
50
Man Group
United Kingdom
$491K -$50.3K -21,106 -6%

IRWD Hedge Fund Activity: Q1 2025 in Review

200 of the 7,459 institutional investors tracked by Wall St. Rank reported a position in Ironwood Pharmaceuticals (IRWD) for Q1 2025, worth a combined $229M — down 69% from $727M a quarter earlier.

Sellers outnumbered buyers: 51 funds closed out of IRWD and 29 opened new positions — a net loss of 22 holders — while 63 trimmed existing stakes and 74 added.

The largest buyer was Armistice Capital, adding an estimated $10.1M. The largest seller was BlackRock, cutting an estimated $26.6M.

  • 200 institutional investors held Ironwood Pharmaceuticals (IRWD) as of Q1 2025, down from 223 in Q4 2024.
  • Funds reported $229M of Ironwood Pharmaceuticals stock for Q1 2025, down 69% quarter-over-quarter.
  • 29 funds opened new Ironwood Pharmaceuticals positions in Q1 2025 and 51 closed out, a net change of -22 holders.
  • The largest Ironwood Pharmaceuticals buyer in Q1 2025 was Armistice Capital, an estimated $10.1M added.
  • The largest Ironwood Pharmaceuticals seller in Q1 2025 was BlackRock, an estimated $26.6M sold.

Based on aggregated 13F filings for Q1 2025.