|
1
|
T. Rowe Price Investment Management
Baltimore,
Maryland
|
$58.4M
|
-$3.17M
|
-262,059
|
-5%
|
|
|
2
|
Redmile Group
San Francisco,
California
|
$51.3M
|
-$744K
|
-61,528
|
-1%
|
|
|
3
|
|
$43.8M
|
+$1.73M
|
+143,206
|
+4%
|
|
|
4
|
Fidelity Investments
Boston,
Massachusetts
|
$41.6M
|
-$3.69M
|
-305,484
|
-7%
|
|
|
5
|
EcoR1 Capital
San Francisco,
California
|
$41.2M
|
–
|
–
|
–
|
|
|
6
|
Enavate Sciences
Menlo Park,
California
|
$36.9M
|
+$42M
|
+3,478,261
|
New
|
|
|
7
|
Janus Henderson Group
London,
|
$36.7M
|
-$389K
|
-32,182
|
-0.9%
|
|
|
8
|
Vanguard Group
Malvern,
Pennsylvania
|
$31.9M
|
-$1.55M
|
-128,130
|
-4%
|
|
|
9
|
T. Rowe Price Associates
Baltimore,
Maryland
|
$24.2M
|
+$2.98M
|
+246,447
|
+12%
|
|
|
10
|
State Street
Boston,
Massachusetts
|
$22.6M
|
-$733K
|
-60,631
|
-3%
|
|
|
11
|
Opaleye Management
Boston,
Massachusetts
|
$21.7M
|
+$9.7M
|
+802,500
|
+65%
|
|
|
12
|
Jefferies Financial Group
New York
|
$21.2M
|
+$1.5M
|
+124,108
|
+7%
|
|
|
13
|
Geode Capital Management
Boston,
Massachusetts
|
$13.1M
|
+$259K
|
+21,396
|
+2%
|
|
|
14
|
Marshall Wace
London,
United Kingdom
|
$12.9M
|
-$3.04M
|
-251,228
|
-17%
|
|
|
15
|
Woodline Partners
San Francisco,
California
|
$10.4M
|
+$683K
|
+56,533
|
+6%
|
|
|
16
|
Sofinnova Investments
Menlo Park,
California
|
$7.93M
|
+$847K
|
+70,058
|
+10%
|
|
|
17
|
Point72 Asset Management
Stamford,
Connecticut
|
$7.31M
|
+$2.64M
|
+218,143
|
+46%
|
|
|
18
|
|
$6.89M
|
+$7.54M
|
+624,045
|
+2,540%
|
|
|
19
|
Northern Trust
Chicago,
Illinois
|
$5.49M
|
+$521K
|
+43,146
|
+9%
|
|
|
20
|
Adage Capital Partners
Boston,
Massachusetts
|
$5.31M
|
+$3.38M
|
+280,000
|
+127%
|
|
|
21
|
Charles Schwab
San Francisco,
California
|
$4.86M
|
+$179K
|
+14,775
|
+3%
|
|
|
22
|
TD Asset Management
Toronto,
Ontario, Canada
|
$4.5M
|
+$347K
|
+28,684
|
+7%
|
|
|
23
|
|
$4.24M
|
+$1.33M
|
+109,789
|
+38%
|
|
|
24
|
Renaissance Technologies
New York
|
$3.36M
|
+$3.68M
|
+304,700
|
+2,696%
|
|
|
25
|
Granahan Investment Management
Waltham,
Massachusetts
|
$3.34M
|
+$3.8M
|
+314,239
|
New
|
|
