|
1
|
T. Rowe Price Investment Management
Baltimore,
Maryland
|
$77M
|
+$5.91M
|
+720,663
|
+10%
|
|
|
2
|
Fidelity Investments
Boston,
Massachusetts
|
$57.4M
|
+$18.7M
|
+2,275,348
|
+58%
|
|
|
3
|
|
$53.7M
|
+$885K
|
+107,993
|
+2%
|
|
|
4
|
Redmile Group
San Francisco,
California
|
$45.3M
|
-$4.01M
|
-488,962
|
-9%
|
|
|
5
|
Enavate Sciences
Menlo Park,
California
|
$44.3M
|
–
|
–
|
–
|
|
|
6
|
Point72 Asset Management
Stamford,
Connecticut
|
$43.6M
|
+$2.67M
|
+325,128
|
+7%
|
|
|
7
|
Vanguard Group
Malvern,
Pennsylvania
|
$42.1M
|
+$1.79M
|
+217,761
|
+5%
|
|
|
8
|
EcoR1 Capital
San Francisco,
California
|
$37.9M
|
–
|
–
|
–
|
|
|
9
|
Opaleye Management
Boston,
Massachusetts
|
$32.8M
|
-$167K
|
-20,419
|
-0.6%
|
|
|
10
|
Primecap Management
Pasadena,
California
|
$28.1M
|
-$3.23M
|
-393,490
|
-12%
|
|
|
11
|
T. Rowe Price Associates
Baltimore,
Maryland
|
$27.7M
|
-$718K
|
-87,527
|
-3%
|
|
|
12
|
State Street
Boston,
Massachusetts
|
$23.4M
|
-$980K
|
-119,527
|
-5%
|
|
|
13
|
Toronto Dominion Bank
Toronto, Ontario,
Ontario, Canada
|
$19.4M
|
+$17.1M
|
+2,085,700
|
New
|
|
|
14
|
Jefferies Financial Group
New York
|
$19.4M
|
-$1.66M
|
-202,340
|
-9%
|
|
|
15
|
Geode Capital Management
Boston,
Massachusetts
|
$17.3M
|
+$964K
|
+117,523
|
+7%
|
|
|
16
|
Woodline Partners
San Francisco,
California
|
$15.4M
|
+$7.66K
|
+934
|
+0.1%
|
|
|
17
|
Readystate Asset Management
Chicago,
Illinois
|
$12.6M
|
+$9.26M
|
+1,129,346
|
+504%
|
|
|
18
|
Marshall Wace
London,
United Kingdom
|
$12.1M
|
-$2.57M
|
-312,956
|
-19%
|
|
|
19
|
Janus Henderson Group
London,
|
$9.68M
|
-$8.59M
|
-1,048,081
|
-50%
|
|
|
20
|
Polar Capital Holdings
London,
United Kingdom
|
$9.3M
|
+$8.2M
|
+1,000,000
|
New
|
|
|
21
|
Sofinnova Investments
Menlo Park,
California
|
$7.24M
|
-$83.5K
|
-10,190
|
-1%
|
|
|
22
|
Northern Trust
Chicago,
Illinois
|
$6.43M
|
-$56.1K
|
-6,844
|
-1%
|
|
|
23
|
Charles Schwab
San Francisco,
California
|
$5.95M
|
+$212K
|
+25,862
|
+4%
|
|
|
24
|
TD Asset Management
Toronto,
Ontario, Canada
|
$5.63M
|
-$10.1K
|
-1,232
|
-0.2%
|
|
|
25
|
|
$5.36M
|
-$356K
|
-43,408
|
-7%
|
|
